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Person

Rolf Backofen (1963-)

Informatiker

Name	Rolf Backofen
Zeit	1963- (Lebensdaten)
Ort	Saarbrücken (Wirkungsort) Jena (Wirkungsort) Freiburg im Breisgau (Wirkungsort) Deutschland
Geschlecht	männlich
Akademischer Grad bzw. Titel	Prof., Dr. rer. nat. habil.
Beruf	Informatiker (charakteristischer Beruf) Bioinformatiker
Beziehung	Deutsches Forschungszentrum für Künstliche Intelligenz Friedrich-Schiller-Universität Jena (2001-2005) Albert-Ludwigs-Universität Freiburg. Institut für Informatik (Leiter) (2010-)
Weitere Angaben	Fachgebiet: Bioinformatik
Quelle	Kürschner Gelehrte 2009 Wikipedia
Datensatztyp	Person
GND-Nummer	1037902459
Datensatz-ID	1037902459
Beteiligt an alle anzeigen Heterogenous nuclear ribonucleoprotein D-like controls endothelial cell functions Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration CheRRI - accurate classification of the biological relevance of putative RNA–RNA interaction sites Deepdefense: annotation of immune systems in prokaryotes using deep learning Heterogenous nuclear ribonucleoprotein D-like controls endothelial cell functions Improved discovery of RNA-binding protein binding sites in eCLIP data using DEWSeq Interrogating two extensively self-targeting Type I CRISPR-Cas systems in Xanthomonas albilineans reveals distinct anti-CRISPR proteins that block DNA degradation Partial RNA design SpacerPlacer: ancestral reconstruction of CRISPR arrays reveals the evolutionary dynamics of spacer deletions The challenges of research data management in cardiovascular science: a DGK and DZHK position paper - executive summary The role of the 5’ sensing function of ribonuclease E in cyanobacteria Workflow recommendations using deep learning and machine learning tools for exploratory and predictive data analysis in Galaxy Transformer-based tool recommendation system in Galaxy The challenges of research data management in cardiovascular science: a DGK and DZHK position paper—executive summary Embedding the de.NBI Cloud in the National Research Data Infrastructure Activities Characterization of the zinc finger μ-protein HVO_0758 from Haloferax volcanii: biological roles, zinc binding, and NMR solution structure Developing a workflow management system for fragment-based virtual screening Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia Meta-analysis of mechano-sensitive ion channels in human hearts: chamber- and disease-preferential mRNA expression Recognition of functional relationships between biomedical concepts in the scientific literature using text mining and machine learning Revealing the small proteome of Haloferax volcaniiby combining ribosome profiling and small-protein optimized mass spectrometry Ribosome profiling reveals the fine-tuned response of Escherichia coli to mild and severe acid stress RNA interaction format: a general data format for RNA interactions The challenges of research data management in cardiovascular science : a DGK and DZHK position paper—executive summary Transformer-based tool recommendation system in Galaxy Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease An accessible infrastructure for artificial intelligence using a Docker-based JupyterLab in Galaxy Approaches to analysis of chromosome conformation capture data Bioinformatic analysis and online database set-up for circular RNAs in non-small cell lung cancer Computational analysis and prediction of RNA-protein interactions CRISPRtracrRNA: robust approach for CRISPR tracrRNA detection Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease Genome wide CRISPR screen for Pasteurella multocida toxin (PMT) binding proteins reveals LDL Receptor Related Protein 1 (LRP1) as crucial cellular receptor High detection rate for disease-causing variants in a cohort of 30 Iranian pediatric steroid resistant nephrotic syndrome cases Loop detection using Hi-C data with HiCExplorer Peakhood: individual site context extraction for CLIP-seq peak regions RiboReport - benchmarking tools for ribosome profiling-based identification of open reading frames in bacteria Spectrum of genetic variants in a cohort of 37 laterality defect cases Standardization of CLIP-seq data analysis and optimization of related peak calling to investigate RNA-protein interactions The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS A SARS-CoV-2 sequence submission tool for the European Nucleotide Archive An integrated database of small RNAs and their interplay with transcriptional gene regulatory networks in corynebacteria Analysis of high-throughput sequencing data related to small non-coding RNAs biogenesis and function Analysis of high-throughput sequencing data related to small non-coding RNAs biogenesis and function CdrS is a global transcriptional regulator influencing cell division in Haloferax volcanii Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration ChiRA: an integrated framework for chimeric read analysis from RNA-RNA interactome and RNA structurome data CRISPRidentify: identification of CRISPR arrays using machine learning approach CRISPRloci: comprehensive and accurate annotation of CRISPR–Cas systems Data analysis for the COVID-19 research: contributions of the German Network of Bioinformatics Infrastructure MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration Publisher correction: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration RNAProt: an efficient and feature-rich RNA binding protein binding site predictor Robust and efficient single-cell Hi-C clustering with approximate k-nearest neighbor graphs Scool: a new data storage format for single-cell Hi-C data StoatyDive: evaluation and classification of peak profiles for sequencing data Structure-aware machine learning identifies microRNAs operating as Toll-like receptor 7/8 ligands Tool recommender system in Galaxy using deep learning

