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Harald Kolmar

Biochemiker

Name	Harald Kolmar
Ort	Deutschland
Akademischer Grad bzw. Titel	Prof. Dr.
Beruf	Biochemiker (charakteristischer Beruf)
Beziehung	Technische Universität Darmstadt. Fachbereich Chemie Biochemie (Studienfach)
Quelle	Webseite: https://www.chemie.tu-darmstadt.de/forschung_5/arbeitsgruppen/alleprofessoren/professoren_einzelansicht_289.de.jsp (Stand: 25.10.19)
Datensatztyp	Person
GND-Nummer	1197913467
Datensatz-ID	1197913467
Beteiligt an alle anzeigen 3D topographies promote macrophage M2d-Subset differentiation A Bioorthogonal Click Chemistry Toolbox for Targeted Synthesis of Branched and Well-Defined Protein–Protein Conjugates A Conditionally Activated Cytosol-Penetrating Antibody for TME-Dependent Intracellular Cargo Delivery Artificial cell synthesis using biocatalytic polymerization-induced self-assembly Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1 Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format Characterization of lipoprotein supplement and influence of its oxidized lipid content on cell culture performance and monoclonal antibody production by a SP2/0 hybridoma cell line Conditional activation of an anti-IgM antibody-drug conjugate for precise B cell lymphoma targeting Dextramabs: A Novel Format of Antibody-Drug Conjugates Featuring a Multivalent Polysaccharide Scaffold Discovery and Characterization of Allosteric Antibodies Engineering of ultraID, a compact and hyperactive enzyme for proximity-dependent biotinylation in living cells Exploration of Metagenomic Racemases for Biosynthetic Cascades Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition Parahydrogen-induced polarization allows 2000-fold signal enhancement in biologically active derivatives of the peptide-based drug octreotide Proximity-based screening of a class A/B hybrid G protein-coupled receptor Respiratory syncytial virus–approved mAb Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors S-Sulfocysteine – Investigation of cellular uptake in CHO cells Self-decorating cells via surface-initiated enzymatic controlled radical polymerization Sustainable Peptide Synthesis Enabled by a Transient Protecting Group Use of 5-Thio-L-Fucose to modulate binding affinity of therapeutic proteins Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features Anti-idiotype antibodies for biomedical applications Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features Characterization of soy protein hydrolysates and influence of its iron content on monoclonal antibody production by a murine hybridoma cell line Conditional Cell Penetration of a Masked CPP and Optimization of Multimeric CPP-Delivery Modules for Intracellular Cargo Delivery Covalent Attachment of Enzymes to Paper Fibers for Paper-Based Analytical Devices Development of Innovative Bioconjugation Strategies for the Generation of Bi-Specific Antibodies Enabling Targeted Protein Degradation Dual Function pH Responsive Bispecific Antibodies for Tumor Targeting and Antigen Depletion in Plasma EGFR binding Fc domain-drug conjugates: stable and highly potent cytotoxic molecules mediate selective cell killing Engineering IgG-Like Bispecific Antibodies — An Overview Explorations towards the biocatalytic synthesis of a hazelnut aroma precursor Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteins Functionality-Enhanced Antibodies for Precision Cancer Therapy Generation of a host cell line containing a MAR-rich landing pad for site-specific integration and expression of transgenes Humanization of Chicken‐Derived scFv Using Yeast Surface Display and NGS Data Mining Identification of novel antagonists against skin relevant molecular targets in mediation of itch and inflammation Intein mediated high throughput screening for bispecific antibodies Isolation of Common Light Chain Antibodies from Immunized Chickens Using Yeast Biopanning and Fluorescence‐Activated Cell Sorting Macrophages Cell Surface Proteome Analysis for Identification of Markers and Therapeutic Targets Merge Two into One: Multispecific Symmetric Antibodies for Cancer Immunotherapy Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity Mimicking the immunosuppressive impact of fibroblasts in a 3D multicellular spheroid model Modifikation von Proteinen mittels Photosensibilisatoren für die strukturierte Proteinimmobilisierung und Quervernetzung von Biomaterialien Modulation of the FKBP51 structure by protein engineering and isolation of conformation-locking antibodies and affibodies Multivalent dextran hybrids for efficient cytosolic delivery of biomolecular cargoes Optimierung der Astaxanthin-Synthese in Synechococcus sp. PCC7002 unter Zuhilfenahme synthetischer Biologie Penetration of Nanobody-Dextran Polymer Conjugates through Tumor Spheroids Peptide und Peptoide als Bindepartner für Chemokine Potent Apoptosis Induction by a Novel Trispecific B7-H3xCD16xTIGIT 2+1 Common Light Chain Natural Killer Cell Engager REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells Recombinant Antibody Production Using a Dual-Promoter Single Plasmid System Refined generation of chimeric antigen receptor T cells by dasatinib and urolithin A Review: High temperature short time treatment of cell culture media and feed solutions to mitigate adventitious viral contamination in the biopharmaceutical industry Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies Tag-free, specific conjugation of glycosylated IgG1 antibodies using microbial transglutaminase Targeted Phagocytosis Induction for Cancer Immunotherapy via Bispecific MerTK-Engaging Antibodies

