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Brenda A. Schulman (1967-)

Biochemikerin

Name	Brenda A. Schulman
Zeit	1967- (Lebensdaten)
Ort	USA Deutschland
Geschlecht	weiblich
Akademischer Grad bzw. Titel	Dr.
Beruf	Biochemikerin (charakteristischer Beruf)
Variante	Brenda Schulman
Beziehung	Technische Universität München. Fakultät für Chemie (2018-) Max-Planck-Institut für Biochemie Louis-Jeantet Preis für Medizin (Auszeichnung) (2023)
Quelle	Homepage: https://www.mpg.de/11388940 (Stand: 24.04.2023)
Datensatztyp	Person
GND-Nummer	1178346463
Datensatz-ID	1178346463
Beteiligt an alle anzeigen Ubiquitin is a chemist’s playground Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2 Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation Noncanonical assembly, neddylation and chimeric cullin–RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex Visualizing chaperone-mediated multistep assembly of the human 20S proteasome Combinatorial selective ER-phagy remodels the ER during neurogenesis Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE Determining the ubiquitylation mechanism of UBR5 Profiling cellular E3 ubiquitin ligase networks Insights into the ISG15 transfer cascade by the UBE1L activating enzyme Activity-based profiling of cullin–RING E3 networks by conformation-specific probes Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5 A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems A pro-fluorescent ubiquitin-based probe to monitor cysteine-based E3 ligase activity Exploring the Atypical Mechanisms of Protein Ubiquitination by Ariadne E3 Ligases An expanded lexicon for the ubiquitin code Structure of CRL7FBXW8 reveals coupling with CUL1–RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters Cryo-EM structure of CUL5-ARIH2 E3-E3 ligase complex reveals novel allosteric NEDD8 mechanism Mechanisms of polyubiquitin chain formation Mechanistic studies of GID/CTLH E3 ubiquitin ligases NEDD8 orchestrates active ubiquitylation assembly of cullin-RING E3 ligase Structural and functional characterization of GID/CTLH E3 ubiquitin ligases Visualization of structural intermediates in an E3-E3 ligase ubiquitylation cascade via cryo-EM Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63-branched ubiquitin chains The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity Integrative proteomics reveals principles of dynamic phosphosignaling networks in human erythropoiesis Quantifying the heterogeneity of macromolecular machines by mass photometry The instability of the BTB-KELCH protein Gigaxonin causes Giant Axonal Neuropathy and constitutes a new penetrant and specific diagnostic test

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Katalog der Deutschen Nationalbibliothek

Brenda A. Schulman (1967-)

Ubiquitin is a chemist’s playground

Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2

Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation

Noncanonical assembly, neddylation and chimeric cullin–RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex

Visualizing chaperone-mediated multistep assembly of the human 20S proteasome

Combinatorial selective ER-phagy remodels the ER during neurogenesis

Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases

Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE

Determining the ubiquitylation mechanism of UBR5

Profiling cellular E3 ubiquitin ligase networks

Insights into the ISG15 transfer cascade by the UBE1L activating enzyme

Activity-based profiling of cullin–RING E3 networks by conformation-specific probes

Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5

A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity

A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity

PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems

A pro-fluorescent ubiquitin-based probe to monitor cysteine-based E3 ligase activity

Exploring the Atypical Mechanisms of Protein Ubiquitination by Ariadne E3 Ligases

An expanded lexicon for the ubiquitin code

Structure of CRL7FBXW8 reveals coupling with CUL1–RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation

A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters

Cryo-EM structure of CUL5-ARIH2 E3-E3 ligase complex reveals novel allosteric NEDD8 mechanism

Mechanisms of polyubiquitin chain formation

Mechanistic studies of GID/CTLH E3 ubiquitin ligases

NEDD8 orchestrates active ubiquitylation assembly of cullin-RING E3 ligase

Structural and functional characterization of GID/CTLH E3 ubiquitin ligases

Visualization of structural intermediates in an E3-E3 ligase ubiquitylation cascade via cryo-EM

Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology

The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains

The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63-branched ubiquitin chains

The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains

Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

Integrative proteomics reveals principles of dynamic phosphosignaling networks in human erythropoiesis

Quantifying the heterogeneity of macromolecular machines by mass photometry

The instability of the BTB-KELCH protein Gigaxonin causes Giant Axonal Neuropathy and constitutes a new penetrant and specific diagnostic test