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Thorsten Friedrich

Biochemiker

Name	Thorsten Friedrich
Ort	Freiburg im Breisgau (Wirkungsort) Deutschland
Geschlecht	männlich
Akademischer Grad bzw. Titel	Prof. Dr.
Beruf	Biochemiker (charakteristischer Beruf)
Variante	T. Friedrich
Weitere Angaben	Univ. Freiburg, Fakultät für Chemie und Pharmazie, Institut für Biochemie
Datensatztyp	Person
GND-Nummer	1071609173
Datensatz-ID	1071609173
Beteiligt an alle anzeigen On the mechanism of Escherichia coli respiratory complex I Quinone chemistry in respiratory complex I involves protonation of a conserved aspartic acid residue Structural robustness of the NADH binding site in NADH:ubiquinone oxidoreductase (complex I) Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D Structures of 3-acetylpyridine adenine dinucleotide and ADP-ribose bound to the electron input module of respiratory complex I Trapping the substrate radical of heme synthase AhbD Exploring ND-011992, a quinazoline-type inhibitor targeting quinone reductases and quinol oxidases Deciphering mechanisms of respiratory chain complexes by IR labelling and surface enhanced approaches Insights into the cellular role of mammalian inositol pyrophosphates Structure of NuoEF variants for the analysis of NADH binding by respiratory complex I Struktur und Funktion der Ubichinol:Sauerstoff Cytochrom bd-II Oxidoreduktase aus Escherichia coli Thallide: Synthese, Kristallchemie und chemische Bindung The Radical SAM heme synthase AhbD from Methanosarcina barkeri contains two auxiliary [4Fe-4S] clusters A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique C α ‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique C α ‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase A cobalamin‐dependent radical SAM enzyme catalyzes the unique Cα‐methylation of glutamine in methyl‐coenzyme M reductase Characterisation of the redox centers of ethylbenzene dehydrogenase Charakterisierung der Eisen-Schwefel-Cluster der Häm-Synthase AhbD aus Methanosarcina barkeri Energetic coupling of electron transfer processes in a syntrophic fatty acid degrader Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis Recent advances in structural studies of cytochrome bd and its potential application as a drug target Respiratory complex I with charge symmetry in the membrane arm pumps protons The clinically relevant triple mutation in the mtND1 gene inactivates Escherichia coli complex I Über den Mechanismus der Protonentranslokation im respiratorischen Komplex I Characterisation of the redox centers of ethylbenzene dehydrogenase Structural Basis for Inhibition of ROS‐Producing Respiratory Complex I by NADH‐OH Structural Basis for Inhibition of ROS‐Producing Respiratory Complex I by NADH‐OH A quinol anion as catalytic intermediate coupling proton translocation with electron transfer in E. coli respiratory complex I Biochemical consequences of two clinically relevant ND-gene mutations in Escherichia coli respiratory complex I Involvement of tyrosines 114 and 139 of subunit NuoB in the proton pathway around cluster N2 in Escherichia coli NADH:ubiquinone oxidoreductase Mass photometry of membrane proteins Structural basis for inhibition of ROS‐producing respiratory complex I by NADH‐OH Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D The inhibition study of cytochrome bd oxidase using the enzyme-based electrochemical sensor Quantifying the heterogeneity of macromolecular machines by mass photometry Stabilization of the highly hydrophobic membrane protein, cytochrome bd oxidase, on metallic surfaces for direct electrochemical studies Structure of the ubiquinol:oxygen cytochrome bd-I oxidoreductase from Escherichia coli The long Q-loop of Escherichia coli cytochrome bd oxidase is required for assembly and structural integrity The N‐terminal domains of the paralogous HycE and NuoCD<br>govern assembly of the respective formate hydrogenlyase and<br>NADH dehydrogenase complexes Towards the structure of complex I and bo3 oxidase from Escherichia coli and exploring its aerobic respiratory chain A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I Homologous bd oxidases share the same architecture but differ in mechanism Low cost, microcontroller based heating device for multi-wavelength differential scanning fluorimetry Low cost, microcontroller based heating device for multi-wavelength differential scanning fluorimetry Strukturelle Untersuchung der NADH Oxidation durch NuoEF The mechanism of NADH oxidation by respiratory complex I with focus on the production of reactive oxygen species Reduction of the off-pathway iron-sulphur cluster N1a of Escherichia coli respiratory complex I restrains NAD+ dissociation Reduction of the off-pathway iron-sulphur cluster N1a of Escherichia coli respiratory complex I restrains NAD+ dissociation Über die Assemblierung des respiratorischen Komplex I in Escherichia coli Wide distribution of foxicin biosynthetic gene clusters in streptomyces strains - an unusual secondary metabolite with various properties Assembly of the Escherichia coli NADH:ubiquinone oxidoreductase (respiratory complex I) Cytochrome bd displays significant quinol peroxidase activity Production, purification and characterization of the cytochrome bd ubiquinol oxidase from Escherichia coli and Aquifex aeolicus Redox cofactors insertion in prokaryotic molybdoenzymes occurs via a conserved folding mechanism Studies on the Escherichia coli aerobic respiratory chain with an emphasis on complex I Electron Tunneling Rates in Respiratory Complex I Are Tuned for Efficient Energy Conversion † Charakterisierung der Aktin- und Rho-modifizierenden Toxine PTC3 und PTC5 aus Photorhabdus luminescens Electron tunneling rates in respiratory complex I are tuned for efficient energy conversion Untersuchungen zur Funktion und Bedeutung von Tyrosin204 und Cystein206 bei der Bildung von reaktiven Sauerstoffspezies an Komplex I

