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Lars G. Fritsche

Name	Lars G. Fritsche
Ort	Deutschland USA
Geschlecht	männlich
Beziehung	Universität Regensburg University of Michigan Biostatistik (Thema) Humangenetik (Thema)
Datensatztyp	Person
GND-Nummer	1159513724
Datensatz-ID	1159513724
Beteiligt an alle anzeigen Improving prediction models of amyotrophic lateral sclerosis (ALS) using polygenic, pre-existing conditions, and survey-based risk scores in the UK Biobank A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans Incorporating functional annotation with bilevel continuous shrinkage for polygenic risk prediction Correction: Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration—the PINNACLE trial protocol Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration—the PINNACLE trial protocol Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies Biobank-driven genomic discovery yields new insight into atrial fibrillation biology Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

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Lars G. Fritsche

Improving prediction models of amyotrophic lateral sclerosis (ALS) using polygenic, pre-existing conditions, and survey-based risk scores in the UK Biobank

A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans

Incorporating functional annotation with bilevel continuous shrinkage for polygenic risk prediction

Correction: Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration—the PINNACLE trial protocol

Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease

Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT

Developing and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration—the PINNACLE trial protocol

Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease

Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease

Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis

Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes