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Jörn Dengjel (1975-)

Biochemiker

Name	Jörn Dengjel
Zeit	1975- (Lebensdaten)
Ort	Freiburg im Üechtland (2016-) (Wirkungsort) Deutschland
Akademischer Grad bzw. Titel	Prof. Dr.
Beruf	Biochemiker (charakteristischer Beruf)
Beziehung	Klinik für Dermatologie und Venerologie (01.12.2013-2016)
Weitere Angaben	Diss., 2005, Universität Tübingen, Fakultät für Chemie und Pharmazie
Datensatztyp	Person
GND-Nummer	129922048
Datensatz-ID	129922048
Beteiligt an alle anzeigen The mTOR pathway controls phosphorylation of BRAF at T401 Spermidine is essential for fasting-mediated autophagy and longevity A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease Dipeptidyl peptidase-4-mediated fibronectin processing evokes a pro-fibrotic extracellular matrix Histone deacetylase inhibition mitigates fibrosis-driven disease progression in recessive dystrophic epidermolysis bullosa ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease The mTOR pathway controls phosphorylation of BRAF at T401 Ultrafast and Controlled Capturing, Loading, and Release of Extracellular Vesicles by a Portable Microstructured Electrochemical Fluidic Device Ultrafast and Controlled Capturing, Loading, and Release of Extracellular Vesicles by a Portable Microstructured Electrochemical Fluidic Device (Adv. Mater. 44/2023) Analyses of fibroblasts associated with chronic wounds suggest a major role in chronic wound pathophysiology Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy mTORC1 controls Golgi architecture and vesicle secretion by phosphorylation of SCYL1 The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity mTORC1 controls Golgi architecture and vesicle secretion by phosphorylation of SCYL1 Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity The lectin LecB induces patches with basolateral characteristics at the apical membrane to promote pseudomonas aeruginosa host cell invasion Bacterial lectin BambL acts as a B cell superantigen Pro‐inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang‐(1‐7) Bacterial lectin BambL acts as a B cell superantigen EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery Increased abundance of Cbl E3 ligases alters PDGFR signaling in recessive dystrophic epidermolysis bullosa Pro‐inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang‐(1‐7) Proteasomal degradation induced by DPP9‐mediated processing competes with mitochondrial protein import Nephronophthisis gene products display RNA-binding properties and are recruited to stress granules Proteomic profiling of fibroblasts isolated from chronic wounds identifies disease-relevant signaling pathways The Pseudomonas aeruginosa lectin LecB causes integrin internalization and inhibits epithelial wound healing Annexin A7 is required for ESCRT III-mediated plasma membrane repair Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species Annexin A7 is required for ESCRT III-mediated plasma membrane repair Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: Lessons for therapies in keratin disorders HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα Cilia‐localized LKB 1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney Control of RAB 7 activity and localization through the retromer‐TBC1D5 complex enables RAB 7‐dependent mitophagy Beyond Global Charge: Role of Amine Bulkiness and Protein Fingerprint on Nanoparticle–Cell Interaction Protein Coronas: Beyond Global Charge: Role of Amine Bulkiness and Protein Fingerprint on Nanoparticle–Cell Interaction (Small 46/2018) A multi-layered quantitative in vivo expression atlas of the podocyte unravels Kidney disease candidate genes ARP3 controls the podocyte architecture at the kidney filtration barrier Cilia‐localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney Combinatorial omics analysis reveals perturbed lysosomal homeostasis in collagen VII-deficient keratinocytes HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα Influenza a virus induces autophagosomal targeting of ribosomal proteins Role of influenza A virus NP acetylation on viral growth and replication Insights into autosomal dominant polycystic kidney disease by quantitative mass spectrometry-based proteomics Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition Dietary spermidine for lowering high blood pressure Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A Respiratory status determines the effect of emodin on cell viability Role of influenza A virus NP acetylation on viral growth and replication The atypical kinase RIOK1 promotes tumor growth and invasive behavior Axitinib and sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells The deubiquitinase Usp27x stabilizes the BH 3‐only protein Bim and enhances apoptosis Axitinib and Sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells

