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Roland Eils (1965-)

Name	Roland Eils
Zeit	1965- (Lebensdaten)
Ort	Deutschland
Geschlecht	männlich
Akademischer Grad bzw. Titel	Prof. Dr.
Beziehung	Institut für Medizinische Biometrie und Medizinische Informatik (Heidelberg) (seit 2017) Universität Heidelberg. Institut für Pharmazie und Molekulare Biotechnologie (2006-2018) Bioinformatik (Thema) Genetik (Thema) Biomedizin (Thema) Big Data (Thema) Mathematik (Studienfach) Informatik (Studienfach) Linguistik (Studienfach)
Weitere Angaben	promoviert im Fach Humangenetik, molekulare Zellbiologie; Direktor der Abteilung Bioinformatik & Funktionelle Genomik des Instituts für Pharmazie und Molekulare Biotechnologie (IPMB); am 1. April 2018 tritt Professor Roland Eils die Professur auf Lebenszeit für Digitale Gesundheit am Berliner Institut für Gesundheitsforschung/Berlin Institute of Health (BIH) und der Charité – Universitätsmedizin Berlin an
Datensatztyp	Person
GND-Nummer	1020648287
Datensatz-ID	1020648287
Beteiligt an alle anzeigen The commitment of the human cell atlas to humanity Sainsc: A Computational Tool for Segmentation‐Free Analysis of In Situ Capture Data Die Medizininformatik-Initiative im Überblick – Aufbau einer Gesundheitsforschungsdateninfrastruktur in Deutschland Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort Immune–epithelial cell cross‐talk enhances antiviral responsiveness to SARS‐CoV ‐2 in children 90K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection Uncovering the mechanisms and information content of CpG-resolved DNA methylation programming during hematopoietic differentiation Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system Metabolomic profiles predict individual multidisease outcomes ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19 Complement activation induces excessive T cell cytotoxicity in severe COVID-19 Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers Temporal control of the integrated stress response by a stochastic molecular switch The genomic and transcriptional landscape of primary central nervous system lymphoma The DNA methylation landscape of multiple myeloma shows extensive inter- and intrapatient heterogeneity that fuels transcriptomic variability Putative second hit rare genetic variants in families with seemingly GBA-associated Parkinson’s disease A gene expression based method inferring cellular composition of pancreatic ductal adenocarcinoma and its application in stratification analysis Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin Cell segmentation-free inference of cell types from in situ transcriptomics data Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas Optimization of strategies for overcoming therapy resistance in pancreatic cancer chemotherapy by mathematical modelling The COVID-19 PHARMACOME: a method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype Gene set inference from single-cell sequencing data using a hybrid of matrix factorization and variational autoencoders Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 Prospective multicentric validation of a novel prediction model for paroxysmal atrial fibrillation Genomic footprints of activated telomere maintenance mechanisms in cancer SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells Analysis of mutational signatures with yet another package for signature analysis Framework for quality assessment of whole genome cancer sequences Genomic footprints of activated telomere maintenance mechanisms in cancer NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis Segmentation-free inference of cell types from in situ transcriptomics data ShinyButchR: interactive NMF-based decomposition workflow of genome-scale datasets The landscape of viral associations in human cancers Publisher Correction: Leveraging implicit knowledge in neural networks for functional dissection and engineering of proteins Impact of cancer mutational signatures on transcription factor motifs in the human genome Leveraging implicit knowledge in neural networks for functional dissection and engineering of proteins Mutational patterns and regulatory networks in epigenetic subgroups of meningioma Defective homologous recombination DNA repair as therapeutic target in advanced chordoma Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands An interaction-based modeling approach to predict response to cancer drugs Defective homologous recombination DNA repair as therapeutic target in advanced chordoma Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma Mutational patterns and regulatory networks in epigenetic subgroups of meningioma Pheno-seq: linking visual features and gene expression in 3D cell culture systems Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance Segregation and potential functional impact of a rare stop-gain PABPC4L variant in familial atypical parkinsonism Somatic mutations and promotor methylation of the ryanodine receptor 2 is a common event in the pathogenesis of head and neck cancer TGF[beta]-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC Web-based design and analysis tools for CRISPR base editing Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9 Familial Cancer Variant Prioritization Pipeline version 2 (FCVPPv2) applied to a papillary thyroid cancer family Author Correction: The landscape of genomic alterations across childhood cancers Genomic features of renal cell carcinoma with venous tumor thrombus

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Katalog der Deutschen Nationalbibliothek

Roland Eils (1965-)

The commitment of the human cell atlas to humanity

Sainsc: A Computational Tool for Segmentation‐Free Analysis of In Situ Capture Data

Die Medizininformatik-Initiative im Überblick – Aufbau einer Gesundheitsforschungsdateninfrastruktur in Deutschland

Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort

Immune–epithelial cell cross‐talk enhances antiviral responsiveness to SARS‐CoV ‐2 in children

90K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection

Uncovering the mechanisms and information content of CpG-resolved DNA methylation programming during hematopoietic differentiation

Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer

Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system

Metabolomic profiles predict individual multidisease outcomes

ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19

Complement activation induces excessive T cell cytotoxicity in severe COVID-19

Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers

Temporal control of the integrated stress response by a stochastic molecular switch

The genomic and transcriptional landscape of primary central nervous system lymphoma

The DNA methylation landscape of multiple myeloma shows extensive inter- and intrapatient heterogeneity that fuels transcriptomic variability

Putative second hit rare genetic variants in families with seemingly GBA-associated Parkinson’s disease

A gene expression based method inferring cellular composition of pancreatic ductal adenocarcinoma and its application in stratification analysis

Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin

Cell segmentation-free inference of cell types from in situ transcriptomics data

Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas

Optimization of strategies for overcoming therapy resistance in pancreatic cancer chemotherapy by mathematical modelling

The COVID-19 PHARMACOME: a method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype

Gene set inference from single-cell sequencing data using a hybrid of matrix factorization and variational autoencoders

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

Prospective multicentric validation of a novel prediction model for paroxysmal atrial fibrillation

Genomic footprints of activated telomere maintenance mechanisms in cancer

SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells

Analysis of mutational signatures with yet another package for signature analysis

Framework for quality assessment of whole genome cancer sequences

Genomic footprints of activated telomere maintenance mechanisms in cancer

NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis

Segmentation-free inference of cell types from in situ transcriptomics data

ShinyButchR: interactive NMF-based decomposition workflow of genome-scale datasets

The landscape of viral associations in human cancers

Publisher Correction: Leveraging implicit knowledge in neural networks for functional dissection and engineering of proteins

Impact of cancer mutational signatures on transcription factor motifs in the human genome

Leveraging implicit knowledge in neural networks for functional dissection and engineering of proteins

Mutational patterns and regulatory networks in epigenetic subgroups of meningioma

Defective homologous recombination DNA repair as therapeutic target in advanced chordoma

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma

Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands

An interaction-based modeling approach to predict response to cancer drugs

Defective homologous recombination DNA repair as therapeutic target in advanced chordoma

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma

Mutational patterns and regulatory networks in epigenetic subgroups of meningioma

Pheno-seq: linking visual features and gene expression in 3D cell culture systems

Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance

Segregation and potential functional impact of a rare stop-gain PABPC4L variant in familial atypical parkinsonism

Somatic mutations and promotor methylation of the ryanodine receptor 2 is a common event in the pathogenesis of head and neck cancer

TGF[beta]-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC

Web-based design and analysis tools for CRISPR base editing

Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer

Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9

Familial Cancer Variant Prioritization Pipeline version 2 (FCVPPv2) applied to a papillary thyroid cancer family

Author Correction: The landscape of genomic alterations across childhood cancers

Genomic features of renal cell carcinoma with venous tumor thrombus