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Wolfram Klapper (1971-)

Pathologe

Name	Wolfram Klapper
Zeit	1971- (Lebensdaten)
Ort	Kiel (Wirkungsort) Deutschland
Akademischer Grad bzw. Titel	Dr. med.
Beruf	Pathologe (charakteristischer Beruf)
Beziehung	Universitätsklinikum Schleswig-Holstein. Campus Kiel
Weitere Angaben	Habil. am Inst. für Pathologie der Univ. Kiel; Institut für Pathologie Sektion Hämatopathologie
Datensatztyp	Person
GND-Nummer	123029880
Datensatz-ID	123029880
Beteiligt an alle anzeigen Lack of SMARCB1 expression characterizes a subset of human and murine peripheral T-cell lymphomas Identification, risk factors, and clinical course of CNS relapse in DLBCL patients across 19 prospective phase 2 and 3 trials—a LYSA and GLA/ DSHNHL collaboration The addition of bortezomib to rituximab, high-dose cytarabine and dexamethasone in relapsed or refractory mantle cell lymphoma—a randomized, open-label phase III trial of the European mantle cell lymphoma network Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial Histopathological growth patterns in patients with advanced nodular lymphocyte-predominant Hodgkin lymphoma treated within the randomized HD18 study: a report from the German Hodgkin Study Group Super-enhancer-based identification of a BATF3/IL-2R−module reveals vulnerabilities in anaplastic large cell lymphoma Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma Outcome prediction by interim positron emission tomography and IgM monoclonal gammopathy in diffuse large B-cell lymphoma Novel insights into the pathogenesis of follicular lymphoma by molecular profiling of localized and systemic disease forms The addition of rituximab to chemotherapy improves overall survival in mantle cell lymphoma—a pooled trials analysis The spectrum of nodular lymphocyte predominant Hodgkin lymphoma: a report of the lymphoma workshop of the 20th meeting of the European Association for Haematopathology Molecular profiling of EBV associated diffuse large B-cell lymphoma Clinical outcome of Mantle Cell Lymphoma patients with high-risk disease (high-risk MIPI-c or high p53 expression) Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age Cyclin D1 expression, cell proliferation, and clonal persistence characterize primary cutaneous CD4+ small or medium T-cell lymphoproliferative disorder Divergent effects of EZH1 and EZH2 protein expression on the prognosis of patients with T-cell lymphomas Frequency and prognostic implications of KMT2A rearrangements in children with precursor B-cell lymphoma Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A) Molekulare Charakterisierung adulter Burkitt Lymphome zur Identifizierung altersassoziierter genetischer Veränderungen Frequency and prognostic implications of KMT2A rearrangements in children with precursor B-cell lymphoma Lymphome und andere hämatologische Neoplasien im Hoden PARP14 is a novel target in STAT6 mutant follicular lymphoma Characterization of IG-MYC-breakpoints and their application for quantitative minimal disease monitoring in high-risk pediatric Burkitt-lymphoma and -leukemia The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms CD147 a direct target of miR-146a supports energy metabolism and promotes tumor growth in ALK+ ALCL Neues aus Pathologie und Pathophysiologie des Hodgkin-Lymphoms 9p24.1 alterations and programmed cell death 1 ligand 1 expression in early stage unfavourable classical Hodgkin lymphoma: an analysis from the German Hodgkin Study Group NIVAHL trial Antibody-negative paraneoplastic autoimmune multiorgan syndrome (PAMS) in a patient with follicular lymphoma accompanied by an excess of peripheral blood CD8+ lymphocytes Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age LINC00892 is an lncRNA induced by T cell activation and expressed by follicular lymphoma-resident T helper cells LINC00892 Is an lncRNA Induced by T Cell Activation and Expressed by Follicular Lymphoma-Resident T Helper Cells Molecular characteristics of diffuse large B-cell lymphoma in the Positron Emission Tomography-Guided Therapy of Aggressive Non-Hodgkin lymphomas (PETAL) trial: correlation with interim PET and outcome Impact of germline polymorphisms in genes regulating glucose uptake on positron emission tomography findings and outcome in diffuse large B-cell lymphoma: results from the PETAL trial Reduction of immunosuppression combined with whole-brain radiotherapy and concurrent systemic rituximab is an effective yet toxic treatment of primary central nervous system post-transplant lymphoproliferative disorder (pCNS-PTLD): 14 cases from the prospective German PTLD registry The “Burkitt-like” immunophenotype and genotype is rarely encountered in diffuse large B cell lymphoma and high-grade B cell lymphoma, NOS Mantle cell lymphomas with concomitant MYC and CCND1 breakpoints are recurrently TdT positive and frequently show high-grade pathological and genetic features Adoptive Cell Transfer of Allogeneic Epstein-Barr Virus-Specific T Lymphocytes for Treatment of Refractory EBV-Associated Posttransplant Smooth Muscle Tumors : A Case Report Das Mikroenvironment des Follikulären Lymphoms zum Zeitpunkt der Primärdiagnose und des Rezidivs Digitale Pathologie und T-Zell-Rezeptor-Repertoire in sequentiellen Biopsien des klassischen Hodgkin Lymphoms Digitalisierte Bildanalysen des Tumormikromilieus von klassischen Hodgkin-Lymphomen : Quantifizierung der zellulären Zusammensetzung und Analyse der klinischen Relevanz Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP Genexpressionsanalyse der Zusammensetzung des Microenvironments im klassischen Hodgkin- Lymphom bei Erstdiagnose und im Rezidiv Histopathological growth patterns in patients with advanced nodular lymphocyte-predominant Hodgkin lymphoma treated within the randomized HD18 study: a report from the German Hodgkin Study Group Molecular features of non-anaplastic peripheral T-cell lymphoma in children and adolescents Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas Double-hit lymphoma of the male breast: a case report Reproducibility of histologic prognostic parameters for mantle cell lymphoma: cytology, Ki67, p53 and SOX11 1q und 12p als prognostische Marker kindlicher Keimzelltumoren Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of "MYC-negative" Burkitt lymphoma Double-hit lymphoma of the male breast: a case report Experience with provisional WHO‐entities large B‐cell lymphoma with IRF4‐rearrangement and Burkitt‐like lymphoma with 11q aberration in paediatric patients of the NHL‐BFM group Identification of the atypically modified autoantigen Ars2 as the target of B-cell receptors from activated B cell–type diffuse large B-cell lymphoma Second malignancies after treatment of childhood non-Hodgkin lymphoma: a report of the Berlin-Frankfurt-Muenster study group USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma Therapy of nodal Follicular Lymphoma (WHO grade 1/2) in clinical stage I/II using response adapted Involved Site Radiotherapy in combination with Obinutuzumab (Gazyvaro) - GAZAI Trial (GAZyvaro and response adapted Involved-site Radiotherapy): a study protocol for a single-arm, non-randomized, open, national, multi-center phase II trial Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach A modular transcriptome map of mature B cell lymphomas Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma

