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Meinhard Kieser (1960-)

Mathematiker

Name	Meinhard Kieser
Zeit	1960- (Lebensdaten)
Ort	Heidelberg (Wirkungsort) Buchen (Odenwald) (Geburtsort) Deutschland
Geschlecht	männlich
Akademischer Grad bzw. Titel	Prof. Dr. sc. hum. (an der Medizinischen Fakultät Heidelberg der Ruprecht-Karls-Universität) (1992 und 2001) Dipl.-Math. (an der Ruprecht-Karls-Universität) (1986)
Beruf	Mathematiker (charakteristischer Beruf)
Variante	M. Kieser
Beziehung	Universität Heidelberg (Medizinische Biometrie) (01/2008-) Klinikum Heidelberg Universität Heidelberg. Medizinische Fakultät (Lehrbeauftragter) Biomathematik (Thema)
Weitere Angaben	seit 2007 Direktor des Instituts für Medizinische Biometrie, Universität Heidelberg
Quelle	https://www.klinikum.uni-heidelberg.de/personen/prof-dr-meinhard-kieser-3451 (Stand: 16.09.2024)
Datensatztyp	Person
GND-Nummer	103276547X
Datensatz-ID	103276547X
Beteiligt an alle anzeigen Use of class IC antiarrhythmic drugs in patients with structural heart disease and implantable cardioverter defibrillator Extension of a conditional performance score for sample size recalculation rules to the setting of binary endpoints Estimation, Testing and Sample Size Calculation Within the Responder Stratified Exponential Survival Model Impact of Institutional Research Activity on Quality of Care and Patient Outcome in Ovarian Cancer Point estimation, confidence intervals, and P‐values for optimal adaptive two‐stage designs with normal endpoints Q-HAM: a multicenter upfront randomized phase II trial of quizartinib and high-dose Ara-C plus mitoxantrone in relapsed/refractory AML with FLT3-ITD Using real‐world data to predict health outcomes—The prediction design: Application and sample size planning FASTER and SCOTT&EVA trainings for adults with high-functioning autism spectrum disorder (ASD): study protocol for a randomized controlled trial Network meta-analysis for the integrated evaluation of targeted therapies Improvement of functional outcome for patients with newly diagnosed grade 2 or 3 gliomas with co-deletion of 1p/19q – IMPROVE CODEL: the NOA-18 trial Neoadjuvant irradiation of extremity soft tissue sarcoma with ions (Extrem-ion): study protocol for a randomized phase II pilot trial Monotonicity conditions for avoiding counterintuitive decisions in basket trials Using independent cross‐sectional survey data to predict post‐migration health trajectories among refugees by estimating transition probabilities and their variances Systematic approach and investigation of the statistical tools in basket trial designs Glioblastoma radiotherapy using Intensity modulated Radiotherapy (IMRT) or proton Radiotherapy—GRIPS Trial (Glioblastoma Radiotherapy via IMRT or Proton BeamS): a study protocol for a multicenter, prospective, open-label, randomized, two-arm, phase III study Adenoid cystic Carcinoma and Carbon ion Only irradiation (ACCO): Study protocol for a prospective, open, randomized, two-armed, phase II study Hemodynamic Status During Endovascular Stroke Treatment: Association of Blood Pressure with Functional Outcome Categories, components, and techniques in a modular construction of basket trials for application and further research FASTER and SCOTT&EVA trainings for adults with high-functioning autism spectrum disorder (ASD): study protocol for a randomized controlled trial Prophylactic anticoagulation in patients with glioblastoma or brain metastases and atrial fibrillation: an increased risk for intracranial hemorrhage? Neoadjuvant irradiation of retroperitoneal soft tissue sarcoma with ions (Retro-Ion): study protocol for a randomized phase II pilot trial Applying Matching Procedures in the Generation and Synthesis of Evidence Children of mentally III parents at risk evaluation (COMPARE): design and methods of a randomized controlled multicenter study - part I Interventions to reduce the incidence of surgical site infection in colorectal resections: systematic review with multicomponent network meta-analysis (INTRISSI): study protocol Network meta-analysis in sparse networks of binary data Optimal adaptive two-stage designs for clinical trials with continuous test statistics Prophylactic anticoagulation in patients with glioblastoma or brain metastases and atrial fibrillation: an increased risk for intracranial hemorrhage? Rationale and design of the 2 by 2 factorial design GnG-trial: a randomized phase-III study to compare two schedules of gemtuzumab ozogamicin as adjunct to intensive induction therapy and to compare double-blinded intensive postremission therapy with or without glasdegib in older patients with newly diagnosed AML Optimal designs for phase II/III drug development programs including methods for discounting of phase II results Carbon ion radiotherapy as definitive treatment in non-metastasized pancreatic cancer: study protocol of the prospective phase II PACK-study Durvalumab in frail and elderly patients with stage four non-small cell lung cancer: Study protocol of the randomized phase II DURATION trial Study protocol of the multi-centre, randomised controlled trial of the Frankfurt Early Intervention Programme A-FFIP versus early intervention as usual for toddlers and preschool children with Autism Spectrum Disorder (A-FFIP study) Why do you need a biostatistician? Integrated evaluation of targeted and non‐targeted therapies in a network meta‐analysis Adjustment for exploratory cut‐off selection in randomized clinical trials with survival endpoint Choice of the Interim Analysis Timing in Adaptive Enrichment Designs Comparison of Methods for Estimating Therapy Effects by Indirect Comparisons: A Simulation Study Integrated planning of pilot and subsequent confirmatory study in clinical research : finding optimal designs in a utility-based framework Study protocol of the multi-centre, randomised controlled trial of the Frankfurt Early Intervention Programme A-FFIP versus early intervention as usual for toddlers and preschool children with Autism Spectrum Disorder (A-FFIP study) Psychometric validation of the Breast Cancer Treatment Outcome Scale (BCTOS-12): a prospective cohort study Fostering efficacy of anti-PD-1-treatment: Nivolumab plus radiotherapy in advanced non-small cell lung cancer - study protocol of the FORCE trial Adjuvant intensity modulated whole-abdominal radiation therapy for high-risk patients with ovarian cancer FIGO stage III: final results of a prospective phase 2 study Therapy of nodal Follicular Lymphoma (WHO grade 1/2) in clinical stage I/II using response adapted Involved Site Radiotherapy in combination with Obinutuzumab (Gazyvaro) - GAZAI Trial (GAZyvaro and response adapted Involved-site Radiotherapy): a study protocol for a single-arm, non-randomized, open, national, multi-center phase II trial Adaptive propensity score procedure improves matching in prospective observational trials Clinical effect of stannous fluoride and amine fluoride containing oral hygiene products: A 4-year randomized controlled pilot study COMPARE Family (Children of Mentally Ill Parents at Risk Evaluation): A Study Protocol for a Preventive Intervention for Children of Mentally Ill Parents (Triple P, Evidence-Based Program That Enhances Parentings Skills, in Addition to Gold-Standard CBT With the Mentally Ill Parent) in a Multicenter RCT—Part II Refining scores based on patient reported outcomes – statistical and medical perspectives Endovascular stroke treatment’s impact on malignant type of edema (ESTIMATE) Clinical management and prevention of dental caries in athletes: A four-year randomized controlled clinical trial Hypothesis testing in Bayesian network meta-analysis Whole brain radiation therapy alone versus radiosurgery for patients with 1–10 brain metastases from small cell lung cancer (ENCEPHALON Trial): study protocol for a randomized controlled trial Conduct disorder in adolescent females: current state of research and study design of the FemNAT-CD consortium Use of the wearable cardioverter-defibrillator (WCD) and WCD-based remote rhythm monitoring in a real-life patient cohort Time-to-first-event versus recurrent-event analysis: points to consider for selecting a meaningful analysis strategy in clinical trials with composite endpoints A comparison of group sequential and fixed sample size designs for bioequivalence trials with highly variable drugs A systematic comparison of recurrent event models for application to composite endpoints The Average Hazard Ratio – A Good Effect Measure for Time-to-event Endpoints when the Proportional Hazard Assumption is Violated? Fallzahlberechnung in der medizinischen Forschung : eine Einführung für Mediziner und Biostatistiker Fallzahlberechnung in der medizinischen Forschung : Eine Einführung für Mediziner und Biostatistiker Resting autonomic nervous system activity is unrelated to antisocial behaviour dimensions in adolescents : Cross-sectional findings from a European multi-centre study

