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Simone Niclou

Biologin

Name	Simone Niclou
Zeit	1994- (Wirkungsdaten)
Ort	Luxemburg Norwegen
Geschlecht	weiblich
Akademischer Grad bzw. Titel	Prof. Dr.
Beruf	Biologin (charakteristischer Beruf) Hochschullehrerin
Variante	Simone P. Niclou
Beziehung	Université du Luxembourg Universitetet i Bergen
Quelle	https://www.uni.lu/fstm-en/people/simone-p-niclou/ (Stand: 28.11.2024)
Datensatztyp	Person
GND-Nummer	1275965202
Datensatz-ID	1275965202
Beteiligt an alle anzeigen Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts Magnetic resonance imaging-guided intracranial resection of glioblastoma tumors in patient-derived orthotopic xenografts leads to clinically relevant tumor recurrence Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas Increased formate overflow is a hallmark of oxidative cancer Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures EGFL7 enhances surface expression of integrin α 5 β 1 to promote angiogenesis in malignant brain tumors EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures Altered metabolic landscape in IDH ‐mutant gliomas affects phospholipid, energy, and oxidative stress pathways Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors The Thrombin Receptor in the Nervous System

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Simone Niclou

Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

Magnetic resonance imaging-guided intracranial resection of glioblastoma tumors in patient-derived orthotopic xenografts leads to clinically relevant tumor recurrence

Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas

Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment

Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas

Increased formate overflow is a hallmark of oxidative cancer

Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures

EGFL7 enhances surface expression of integrin α 5 β 1 to promote angiogenesis in malignant brain tumors

EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors

Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma

Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures

Altered metabolic landscape in IDH ‐mutant gliomas affects phospholipid, energy, and oxidative stress pathways

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG

Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas

Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG

Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system

Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

The Thrombin Receptor in the Nervous System