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Wolfram Klapper (1971-)

Lack of SMARCB1 expression characterizes a subset of human and murine peripheral T-cell lymphomas

Identification, risk factors, and clinical course of CNS relapse in DLBCL patients across 19 prospective phase 2 and 3 trials—a LYSA and GLA/ DSHNHL collaboration

The addition of bortezomib to rituximab, high-dose cytarabine and dexamethasone in relapsed or refractory mantle cell lymphoma—a randomized, open-label phase III trial of the European mantle cell lymphoma network

Assessing the efficacy and tolerability of PET-guided BrECADD versus eBEACOPP in advanced-stage, classical Hodgkin lymphoma (HD21): a randomised, multicentre, parallel, open-label, phase 3 trial

Histopathological growth patterns in patients with advanced nodular lymphocyte-predominant Hodgkin lymphoma treated within the randomized HD18 study: a report from the German Hodgkin Study Group

Super-enhancer-based identification of a BATF3/IL-2R−module reveals vulnerabilities in anaplastic large cell lymphoma

Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma

Outcome prediction by interim positron emission tomography and IgM monoclonal gammopathy in diffuse large B-cell lymphoma

Novel insights into the pathogenesis of follicular lymphoma by molecular profiling of localized and systemic disease forms

The addition of rituximab to chemotherapy improves overall survival in mantle cell lymphoma—a pooled trials analysis

The spectrum of nodular lymphocyte predominant Hodgkin lymphoma: a report of the lymphoma workshop of the 20th meeting of the European Association for Haematopathology

Molecular profiling of EBV associated diffuse large B-cell lymphoma

Clinical outcome of Mantle Cell Lymphoma patients with high-risk disease (high-risk MIPI-c or high p53 expression)

Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age

Cyclin D1 expression, cell proliferation, and clonal persistence characterize primary cutaneous CD4+ small or medium T-cell lymphoproliferative disorder

Divergent effects of EZH1 and EZH2 protein expression on the prognosis of patients with T-cell lymphomas