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Katalog der Deutschen Nationalbibliothek

Meinhard Kieser (1960-)

Use of class IC antiarrhythmic drugs in patients with structural heart disease and implantable cardioverter defibrillator

Extension of a conditional performance score for sample size recalculation rules to the setting of binary endpoints

Estimation, Testing and Sample Size Calculation Within the Responder Stratified Exponential Survival Model

Impact of Institutional Research Activity on Quality of Care and Patient Outcome in Ovarian Cancer

Point estimation, confidence intervals, and P‐values for optimal adaptive two‐stage designs with normal endpoints

Q-HAM: a multicenter upfront randomized phase II trial of quizartinib and high-dose Ara-C plus mitoxantrone in relapsed/refractory AML with FLT3-ITD

Using real‐world data to predict health outcomes—The prediction design: Application and sample size planning

FASTER and SCOTT&EVA trainings for adults with high-functioning autism spectrum disorder (ASD): study protocol for a randomized controlled trial

Network meta-analysis for the integrated evaluation of targeted therapies

Improvement of functional outcome for patients with newly diagnosed grade 2 or 3 gliomas with co-deletion of 1p/19q – IMPROVE CODEL: the NOA-18 trial

Neoadjuvant irradiation of extremity soft tissue sarcoma with ions (Extrem-ion): study protocol for a randomized phase II pilot trial

Monotonicity conditions for avoiding counterintuitive decisions in basket trials

Using independent cross‐sectional survey data to predict post‐migration health trajectories among refugees by estimating transition probabilities and their variances

