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Stefan Hüttelmaier (1973-)

Cytologe

Name	Stefan Hüttelmaier
Zeit	1973- (Lebensdaten)
Ort	Halle (Saale) (Wirkungsort) Braunschweig (Wirkungsort) Deutschland
Akademischer Grad bzw. Titel	Prof. Dr.
Beruf	Cytologe (charakteristischer Beruf)
Beziehung	Martin-Luther-Universität Halle-Wittenberg. Medizinische Fakultät
Weitere Angaben	Diss., Fachbereich Naturwissenschaften, Biotechnologie
Quelle	https://www.medizin.uni-halle.de/index.php?id=817 (Stand: 18.05.2020)
Datensatztyp	Person
GND-Nummer	122419065
Datensatz-ID	122419065
Beteiligt an alle anzeigen Development of new pyrazoles as class I HDAC inhibitors: Synthesis, molecular modeling, and biological characterization in leukemia cells Utilization of an optimized AlphaFold protein model for structure‐based design of a selective HDAC11 inhibitor with anti‐neuroblastoma activity Das RNA-bindende Protein RAVER1 moduliert die miR/RISC-Aktivität und TGFβ-abhängige EMT durch Regulation des alternativen Spleißens Deciphering the role of LINC00261 and FOXA2 in epithelial-mesenchymal transition and metastasis of pancreatic cancer cells From sequencing to function : a triad of RNA-guided processes in the nucleus - medium-sized ncRNAs, nuclear speckles and Rbfox1-mediated splicing HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins IGF2BP1 induces high-risk neuroblastoma in transgenic mice and enhances tumor progression in synergy with MYCN Investigation of Actin-MRTF-A protein complexes in fibroblasts Phänotypische und molekulare Charakterisierung neuer potenzieller Inhibitoren der ribosomalen Kinase RPS6KA2 Self-assembly of intrinsically disordered proteins into amyloid fibrils and liquid condensates Somatic functions of Bicaudal-C in C. elegans Structural characterization of the protein : protein interaction between the tumor suppressor p53 and S100β IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression Correction: Identification of lymphocyte cell-specific protein-tyrosine kinase (LCK) as a driver for invasion and migration of oral cancer by tumor heterogeneity exploitation Posttranskriptionelle Regulation desmosomaler mRNA durch RNA-bindende Proteine The dual role of the desmosomal regulator Plakophilin 3 in cellular adhesion and cell cycle progression Fast forward evolution in real time: the rapid spread of SARS-CoV-2 variant of concern lineage B.1.1.7 in Saxony-Anhalt over a period of 5 months From lost adhesion to tumor spreading : the upregulation of IGF2BP1 controls a targetable mesenchymal shift in ovarian cancer In-Vitro-Rekonstitution der Deadenylierung und Translationsrepression der nanos-mRNA aus D. melanogaster Serologische Längsschnittstudie von SARS-CoV-2 positiven Personen The oncofetal RNA-binding protein IGF2BP1 is a miRNA- and m6A-dependent enhancer of gene expression in cancer [Kumulative Dissertation] Identification of lymphocyte cell-specific protein-tyrosine kinase (LCK) as a driver for invasion and migration of oral cancer by tumor heterogeneity exploitation B cell receptor signaling and its role in pathology and therapy of Chronic Lymphocytic Leukemia [Kumulative Dissertation] Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning Developmentally regulated proteolysis of cytoplasmic polyA polymerase GLD-2 Influence of miR-221/222 on GIRK1/4 channel function and LTCC-dependent calcium handling in cardiomyocytes Posttranscriptional regulation of the components of the human leukocyte antigen class I antigen processing and presentation machinery as an immune escape mechanism in melanoma NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration KLF4 K409Q –mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment Analysis of the topology of the platform protein Gab1 and its interactions with the adaptor Grb2 Ex vivo and in vitro characterization of natural killer cell functions and receptor expression profiles in obesity Expression of UGT76E12 and UGT76E11 : two UDP-glycosyltransferases involved in biotic and abiotic stress responses, is differentially regulated by their antisense lncRNAs IGF2BP1 is the first positive marker for anaplastic thyroid carcinoma and an enhancer of a targetable gene expression signature In vitro und in vivo Untersuchungen zur Tumorigenität des Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) : [kumulative Dissertation] Molekulare Charakterisierung des Effekts von zielgerichteten Therapien in pankreatischen Neuroendokrinen Tumoren und Tumor-assoziierten Makrophagen in vitro und in vivo Unraveling the role of the RNA-binding protein MUSASHI1 in chemoresistance and malignancy of Glioblastoma WISP1-AS1, a long noncoding RNA, upregulated in human renal cells exposed to the mycotoxin ochratoxin A and in human renal cancer cells Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3 Morphologische und transkriptomische Analyse neuronaler Zellen basierend auf Verfahren der Bildverarbeitung und Sequenzanalyse Mud2 functions in transcription by recruiting the Prp19 and TREX complexes to transcribed genes RNA Sequencing of Collecting Duct Renal Cell Carcinoma Suggests an Interaction between miRNA and Target Genes and a Predominance of Deregulated Solute Carrier Genes The role of small nucleolar Ribonucleoprotein complexes in lung cancer Zusammensetzung von IGF2BP1-enthaltenden Ribonukleoproteinkomplexen Recognition of RNA N 6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA-binding proteins) is modulated by distinct RNA-binding domains Aspects of cell adhesion : the function of vinculin and vasodilator-stimulated phosphoprotein VASP in actin-membrane attachment ; kumulative Arbeit