Frequency and prognostic implications of KMT2A rearrangements in children with precursor B-cell lymphoma

Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A)

Molekulare Charakterisierung adulter Burkitt Lymphome zur Identifizierung altersassoziierter genetischer Veränderungen

Frequency and prognostic implications of KMT2A rearrangements in children with precursor B-cell lymphoma

Lymphome und andere hämatologische Neoplasien im Hoden

PARP14 is a novel target in STAT6 mutant follicular lymphoma

Characterization of IG-MYC-breakpoints and their application for quantitative minimal disease monitoring in high-risk pediatric Burkitt-lymphoma and -leukemia

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms

CD147 a direct target of miR-146a supports energy metabolism and promotes tumor growth in ALK+ ALCL

Neues aus Pathologie und Pathophysiologie des Hodgkin-Lymphoms

9p24.1 alterations and programmed cell death 1 ligand 1 expression in early stage unfavourable classical Hodgkin lymphoma: an analysis from the German Hodgkin Study Group NIVAHL trial

Antibody-negative paraneoplastic autoimmune multiorgan syndrome (PAMS) in a patient with follicular lymphoma accompanied by an excess of peripheral blood CD8+ lymphocytes

Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age

Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age

LINC00892 is an lncRNA induced by T cell activation and expressed by follicular lymphoma-resident T helper cells

LINC00892 Is an lncRNA Induced by T Cell Activation and Expressed by Follicular Lymphoma-Resident T Helper Cells

Molecular characteristics of diffuse large B-cell lymphoma in the Positron Emission Tomography-Guided Therapy of Aggressive Non-Hodgkin lymphomas (PETAL) trial: correlation with interim PET and outcome

Impact of germline polymorphisms in genes regulating glucose uptake on positron emission tomography findings and outcome in diffuse large B-cell lymphoma: results from the PETAL trial

Reduction of immunosuppression combined with whole-brain radiotherapy and concurrent systemic rituximab is an effective yet toxic treatment of primary central nervous system post-transplant lymphoproliferative disorder (pCNS-PTLD): 14 cases from the prospective German PTLD registry

The “Burkitt-like” immunophenotype and genotype is rarely encountered in diffuse large B cell lymphoma and high-grade B cell lymphoma, NOS

Mantle cell lymphomas with concomitant MYC and CCND1 breakpoints are recurrently TdT positive and frequently show high-grade pathological and genetic features

Adoptive Cell Transfer of Allogeneic Epstein-Barr Virus-Specific T Lymphocytes for Treatment of Refractory EBV-Associated Posttransplant Smooth Muscle Tumors : A Case Report

Das Mikroenvironment des Follikulären Lymphoms zum Zeitpunkt der Primärdiagnose und des Rezidivs

Digitale Pathologie und T-Zell-Rezeptor-Repertoire in sequentiellen Biopsien des klassischen Hodgkin Lymphoms

Digitalisierte Bildanalysen des Tumormikromilieus von klassischen Hodgkin-Lymphomen : Quantifizierung der zellulären Zusammensetzung und Analyse der klinischen Relevanz

Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP

Gene expression-based outcome prediction in advanced stage classical Hodgkin lymphoma treated with BEACOPP

Genexpressionsanalyse der Zusammensetzung des Microenvironments im klassischen Hodgkin- Lymphom bei Erstdiagnose und im Rezidiv

Histopathological growth patterns in patients with advanced nodular lymphocyte-predominant Hodgkin lymphoma treated within the randomized HD18 study: a report from the German Hodgkin Study Group

Molecular features of non-anaplastic peripheral T-cell lymphoma in children and adolescents

Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas

Double-hit lymphoma of the male breast: a case report

Reproducibility of histologic prognostic parameters for mantle cell lymphoma: cytology, Ki67, p53 and SOX11

1q und 12p als prognostische Marker kindlicher Keimzelltumoren

Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of "MYC-negative" Burkitt lymphoma

Double-hit lymphoma of the male breast: a case report

Experience with provisional WHO‐entities large B‐cell lymphoma with IRF4‐rearrangement and Burkitt‐like lymphoma with 11q aberration in paediatric patients of the NHL‐BFM group

Identification of the atypically modified autoantigen Ars2 as the target of B-cell receptors from activated B cell–type diffuse large B-cell lymphoma

Second malignancies after treatment of childhood non-Hodgkin lymphoma: a report of the Berlin-Frankfurt-Muenster study group

USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma

Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach

A modular transcriptome map of mature B cell lymphomas

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma