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Hartmut Hengel (1960-)

Arzt

Name	Hartmut Hengel
Zeit	1960- (Lebensdaten)
Ort	Aalen (Geburtsort) Freiburg im Breisgau (Wirkungsort) Deutschland
Akademischer Grad bzw. Titel	Prof. Dr.
Beruf	Arzt (charakteristischer Beruf)
Beziehung	Institut für Virologie (Freiburg im Breisgau) (Oktober 2012-) Virologie (Thema) Medizinische Mikrobiologie (Thema)
Datensatztyp	Person
GND-Nummer	1133388795
Datensatz-ID	1133388795
Beteiligt an alle anzeigen Arsenic trioxide impacts hepatitis B virus core nuclear localization and efficiently interferes with HBV infection Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids In vitro profiling of the antiviral peptide TAT-I24 Informing pandemic management in Germany with trustworthy, living evidence syntheses and guideline development: lessons learned from the COVID-19 evidence ecosystem (CEOsys) Inhibition of B cell receptor signaling induced by the human adenovirus species D E3/49K protein Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells Test accuracy of rapid diagnostic tests and reverse‐transcription polymerase chain reaction against virus isolation in cell culture for assessing SARS‐CoV‐2 infectivity: systematic review and meta‐analysis Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination Corrigendum: Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency? Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulation Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus Meningitis without rash after reactivation of varicella vaccine strain in a 12-year-old immunocompetent boy Skin manifestations after immunisation with an adjuvanted recombinant zoster vaccine, Germany, 2020 Tiza–Titre increase and enhanced immunity through an adjuvanted, recombinant herpes zoster subunit vaccine in patients with liver cirrhosis and post-liver transplantation: a study protocol for a prospective cohort study Circulating multimeric immune complexes contribute to immunopathology in COVID-19 Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies Assessing severe acute respiratory syndrome coronavirus 2 infectivity by reverse‐transcription polymerase chain reaction: a systematic review and meta‐analysis Circulating multimeric immune complexes contribute to immunopathology in COVID-19 Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency? Early and rapid identification of COVID-19 patients with neutralizing type I interferon auto-antibodies Robust and durable serological response following pediatric SARS-CoV-2 infection The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors Untersuchung von Laborparametern bei Varizella Zoster Virus-Infektionen des zentralen Nervensystems im Rahmen eines Herpes Zoster Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel Cytomegalovirus restricts ICOSL expression on antigen-presenting cells disabling T cell co-stimulation and contributing to immune evasion Human cytomegalovirus antagonizes activation of Fcγ receptors by distinct and synergizing modes of IgG manipulation Prevalence of SARS-CoV-2 infection in children and their parents in Southwest Germany The Fcγ-binding glycoprotein gp34 of Human cytomegalovirus targets IgG switched memory B cells to mediate humoral immune evasion The peptide TAT-I24 with antiviral activity against DNA viruses binds double-stranded DNA with high affinity Trigger‐dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis A novel, broad-acting peptide inhibitor of double-stranded DNA virus gene expression and replication A novel, broad-acting peptide inhibitor of double-stranded DNA virus gene expression and replication COVID-19 in a severely immunosuppressed patient with life-threatening eosinophilic granulomatosis with polyangiitis COVID-19 in-hospital mortality and mode of death in a dynamic and non-restricted tertiary care model in Germany HCMV infection in a mesenchymal stem cell niche: differential impact on the development of NK cells versus ILC3 Identification of HCMV-derived T cell epitopes in seropositive individuals through viral deletion models Pharmacological inhibition of acid sphingomyelinase prevents uptake of SARS-CoV-2 by epithelial cells The human cytomegalovirus pUL145 isoforms act as viral DDB1-cullin-associated factors to instruct host protein degradation to impede innate immunity Trigger‐dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11 Selective engagement of Fc[gamma]RIV by a M2e-specific single domain antibody construct protects against influenza A virus infection The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors Influence of demographic changes on the impact of vaccination against varicella and herpes zoster in Germany – a mathematical modelling study Anti-inflammatory consequences of bile acid accumulation in virus-infected bile duct ligated mice Influence of demographic changes on the impact of vaccination against varicella and herpes zoster in Germany – a mathematical modelling study A highly conserved sequence of the viral TAP inhibitor ICP47 is required for freezing of the peptide transport cycle Antibody cross-reactivity between Porcine Cytomegalovirus (PCMV) and Human Herpesvirus-6 (HHV-6) Antibody Cross-Reactivity between Porcine Cytomegalovirus (PCMV) and Human Herpesvirus-6 (HHV-6) Elusive role of the CD94/NKG2C NK cell receptor in the response to cytomegalovirus: novel experimental observations in a reporter cell system Identification of a genetic variation in ERAP1 aminopeptidase that prevents human cytomegalovirus miR-UL112-5p-mediated immunoevasion Dynamic co-evolution of host and pathogen: HCMV downregulates the prevalent allele MICA∗008 to escape elimination by NK cells A Cytomegalovirus Inhibitor of Gamma Interferon Signaling Controls Immunoproteasome Induction Mikrobiologie und Immunologie : Kurzlehrbuch zum GK 2 ; mit 76 Tabellen Mikrobiologie und Immunologie : Kurzlehrbuch zum GK 2 Mikrobiologie und Immunologie : Kurzlehrbuch zum Gegenstandskatalog 2 Repertoirestudien muriner zytotoxischer T-Lymphozyten mit Hilfe des Modellantigens Herpes simplex Virus (HSV)