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Katalog der Deutschen Nationalbibliothek

Rolf Backofen (1963-)

Heterogenous nuclear ribonucleoprotein D-like controls endothelial cell functions

Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration

CheRRI - accurate classification of the biological relevance of putative RNA–RNA interaction sites

Deepdefense: annotation of immune systems in prokaryotes using deep learning

Heterogenous nuclear ribonucleoprotein D-like controls endothelial cell functions

Improved discovery of RNA-binding protein binding sites in eCLIP data using DEWSeq

Interrogating two extensively self-targeting Type I CRISPR-Cas systems in Xanthomonas albilineans reveals distinct anti-CRISPR proteins that block DNA degradation

Partial RNA design

SpacerPlacer: ancestral reconstruction of CRISPR arrays reveals the evolutionary dynamics of spacer deletions

The challenges of research data management in cardiovascular science: a DGK and DZHK position paper - executive summary

The role of the 5’ sensing function of ribonuclease E in cyanobacteria

Workflow recommendations using deep learning and machine learning tools for exploratory and predictive data analysis in Galaxy

Transformer-based tool recommendation system in Galaxy

The challenges of research data management in cardiovascular science: a DGK and DZHK position paper—executive summary

Embedding the de.NBI Cloud in the National Research Data Infrastructure Activities

Characterization of the zinc finger μ-protein HVO_0758 from Haloferax volcanii: biological roles, zinc binding, and NMR solution structure

Developing a workflow management system for fragment-based virtual screening

Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia

Meta-analysis of mechano-sensitive ion channels in human hearts: chamber- and disease-preferential mRNA expression

Recognition of functional relationships between biomedical concepts in the scientific literature using text mining and machine learning

Revealing the small proteome of Haloferax volcaniiby combining ribosome profiling and small-protein optimized mass spectrometry

Ribosome profiling reveals the fine-tuned response of Escherichia coli to mild and severe acid stress

RNA interaction format: a general data format for RNA interactions

The challenges of research data management in cardiovascular science : a DGK and DZHK position paper—executive summary

Transformer-based tool recommendation system in Galaxy

Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease

An accessible infrastructure for artificial intelligence using a Docker-based JupyterLab in Galaxy

Approaches to analysis of chromosome conformation capture data

Bioinformatic analysis and online database set-up for circular RNAs in non-small cell lung cancer

Computational analysis and prediction of RNA-protein interactions

CRISPRtracrRNA: robust approach for CRISPR tracrRNA detection

Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease

Genome wide CRISPR screen for Pasteurella multocida toxin (PMT) binding proteins reveals LDL Receptor Related Protein 1 (LRP1) as crucial cellular receptor

High detection rate for disease-causing variants in a cohort of 30 Iranian pediatric steroid resistant nephrotic syndrome cases

Loop detection using Hi-C data with HiCExplorer

Peakhood: individual site context extraction for CLIP-seq peak regions

RiboReport - benchmarking tools for ribosome profiling-based identification of open reading frames in bacteria

Spectrum of genetic variants in a cohort of 37 laterality defect cases

Standardization of CLIP-seq data analysis and optimization of related peak calling to investigate RNA-protein interactions

The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity

MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration

A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS

A SARS-CoV-2 sequence submission tool for the European Nucleotide Archive

An integrated database of small RNAs and their interplay with transcriptional gene regulatory networks in corynebacteria

Analysis of high-throughput sequencing data related to small non-coding RNAs biogenesis and function

Analysis of high-throughput sequencing data related to small non-coding RNAs biogenesis and function

CdrS is a global transcriptional regulator influencing cell division in Haloferax volcanii

Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration

ChiRA: an integrated framework for chimeric read analysis from RNA-RNA interactome and RNA structurome data

CRISPRidentify: identification of CRISPR arrays using machine learning approach

CRISPRloci: comprehensive and accurate annotation of CRISPR–Cas systems

Data analysis for the COVID-19 research: contributions of the German Network of Bioinformatics Infrastructure

MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration

Publisher correction: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration

RNAProt: an efficient and feature-rich RNA binding protein binding site predictor

Robust and efficient single-cell Hi-C clustering with approximate k-nearest neighbor graphs

Scool: a new data storage format for single-cell Hi-C data

StoatyDive: evaluation and classification of peak profiles for sequencing data

Structure-aware machine learning identifies microRNAs operating as Toll-like receptor 7/8 ligands

Tool recommender system in Galaxy using deep learning