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Katalog der Deutschen Nationalbibliothek

Jörn Dengjel (1975-)

The mTOR pathway controls phosphorylation of BRAF at T401

Spermidine is essential for fasting-mediated autophagy and longevity

A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease

Dipeptidyl peptidase-4-mediated fibronectin processing evokes a pro-fibrotic extracellular matrix

Histone deacetylase inhibition mitigates fibrosis-driven disease progression in recessive dystrophic epidermolysis bullosa

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease

The mTOR pathway controls phosphorylation of BRAF at T401

Ultrafast and Controlled Capturing, Loading, and Release of Extracellular Vesicles by a Portable Microstructured Electrochemical Fluidic Device

Ultrafast and Controlled Capturing, Loading, and Release of Extracellular Vesicles by a Portable Microstructured Electrochemical Fluidic Device (Adv. Mater. 44/2023)

Analyses of fibroblasts associated with chronic wounds suggest a major role in chronic wound pathophysiology

Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation

Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy

mTORC1 controls Golgi architecture and vesicle secretion by phosphorylation of SCYL1

The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity

mTORC1 controls Golgi architecture and vesicle secretion by phosphorylation of SCYL1

Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants

The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity

The lectin LecB induces patches with basolateral characteristics at the apical membrane to promote pseudomonas aeruginosa host cell invasion

Bacterial lectin BambL acts as a B cell superantigen

Pro‐inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang‐(1‐7)

Bacterial lectin BambL acts as a B cell superantigen

EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission

Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery

Increased abundance of Cbl E3 ligases alters PDGFR signaling in recessive dystrophic epidermolysis bullosa

Pro‐inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang‐(1‐7)

Proteasomal degradation induced by DPP9‐mediated processing competes with mitochondrial protein import

Nephronophthisis gene products display RNA-binding properties and are recruited to stress granules

Proteomic profiling of fibroblasts isolated from chronic wounds identifies disease-relevant signaling pathways

The Pseudomonas aeruginosa lectin LecB causes integrin internalization and inhibits epithelial wound healing

Annexin A7 is required for ESCRT III-mediated plasma membrane repair

Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species

Annexin A7 is required for ESCRT III-mediated plasma membrane repair

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles

Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: Lessons for therapies in keratin disorders

HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα

Cilia‐localized LKB 1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney

Control of RAB 7 activity and localization through the retromer‐TBC1D5 complex enables RAB 7‐dependent mitophagy

Beyond Global Charge: Role of Amine Bulkiness and Protein Fingerprint on Nanoparticle–Cell Interaction

Protein Coronas: Beyond Global Charge: Role of Amine Bulkiness and Protein Fingerprint on Nanoparticle–Cell Interaction (Small 46/2018)

A multi-layered quantitative in vivo expression atlas of the podocyte unravels Kidney disease candidate genes

ARP3 controls the podocyte architecture at the kidney filtration barrier

Cilia‐localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney

Combinatorial omics analysis reveals perturbed lysosomal homeostasis in collagen VII-deficient keratinocytes

HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα

Influenza a virus induces autophagosomal targeting of ribosomal proteins

Role of influenza A virus NP acetylation on viral growth and replication

Insights into autosomal dominant polycystic kidney disease by quantitative mass spectrometry-based proteomics

Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition

Dietary spermidine for lowering high blood pressure

Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A

Respiratory status determines the effect of emodin on cell viability

Role of influenza A virus NP acetylation on viral growth and replication

The atypical kinase RIOK1 promotes tumor growth and invasive behavior

Axitinib and sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells

The deubiquitinase Usp27x stabilizes the BH 3‐only protein Bim and enhances apoptosis

Axitinib and Sorafenib are potent in tyrosine kinase inhibitor resistant chronic myeloid leukemia cells