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Katalog der Deutschen Nationalbibliothek

Thorsten Friedrich

On the mechanism of Escherichia coli respiratory complex I

Quinone chemistry in respiratory complex I involves protonation of a conserved aspartic acid residue

Structural robustness of the NADH binding site in NADH:ubiquinone oxidoreductase (complex I)

Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D

Structures of 3-acetylpyridine adenine dinucleotide and ADP-ribose bound to the electron input module of respiratory complex I

Trapping the substrate radical of heme synthase AhbD

Exploring ND-011992, a quinazoline-type inhibitor targeting quinone reductases and quinol oxidases

Deciphering mechanisms of respiratory chain complexes by IR labelling and surface enhanced approaches

Insights into the cellular role of mammalian inositol pyrophosphates

Structure of NuoEF variants for the analysis of NADH binding by respiratory complex I

Struktur und Funktion der Ubichinol:Sauerstoff Cytochrom bd-II Oxidoreduktase aus Escherichia coli

Thallide: Synthese, Kristallchemie und chemische Bindung

The Radical SAM heme synthase AhbD from Methanosarcina barkeri contains two auxiliary [4Fe-4S] clusters

A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique C α ‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase

A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique C α ‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase

A cobalamin‐dependent radical SAM enzyme catalyzes the unique Cα‐methylation of glutamine in methyl‐coenzyme M reductase

Characterisation of the redox centers of ethylbenzene dehydrogenase

Charakterisierung der Eisen-Schwefel-Cluster der Häm-Synthase AhbD aus Methanosarcina barkeri

Energetic coupling of electron transfer processes in a syntrophic fatty acid degrader

Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis

Recent advances in structural studies of cytochrome bd and its potential application as a drug target

Respiratory complex I with charge symmetry in the membrane arm pumps protons

The clinically relevant triple mutation in the mtND1 gene inactivates Escherichia coli complex I

Über den Mechanismus der Protonentranslokation im respiratorischen Komplex I

Characterisation of the redox centers of ethylbenzene dehydrogenase

Structural Basis for Inhibition of ROS‐Producing Respiratory Complex I by NADH‐OH

Structural Basis for Inhibition of ROS‐Producing Respiratory Complex I by NADH‐OH

A quinol anion as catalytic intermediate coupling proton translocation with electron transfer in E. coli respiratory complex I

Biochemical consequences of two clinically relevant ND-gene mutations in Escherichia coli respiratory complex I

Involvement of tyrosines 114 and 139 of subunit NuoB in the proton pathway around cluster N2 in Escherichia coli NADH:ubiquinone oxidoreductase

Mass photometry of membrane proteins

Structural basis for inhibition of ROS‐producing respiratory complex I by NADH‐OH

Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D

The inhibition study of cytochrome bd oxidase using the enzyme-based electrochemical sensor

Quantifying the heterogeneity of macromolecular machines by mass photometry

Stabilization of the highly hydrophobic membrane protein, cytochrome bd oxidase, on metallic surfaces for direct electrochemical studies

Structure of the ubiquinol:oxygen cytochrome bd-I oxidoreductase from Escherichia coli

The long Q-loop of Escherichia coli cytochrome bd oxidase is required for assembly and structural integrity

The N‐terminal domains of the paralogous HycE and NuoCD<br>govern assembly of the respective formate hydrogenlyase and<br>NADH dehydrogenase complexes

Towards the structure of complex I and bo3 oxidase from Escherichia coli and exploring its aerobic respiratory chain

A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I

A mechanism to prevent production of reactive oxygen species by Escherichia coli respiratory complex I

Homologous bd oxidases share the same architecture but differ in mechanism

Low cost, microcontroller based heating device for multi-wavelength differential scanning fluorimetry

Low cost, microcontroller based heating device for multi-wavelength differential scanning fluorimetry

Strukturelle Untersuchung der NADH Oxidation durch NuoEF

The mechanism of NADH oxidation by respiratory complex I with focus on the production of reactive oxygen species

Reduction of the off-pathway iron-sulphur cluster N1a of Escherichia coli respiratory complex I restrains NAD+ dissociation

Reduction of the off-pathway iron-sulphur cluster N1a of Escherichia coli respiratory complex I restrains NAD+ dissociation

Über die Assemblierung des respiratorischen Komplex I in Escherichia coli

Wide distribution of foxicin biosynthetic gene clusters in streptomyces strains - an unusual secondary metabolite with various properties

Assembly of the Escherichia coli NADH:ubiquinone oxidoreductase (respiratory complex I)

Cytochrome bd displays significant quinol peroxidase activity

Production, purification and characterization of the cytochrome bd ubiquinol oxidase from Escherichia coli and Aquifex aeolicus

Redox cofactors insertion in prokaryotic molybdoenzymes occurs via a conserved folding mechanism

Studies on the Escherichia coli aerobic respiratory chain with an emphasis on complex I

Electron Tunneling Rates in Respiratory Complex I Are Tuned for Efficient Energy Conversion †

Charakterisierung der Aktin- und Rho-modifizierenden Toxine PTC3 und PTC5 aus Photorhabdus luminescens

Electron tunneling rates in respiratory complex I are tuned for efficient energy conversion

Untersuchungen zur Funktion und Bedeutung von Tyrosin204 und Cystein206 bei der Bildung von reaktiven Sauerstoffspezies an Komplex I