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Katalog der Deutschen Nationalbibliothek

Stefan Hüttelmaier (1973-)

Development of new pyrazoles as class I HDAC inhibitors: Synthesis, molecular modeling, and biological characterization in leukemia cells

Utilization of an optimized AlphaFold protein model for structure‐based design of a selective HDAC11 inhibitor with anti‐neuroblastoma activity

Das RNA-bindende Protein RAVER1 moduliert die miR/RISC-Aktivität und TGFβ-abhängige EMT durch Regulation des alternativen Spleißens

Deciphering the role of LINC00261 and FOXA2 in epithelial-mesenchymal transition and metastasis of pancreatic cancer cells

From sequencing to function : a triad of RNA-guided processes in the nucleus - medium-sized ncRNAs, nuclear speckles and Rbfox1-mediated splicing

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins

IGF2BP1 induces high-risk neuroblastoma in transgenic mice and enhances tumor progression in synergy with MYCN

Investigation of Actin-MRTF-A protein complexes in fibroblasts

Phänotypische und molekulare Charakterisierung neuer potenzieller Inhibitoren der ribosomalen Kinase RPS6KA2

Self-assembly of intrinsically disordered proteins into amyloid fibrils and liquid condensates

Somatic functions of Bicaudal-C in C. elegans

Structural characterization of the protein : protein interaction between the tumor suppressor p53 and S100β

IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression

Correction: Identification of lymphocyte cell-specific protein-tyrosine kinase (LCK) as a driver for invasion and migration of oral cancer by tumor heterogeneity exploitation

Posttranskriptionelle Regulation desmosomaler mRNA durch RNA-bindende Proteine

The dual role of the desmosomal regulator Plakophilin 3 in cellular adhesion and cell cycle progression

Fast forward evolution in real time: the rapid spread of SARS-CoV-2 variant of concern lineage B.1.1.7 in Saxony-Anhalt over a period of 5 months

From lost adhesion to tumor spreading : the upregulation of IGF2BP1 controls a targetable mesenchymal shift in ovarian cancer

In-Vitro-Rekonstitution der Deadenylierung und Translationsrepression der nanos-mRNA aus D. melanogaster

Serologische Längsschnittstudie von SARS-CoV-2 positiven Personen

The oncofetal RNA-binding protein IGF2BP1 is a miRNA- and m6A-dependent enhancer of gene expression in cancer [Kumulative Dissertation]

Identification of lymphocyte cell-specific protein-tyrosine kinase (LCK) as a driver for invasion and migration of oral cancer by tumor heterogeneity exploitation

B cell receptor signaling and its role in pathology and therapy of Chronic Lymphocytic Leukemia [Kumulative Dissertation]

Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning

Developmentally regulated proteolysis of cytoplasmic polyA polymerase GLD-2

Influence of miR-221/222 on GIRK1/4 channel function and LTCC-dependent calcium handling in cardiomyocytes

Posttranscriptional regulation of the components of the human leukocyte antigen class I antigen processing and presentation machinery as an immune escape mechanism in melanoma

NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration

KLF4 K409Q –mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment

Analysis of the topology of the platform protein Gab1 and its interactions with the adaptor Grb2

Ex vivo and in vitro characterization of natural killer cell functions and receptor expression profiles in obesity

Expression of UGT76E12 and UGT76E11 : two UDP-glycosyltransferases involved in biotic and abiotic stress responses, is differentially regulated by their antisense lncRNAs

IGF2BP1 is the first positive marker for anaplastic thyroid carcinoma and an enhancer of a targetable gene expression signature

In vitro und in vivo Untersuchungen zur Tumorigenität des Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) : [kumulative Dissertation]

Molekulare Charakterisierung des Effekts von zielgerichteten Therapien in pankreatischen Neuroendokrinen Tumoren und Tumor-assoziierten Makrophagen in vitro und in vivo

Unraveling the role of the RNA-binding protein MUSASHI1 in chemoresistance and malignancy of Glioblastoma

WISP1-AS1, a long noncoding RNA, upregulated in human renal cells exposed to the mycotoxin ochratoxin A and in human renal cancer cells

Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3

Morphologische und transkriptomische Analyse neuronaler Zellen basierend auf Verfahren der Bildverarbeitung und Sequenzanalyse

Mud2 functions in transcription by recruiting the Prp19 and TREX complexes to transcribed genes

RNA Sequencing of Collecting Duct Renal Cell Carcinoma Suggests an Interaction between miRNA and Target Genes and a Predominance of Deregulated Solute Carrier Genes

The role of small nucleolar Ribonucleoprotein complexes in lung cancer

Zusammensetzung von IGF2BP1-enthaltenden Ribonukleoproteinkomplexen

Recognition of RNA N 6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA-binding proteins) is modulated by distinct RNA-binding domains

Aspects of cell adhesion : the function of vinculin and vasodilator-stimulated phosphoprotein VASP in actin-membrane attachment ; kumulative Arbeit