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Person

Karsten Rippe

Name	Karsten Rippe
Ort	Deutschland
Geschlecht	männlich
Akademischer Grad bzw. Titel	Prof. Dr.
Beziehung	BioQuant (03/2016-12/2020)
Weitere Angaben	Since April 2007 group leader of the Research Group Genome Organization & Function at the DKFZ and the BioQuant; Group leader of the Molecular Biophysics Group (Junior Research Group of the Volkswagenstiftung) at the Kirchhoff-Institut für Physik at the University of Heidelberg
Datensatztyp	Person
GND-Nummer	102853261X
Datensatz-ID	102853261X
Beteiligt an alle anzeigen Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level Hepatitis D infection induces IFN-β-mediated NK cell activation and TRAIL-dependent cytotoxicity = Hepatitis D infection induces IFN-[Beta]-mediated NK cell activation and TRAIL-dependent cytotoxicity Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling Perturbing and imaging nuclear compartments to reveal mechanisms of transcription regulation and telomere maintenance Progenitor like cell type of an MLL-EDC4 fusion in acute myeloid leukemia Regulation of differential stress response and population composition during the growth of Bacillus subtilis The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer Comparison of single cell transcriptomics technologies and their application to investigate cellular heterogeneity in healthy and diseased lung Dissecting heterogeneity, clonal evolution, and epigenetic changes in distinct and molecularly defined AML subsets by multi omics single-cell sequencing Exploring therapeutic vulnerabilities in tumours with GLI1 oncogene activation Heterogeneity and multi-omics features of alternative lengthening of telomeres Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging Developmental programs in neuroblastoma dissected by single-cell analysis Disease- and drug-induced chromatin state changes in blood cancers Epigenetic signals that direct cell type specific interferon beta response in mouse cells On the significance of Toc-GTPase homodimers Regulation of transcription by transcription factor residence time and multivalent interactions Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL Genomic footprints of activated telomere maintenance mechanisms in cancer Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels Genomic footprints of activated telomere maintenance mechanisms in cancer Mixed Integer Linear Programming based approaches to study telomere maintenance mechanisms Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach Hyperparameter optimization for image analysis: application to prostate tissue images and live cell data of virus-infected cells TelomereHunter – in silico estimation of telomere content and composition from cancer genomes Deciphering Potential Role of Unfolded Protein Response in Glioblastoma Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks Pheno-seq: linking visual features and gene expression in 3D cell culture systems TelNet - a database for human and yeast genes involved in telomere maintenance Integrative genomic and transcriptomic analysis of leiomyosarcoma Inducing and suppressing the alternative lengthening of telomeres mechanism in cancer cells Investigating the role of DNA damage repair processes in catastrophic genomic events Silencing and activating heterochromatin NucTools: analysis of chromatin feature occupancy profiles from high-throughput sequencing data A 3’-UTR sequence element modifies chromatin and regulates alternative splicing CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality Dynamic properties of independent chromatin domains measured by correlation spectroscopy in living cells Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children Towards a mechanistic understanding of telomere loop structures in S. cerevisiae Alu element‐containing RNA s maintain nucleolar structure and function Identification and characterization of genes deregulated by DNA methylation in chronic lymphocytic leukemia Characterizing mitochondrial function and structure – Mitochondrial regulation of apoptosis and visualization of mitochondria - endoplasmic reticulum interactions Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the in cis downregulation of a gene cluster that targets NF-kB Hypermutation of the inactive X chromosome is a frequent event in cancer Genome organization and function in the cell nucleus Genome Organization And Function In The Cell Nucleus Genome Organization And Function In The Cell Nucleus Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development Dissecting chromatin interactions in living cells from protein mobility maps Versuche zur Strukturaufklärung und physiologischen Bedeutung von parallelsträngiger DNA

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Karsten Rippe

Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage

Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level

Hepatitis D infection induces IFN-β-mediated NK cell activation and TRAIL-dependent cytotoxicity = Hepatitis D infection induces IFN-[Beta]-mediated NK cell activation and TRAIL-dependent cytotoxicity

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

Perturbing and imaging nuclear compartments to reveal mechanisms of transcription regulation and telomere maintenance

Progenitor like cell type of an MLL-EDC4 fusion in acute myeloid leukemia

Regulation of differential stress response and population composition during the growth of Bacillus subtilis

The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients

Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer

Comparison of single cell transcriptomics technologies and their application to investigate cellular heterogeneity in healthy and diseased lung

Dissecting heterogeneity, clonal evolution, and epigenetic changes in distinct and molecularly defined AML subsets by multi omics single-cell sequencing

Exploring therapeutic vulnerabilities in tumours with GLI1 oncogene activation

Heterogeneity and multi-omics features of alternative lengthening of telomeres

Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging

Developmental programs in neuroblastoma dissected by single-cell analysis

Disease- and drug-induced chromatin state changes in blood cancers

Epigenetic signals that direct cell type specific interferon beta response in mouse cells

On the significance of Toc-GTPase homodimers

Regulation of transcription by transcription factor residence time and multivalent interactions

Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL

Genomic footprints of activated telomere maintenance mechanisms in cancer

Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels

Genomic footprints of activated telomere maintenance mechanisms in cancer

Mixed Integer Linear Programming based approaches to study telomere maintenance mechanisms

Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach

Hyperparameter optimization for image analysis: application to prostate tissue images and live cell data of virus-infected cells

TelomereHunter – in silico estimation of telomere content and composition from cancer genomes

Deciphering Potential Role of Unfolded Protein Response in Glioblastoma

Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks

Pheno-seq: linking visual features and gene expression in 3D cell culture systems

TelNet - a database for human and yeast genes involved in telomere maintenance

Integrative genomic and transcriptomic analysis of leiomyosarcoma

Inducing and suppressing the alternative lengthening of telomeres mechanism in cancer cells

Investigating the role of DNA damage repair processes in catastrophic genomic events

Silencing and activating heterochromatin

NucTools: analysis of chromatin feature occupancy profiles from high-throughput sequencing data

A 3’-UTR sequence element modifies chromatin and regulates alternative splicing

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality

Dynamic properties of independent chromatin domains measured by correlation spectroscopy in living cells

Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children

Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children

Towards a mechanistic understanding of telomere loop structures in S. cerevisiae

Alu element‐containing RNA s maintain nucleolar structure and function

Identification and characterization of genes deregulated by DNA methylation in chronic lymphocytic leukemia

Characterizing mitochondrial function and structure – Mitochondrial regulation of apoptosis and visualization of mitochondria - endoplasmic reticulum interactions

Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the in cis downregulation of a gene cluster that targets NF-kB

Hypermutation of the inactive X chromosome is a frequent event in cancer

Genome organization and function in the cell nucleus

Genome Organization And Function In The Cell Nucleus

Genome Organization And Function In The Cell Nucleus

Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development

Dissecting chromatin interactions in living cells from protein mobility maps

Versuche zur Strukturaufklärung und physiologischen Bedeutung von parallelsträngiger DNA