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Katalog der Deutschen Nationalbibliothek

Harald Kolmar

3D topographies promote macrophage M2d-Subset differentiation

A Bioorthogonal Click Chemistry Toolbox for Targeted Synthesis of Branched and Well-Defined Protein–Protein Conjugates

A Conditionally Activated Cytosol-Penetrating Antibody for TME-Dependent Intracellular Cargo Delivery

Artificial cell synthesis using biocatalytic polymerization-induced self-assembly

Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1

Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities

Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format

Characterization of lipoprotein supplement and influence of its oxidized lipid content on cell culture performance and monoclonal antibody production by a SP2/0 hybridoma cell line

Conditional activation of an anti-IgM antibody-drug conjugate for precise B cell lymphoma targeting

Dextramabs: A Novel Format of Antibody-Drug Conjugates Featuring a Multivalent Polysaccharide Scaffold

Discovery and Characterization of Allosteric Antibodies

Engineering of ultraID, a compact and hyperactive enzyme for proximity-dependent biotinylation in living cells

Exploration of Metagenomic Racemases for Biosynthetic Cascades

Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition

Parahydrogen-induced polarization allows 2000-fold signal enhancement in biologically active derivatives of the peptide-based drug octreotide

Proximity-based screening of a class A/B hybrid G protein-coupled receptor

Respiratory syncytial virus–approved mAb Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors

S-Sulfocysteine – Investigation of cellular uptake in CHO cells

Self-decorating cells via surface-initiated enzymatic controlled radical polymerization

Sustainable Peptide Synthesis Enabled by a Transient Protecting Group

Use of 5-Thio-L-Fucose to modulate binding affinity of therapeutic proteins

Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features

Anti-idiotype antibodies for biomedical applications

Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies

Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies

Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features

Characterization of soy protein hydrolysates and influence of its iron content on monoclonal antibody production by a murine hybridoma cell line

Conditional Cell Penetration of a Masked CPP and Optimization of Multimeric CPP-Delivery Modules for Intracellular Cargo Delivery

Covalent Attachment of Enzymes to Paper Fibers for Paper-Based Analytical Devices

Development of Innovative Bioconjugation Strategies for the Generation of Bi-Specific Antibodies Enabling Targeted Protein Degradation

Dual Function pH Responsive Bispecific Antibodies for Tumor Targeting and Antigen Depletion in Plasma

EGFR binding Fc domain-drug conjugates: stable and highly potent cytotoxic molecules mediate selective cell killing

Engineering IgG-Like Bispecific Antibodies — An Overview

Explorations towards the biocatalytic synthesis of a hazelnut aroma precursor

Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteins

Functionality-Enhanced Antibodies for Precision Cancer Therapy

Generation of a host cell line containing a MAR-rich landing pad for site-specific integration and expression of transgenes

Humanization of Chicken‐Derived scFv Using Yeast Surface Display and NGS Data Mining

Identification of novel antagonists against skin relevant molecular targets in mediation of itch and inflammation

Intein mediated high throughput screening for bispecific antibodies

Isolation of Common Light Chain Antibodies from Immunized Chickens Using Yeast Biopanning and Fluorescence‐Activated Cell Sorting

Macrophages Cell Surface Proteome Analysis for Identification of Markers and Therapeutic Targets

Merge Two into One: Multispecific Symmetric Antibodies for Cancer Immunotherapy

Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity

Mimicking the immunosuppressive impact of fibroblasts in a 3D multicellular spheroid model

Modifikation von Proteinen mittels Photosensibilisatoren für die strukturierte Proteinimmobilisierung und Quervernetzung von Biomaterialien

Modulation of the FKBP51 structure by protein engineering and isolation of conformation-locking antibodies and affibodies

Multivalent dextran hybrids for efficient cytosolic delivery of biomolecular cargoes

Optimierung der Astaxanthin-Synthese in Synechococcus sp. PCC7002 unter Zuhilfenahme synthetischer Biologie

Penetration of Nanobody-Dextran Polymer Conjugates through Tumor Spheroids

Peptide und Peptoide als Bindepartner für Chemokine

Potent Apoptosis Induction by a Novel Trispecific B7-H3xCD16xTIGIT 2+1 Common Light Chain Natural Killer Cell Engager

REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells

Recombinant Antibody Production Using a Dual-Promoter Single Plasmid System

Refined generation of chimeric antigen receptor T cells by dasatinib and urolithin A

Review: High temperature short time treatment of cell culture media and feed solutions to mitigate adventitious viral contamination in the biopharmaceutical industry

Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries

Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies

Tag-free, specific conjugation of glycosylated IgG1 antibodies using microbial transglutaminase

Targeted Phagocytosis Induction for Cancer Immunotherapy via Bispecific MerTK-Engaging Antibodies