Systematic approach and investigation of the statistical tools in basket trial designs

Glioblastoma radiotherapy using Intensity modulated Radiotherapy (IMRT) or proton Radiotherapy—GRIPS Trial (Glioblastoma Radiotherapy via IMRT or Proton BeamS): a study protocol for a multicenter, prospective, open-label, randomized, two-arm, phase III study

Adenoid cystic Carcinoma and Carbon ion Only irradiation (ACCO): Study protocol for a prospective, open, randomized, two-armed, phase II study

Hemodynamic Status During Endovascular Stroke Treatment: Association of Blood Pressure with Functional Outcome

Categories, components, and techniques in a modular construction of basket trials for application and further research

FASTER and SCOTT&EVA trainings for adults with high-functioning autism spectrum disorder (ASD): study protocol for a randomized controlled trial

Prophylactic anticoagulation in patients with glioblastoma or brain metastases and atrial fibrillation: an increased risk for intracranial hemorrhage?

Neoadjuvant irradiation of retroperitoneal soft tissue sarcoma with ions (Retro-Ion): study protocol for a randomized phase II pilot trial

Applying Matching Procedures in the Generation and Synthesis of Evidence

Children of mentally III parents at risk evaluation (COMPARE): design and methods of a randomized controlled multicenter study - part I

Interventions to reduce the incidence of surgical site infection in colorectal resections: systematic review with multicomponent network meta-analysis (INTRISSI): study protocol

Network meta-analysis in sparse networks of binary data

Optimal adaptive two-stage designs for clinical trials with continuous test statistics

Prophylactic anticoagulation in patients with glioblastoma or brain metastases and atrial fibrillation: an increased risk for intracranial hemorrhage?

Optimal designs for phase II/III drug development programs including methods for discounting of phase II results

Carbon ion radiotherapy as definitive treatment in non-metastasized pancreatic cancer: study protocol of the prospective phase II PACK-study

Durvalumab in frail and elderly patients with stage four non-small cell lung cancer: Study protocol of the randomized phase II DURATION trial

Study protocol of the multi-centre, randomised controlled trial of the Frankfurt Early Intervention Programme A-FFIP versus early intervention as usual for toddlers and preschool children with Autism Spectrum Disorder (A-FFIP study)

Why do you need a biostatistician?

Integrated evaluation of targeted and non‐targeted therapies in a network meta‐analysis

Adjustment for exploratory cut‐off selection in randomized clinical trials with survival endpoint

Choice of the Interim Analysis Timing in Adaptive Enrichment Designs

Comparison of Methods for Estimating Therapy Effects by Indirect Comparisons: A Simulation Study

Integrated planning of pilot and subsequent confirmatory study in clinical research : finding optimal designs in a utility-based framework

Study protocol of the multi-centre, randomised controlled trial of the Frankfurt Early Intervention Programme A-FFIP versus early intervention as usual for toddlers and preschool children with Autism Spectrum Disorder (A-FFIP study)

Psychometric validation of the Breast Cancer Treatment Outcome Scale (BCTOS-12): a prospective cohort study

Fostering efficacy of anti-PD-1-treatment: Nivolumab plus radiotherapy in advanced non-small cell lung cancer - study protocol of the FORCE trial

Adjuvant intensity modulated whole-abdominal radiation therapy for high-risk patients with ovarian cancer FIGO stage III: final results of a prospective phase 2 study

Adaptive propensity score procedure improves matching in prospective observational trials

Clinical effect of stannous fluoride and amine fluoride containing oral hygiene products: A 4-year randomized controlled pilot study

Refining scores based on patient reported outcomes – statistical and medical perspectives

Endovascular stroke treatment’s impact on malignant type of edema (ESTIMATE)

Clinical management and prevention of dental caries in athletes: A four-year randomized controlled clinical trial

Hypothesis testing in Bayesian network meta-analysis

Whole brain radiation therapy alone versus radiosurgery for patients with 1–10 brain metastases from small cell lung cancer (ENCEPHALON Trial): study protocol for a randomized controlled trial

Conduct disorder in adolescent females: current state of research and study design of the FemNAT-CD consortium

Use of the wearable cardioverter-defibrillator (WCD) and WCD-based remote rhythm monitoring in a real-life patient cohort

Time-to-first-event versus recurrent-event analysis: points to consider for selecting a meaningful analysis strategy in clinical trials with composite endpoints

A comparison of group sequential and fixed sample size designs for bioequivalence trials with highly variable drugs

A systematic comparison of recurrent event models for application to composite endpoints

The Average Hazard Ratio – A Good Effect Measure for Time-to-event Endpoints when the Proportional Hazard Assumption is Violated?

Fallzahlberechnung in der medizinischen Forschung : eine Einführung für Mediziner und Biostatistiker

Fallzahlberechnung in der medizinischen Forschung : Eine Einführung für Mediziner und Biostatistiker

Resting autonomic nervous system activity is unrelated to antisocial behaviour dimensions in adolescents : Cross-sectional findings from a European multi-centre study