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Katalog der Deutschen Nationalbibliothek

Hartmut Hengel (1960-)

Arsenic trioxide impacts hepatitis B virus core nuclear localization and efficiently interferes with HBV infection

Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids

In vitro profiling of the antiviral peptide TAT-I24

Informing pandemic management in Germany with trustworthy, living evidence syntheses and guideline development: lessons learned from the COVID-19 evidence ecosystem (CEOsys)

Inhibition of B cell receptor signaling induced by the human adenovirus species D E3/49K protein

Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning

Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells

Test accuracy of rapid diagnostic tests and reverse‐transcription polymerase chain reaction against virus isolation in cell culture for assessing SARS‐CoV‐2 infectivity: systematic review and meta‐analysis

Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination

Corrigendum: Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency?

Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulation

Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus

Meningitis without rash after reactivation of varicella vaccine strain in a 12-year-old immunocompetent boy

Skin manifestations after immunisation with an adjuvanted recombinant zoster vaccine, Germany, 2020

Tiza–Titre increase and enhanced immunity through an adjuvanted, recombinant herpes zoster subunit vaccine in patients with liver cirrhosis and post-liver transplantation: a study protocol for a prospective cohort study

Circulating multimeric immune complexes contribute to immunopathology in COVID-19

Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies

Assessing severe acute respiratory syndrome coronavirus 2 infectivity by reverse‐transcription polymerase chain reaction: a systematic review and meta‐analysis

Circulating multimeric immune complexes contribute to immunopathology in COVID-19

Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel

Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency?

Early and rapid identification of COVID-19 patients with neutralizing type I interferon auto-antibodies

Robust and durable serological response following pediatric SARS-CoV-2 infection

The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors

Untersuchung von Laborparametern bei Varizella Zoster Virus-Infektionen des zentralen Nervensystems im Rahmen eines Herpes Zoster

Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel

Cytomegalovirus restricts ICOSL expression on antigen-presenting cells disabling T cell co-stimulation and contributing to immune evasion

Human cytomegalovirus antagonizes activation of Fcγ receptors by distinct and synergizing modes of IgG manipulation

Prevalence of SARS-CoV-2 infection in children and their parents in Southwest Germany

The Fcγ-binding glycoprotein gp34 of Human cytomegalovirus targets IgG switched memory B cells to mediate humoral immune evasion

The peptide TAT-I24 with antiviral activity against DNA viruses binds double-stranded DNA with high affinity

Trigger‐dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis

A novel, broad-acting peptide inhibitor of double-stranded DNA virus gene expression and replication

A novel, broad-acting peptide inhibitor of double-stranded DNA virus gene expression and replication

COVID-19 in a severely immunosuppressed patient with life-threatening eosinophilic granulomatosis with polyangiitis

COVID-19 in-hospital mortality and mode of death in a dynamic and non-restricted tertiary care model in Germany

HCMV infection in a mesenchymal stem cell niche: differential impact on the development of NK cells versus ILC3

Identification of HCMV-derived T cell epitopes in seropositive individuals through viral deletion models

Pharmacological inhibition of acid sphingomyelinase prevents uptake of SARS-CoV-2 by epithelial cells

The human cytomegalovirus pUL145 isoforms act as viral DDB1-cullin-associated factors to instruct host protein degradation to impede innate immunity

Trigger‐dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis

HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11

Selective engagement of Fc[gamma]RIV by a M2e-specific single domain antibody construct protects against influenza A virus infection

The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors

Influence of demographic changes on the impact of vaccination against varicella and herpes zoster in Germany – a mathematical modelling study

Anti-inflammatory consequences of bile acid accumulation in virus-infected bile duct ligated mice

Influence of demographic changes on the impact of vaccination against varicella and herpes zoster in Germany – a mathematical modelling study

A highly conserved sequence of the viral TAP inhibitor ICP47 is required for freezing of the peptide transport cycle

Antibody cross-reactivity between Porcine Cytomegalovirus (PCMV) and Human Herpesvirus-6 (HHV-6)

Antibody Cross-Reactivity between Porcine Cytomegalovirus (PCMV) and Human Herpesvirus-6 (HHV-6)

Elusive role of the CD94/NKG2C NK cell receptor in the response to cytomegalovirus: novel experimental observations in a reporter cell system

Identification of a genetic variation in ERAP1 aminopeptidase that prevents human cytomegalovirus miR-UL112-5p-mediated immunoevasion

Dynamic co-evolution of host and pathogen: HCMV downregulates the prevalent allele MICA∗008 to escape elimination by NK cells

A Cytomegalovirus Inhibitor of Gamma Interferon Signaling Controls Immunoproteasome Induction

Mikrobiologie und Immunologie : Kurzlehrbuch zum GK 2 ; mit 76 Tabellen

Mikrobiologie und Immunologie : Kurzlehrbuch zum GK 2

Mikrobiologie und Immunologie : Kurzlehrbuch zum Gegenstandskatalog 2

Repertoirestudien muriner zytotoxischer T-Lymphozyten mit Hilfe des Modellantigens Herpes simplex Virus (HSV)