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Bettina Warscheid (1971-)

Chemikerin

Name	Bettina Warscheid
Zeit	1971- (Lebensdaten)
Ort	Deutschland
Geschlecht	weiblich
Beruf	Chemikerin (charakteristischer Beruf)
Beziehung	Albert-Ludwigs-Universität Freiburg. Centre for Biological Signalling Studies (2010-) Ruhr-Universität Bochum. Medizinisches Proteom-Center (-2010)
Weitere Angaben	1997-2002, Ph.D. student at the Institute for Analytical Sciences, Dortmund; 2002-2003, Postdoctoral fellow at the University of Maryland, College Park, MD, USA; 2003-2010, Group leader at the Medizinisches Proteom-Center, Ruhr-University of Bochum; 2004-2009, Junior-Professor for Protein Mass Spectrometry at the Medical Faculty, Ruhr- University of Bochum; 2009-2010, Professor for Clinical & Cellular Proteomics at the Medical Faculty and Centre for Medical Biotechnology, University of Duisburg-Essen; 2010-, Professor for Functional Proteomics, Centre for Biological Signalling Studies (bioss), Institute of Biology II, University of Freiburg
Datensatztyp	Person
GND-Nummer	1031390898
Datensatz-ID	1031390898
Beteiligt an alle anzeigen Identification of phosphatases that dephosphorylate the co-chaperone BAG3 Protein phosphatase-1 regulates the binding of filamin C to FILIP1 in cultured skeletal muscle cells under mechanical stress Ageing-dependent thiol oxidation reveals early oxidation of proteins with core proteostasis functions Identification of TFG- and autophagy-regulated proteins and glycerophospholipids in b cells Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria Protein phosphatase-1 regulates the binding of filamin C to FILIP1 in cultured skeletal muscle cells under mechanical stress Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context COX17 acetylation via MOF–KANSL complex promotes mitochondrial integrity and function Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes A Msp1-containing complex removes orphaned proteins in the mitochondrial outer membrane of T. brucei Analysis of Yeast Peroxisomes via Spatial Proteomics Conformational regulation and target-myristoyl switch of calcineurin B homologous protein 3 COX17 acetylation via MOF–KANSL complex promotes mitochondrial integrity and function Immunoproteasome-specific subunit PSMB9 induction is required to regulate cellular proteostasis upon mitochondrial dysfunction Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans The Mba1 homologue of Trypanosoma brucei is involved in the biogenesis of oxidative phosphorylation complexes A newly identified secreted larval antigen elicits basophil-dependent protective immunity against N. brasiliensis infection A newly identified secreted larval antigen elicits basophil-dependent protective immunity against N. brasiliensis infection Characterization of a highly diverged mitochondrial ATP synthase Fo subunit in Trypanosoma brucei Mistargeting of aggregation prone mitochondrial proteins activates a nucleus-mediated posttranscriptional quality control pathway in trypanosomes p166 links membrane and intramitochondrial modules of the trypanosomal tripartite attachment complex Regulating peroxisome–ER contacts via the ACBD5-VAPB tether by FFAT motif phosphorylation and GSK3β The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei Maintaining proteostasis under mechanical stress Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors Determinism and contingencies shaped the evolution of mitochondrial protein import DIMA: data-driven selection of an imputation algorithm DNA repair protein APE1 degrades dysfunctional abasic mRNA in mitochondria affecting oxidative phosphorylation Maintaining proteostasis under mechanical stress Molecular basis of F-actin regulation and sarcomere assembly via myotilin Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with α-actinin Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling Quantitative proteomics identifies the universally conserved ATPase Ola1p as a positive regulator of heat shock response in Saccharomyces cerevisiae The universally conserved ATPase YchF regulates translation of leaderless mRNA in response to stress conditions COA6 Facilitates cytochrome c oxidase biogenesis as thiol-reductase for copper metallochaperones in mitochondria Defining the substrate spectrum of the TIM22 complex identifies pyruvate carrier subunits as unconventional cargos Homologue replacement in the import motor of the mitochondrial inner membrane of trypanosomes Pex14p phosphorylation modulates import of citrate synthase 2 into peroxisomes in saccharomyces cerevisiae Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C Mitochondrial proteins: from biogenesis to functional networks Light-controlled affinity purification of protein complexes exemplified by the resting ZAP70 interactome Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species Recruitment of cytosolic J-proteins by TOM receptors promotes mitochondrial protein biogenesis The interaction network of the YidC insertase with the SecYEG translocon, SRP and the SRP receptor FtsY A trypanosomal orthologue of an intermembrane space chaperone has a non-canonical function in biogenesis of the single mitochondrial inner membrane protein translocase Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei Charting organellar importomes by quantitative mass spectrometry Definition of a high-confidence mitochondrial proteome at quantitative Scale Identification of new channels by systematic analysis of the mitochondrial outer membrane INA complex liaises the F1Fo-ATP synthase membrane motor modules Membrane localization of acetylated CNK1 mediates a positive feedback on RAF/ERK signaling Myofibrillar Z-discs are a protein phosphorylation hot spot with protein kinase C (PKCα) modulating protein dynamics = Myofibrillar Z-discs are a protein phosphorylation hot spot with protein kinase C (PKC[alpha]) modulating protein dynamics PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy Structural features of the TatC membrane protein that determine docking and insertion of a twin-arginine signal peptide Identification of cell cycle dependent interaction partners of the septins by quantitative mass spectrometry Mitochondrial OXA translocase plays a major role in biogenesis of inner-membrane proteins Mitochondrial protein synthesis adapts to influx of nuclear-encoded protein

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Bettina Warscheid (1971-)

Identification of phosphatases that dephosphorylate the co-chaperone BAG3

Protein phosphatase-1 regulates the binding of filamin C to FILIP1 in cultured skeletal muscle cells under mechanical stress

Ageing-dependent thiol oxidation reveals early oxidation of proteins with core proteostasis functions

Identification of TFG- and autophagy-regulated proteins and glycerophospholipids in b cells

Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria

Protein phosphatase-1 regulates the binding of filamin C to FILIP1 in cultured skeletal muscle cells under mechanical stress

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context

COX17 acetylation via MOF–KANSL complex promotes mitochondrial integrity and function

Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes

A Msp1-containing complex removes orphaned proteins in the mitochondrial outer membrane of T. brucei

Analysis of Yeast Peroxisomes via Spatial Proteomics

Conformational regulation and target-myristoyl switch of calcineurin B homologous protein 3

COX17 acetylation via MOF–KANSL complex promotes mitochondrial integrity and function

Immunoproteasome-specific subunit PSMB9 induction is required to regulate cellular proteostasis upon mitochondrial dysfunction

Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes

Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans

The Mba1 homologue of Trypanosoma brucei is involved in the biogenesis of oxidative phosphorylation complexes

A newly identified secreted larval antigen elicits basophil-dependent protective immunity against N. brasiliensis infection

A newly identified secreted larval antigen elicits basophil-dependent protective immunity against N. brasiliensis infection

Characterization of a highly diverged mitochondrial ATP synthase Fo subunit in Trypanosoma brucei

Mistargeting of aggregation prone mitochondrial proteins activates a nucleus-mediated posttranscriptional quality control pathway in trypanosomes

p166 links membrane and intramitochondrial modules of the trypanosomal tripartite attachment complex

Regulating peroxisome–ER contacts via the ACBD5-VAPB tether by FFAT motif phosphorylation and GSK3β

The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei

Maintaining proteostasis under mechanical stress

Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors

Determinism and contingencies shaped the evolution of mitochondrial protein import

DIMA: data-driven selection of an imputation algorithm

DNA repair protein APE1 degrades dysfunctional abasic mRNA in mitochondria affecting oxidative phosphorylation

Maintaining proteostasis under mechanical stress

Molecular basis of F-actin regulation and sarcomere assembly via myotilin

Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with α-actinin

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context

Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling

Quantitative proteomics identifies the universally conserved ATPase Ola1p as a positive regulator of heat shock response in Saccharomyces cerevisiae

The universally conserved ATPase YchF regulates translation of leaderless mRNA in response to stress conditions

COA6 Facilitates cytochrome c oxidase biogenesis as thiol-reductase for copper metallochaperones in mitochondria

Defining the substrate spectrum of the TIM22 complex identifies pyruvate carrier subunits as unconventional cargos

Homologue replacement in the import motor of the mitochondrial inner membrane of trypanosomes

Pex14p phosphorylation modulates import of citrate synthase 2 into peroxisomes in saccharomyces cerevisiae

Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C

Mitochondrial proteins: from biogenesis to functional networks

Light-controlled affinity purification of protein complexes exemplified by the resting ZAP70 interactome

Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species

Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species

Recruitment of cytosolic J-proteins by TOM receptors promotes mitochondrial protein biogenesis

The interaction network of the YidC insertase with the SecYEG translocon, SRP and the SRP receptor FtsY

A trypanosomal orthologue of an intermembrane space chaperone has a non-canonical function in biogenesis of the single mitochondrial inner membrane protein translocase

Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei

Charting organellar importomes by quantitative mass spectrometry

Definition of a high-confidence mitochondrial proteome at quantitative Scale

Identification of new channels by systematic analysis of the mitochondrial outer membrane

INA complex liaises the F1Fo-ATP synthase membrane motor modules

Membrane localization of acetylated CNK1 mediates a positive feedback on RAF/ERK signaling

Myofibrillar Z-discs are a protein phosphorylation hot spot with protein kinase C (PKCα) modulating protein dynamics = Myofibrillar Z-discs are a protein phosphorylation hot spot with protein kinase C (PKC[alpha]) modulating protein dynamics

PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy

Structural features of the TatC membrane protein that determine docking and insertion of a twin-arginine signal peptide

Identification of cell cycle dependent interaction partners of the septins by quantitative mass spectrometry

Mitochondrial OXA translocase plays a major role in biogenesis of inner-membrane proteins

Mitochondrial protein synthesis adapts to influx of nuclear-encoded protein