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Melanie Börries (1971-)

Name	Melanie Börries
Zeit	1971- (Lebensdaten)
Ort	Deutschland
Geschlecht	weiblich
Akademischer Grad bzw. Titel	Dr. med. Dr. phil
Variante	Melanie Boerries
Beziehung	Albert-Ludwigs-Universität Freiburg. Institut für Molekulare Medizin und Zellforschung Tumorzentrum Freiburg - CCCF Medizin (Studienfach) Cytologie (Thema) Kardiologie (Thema)
Weitere Angaben	Diss. Medizinische Fakultät
Datensatztyp	Person
GND-Nummer	129955493
Datensatz-ID	129955493
Beteiligt an alle anzeigen Empowering personalized oncology: evolution of digital support and visualization tools for molecular tumor boards Spatial single-cell profiling and neighbourhood analysis reveal the determinants of immune architecture connected to checkpoint inhibitor therapy outcome in hepatocellular carcinoma ZBTB18 regulates cytokine expression and affects microglia/macrophage recruitment and commitment in glioblastoma Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease Primary Results of Patients with Genitourinary Malignancies Presented at a Molecular Tumor Board Alterations in the microenvironment of junctional epidermolysis bullosa keratinocytes: a gene expression study Author Correction: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification BH3 mimetics and azacitidine show synergistic effects on juvenile myelomonocytic leukemia Biallelic inactivation of the NF1 tumour suppressor gene in juvenile myelomonocytic leukaemia: genetic evidence of driver function and implications for diagnostic workup Combination of Lenvatinib and Pembrolizumab Is an Effective Treatment Option for Anaplastic and Poorly Differentiated Thyroid Carcinoma Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors Correction: Antón-García et al. TGFβ1-Induced EMT in the MCF10A Mammary Epithelial Cell Line Model Is Executed Independently of SNAIL1 and ZEB1 but Relies on JUNB-Coordinated Transcriptional Regulation. Cancers 2023, 15, 588 Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity Das Verbundprojekt "Personalisierte Medizin für die Onkologie" (PM4Onco) als Teil der Medizininformatik-Initiative (MII) = The collaborative project "Personalized medicine for oncology" (PM4Onco) as part of the Medical Informatics Initiative (MII) Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1 Gene editing of hematopoietic stem cells restores T cell response in familial hemophagocytic lymphohistiocytosis Identification of low molecular weight peptides targeting EpCAM and CD44v6 Integrated analysis of cell-free DNA and novel protein biomarkers for stratification and therapy monitoring in stage IV pancreatic cancer: a preliminary study Leveraging chromatin state transitions for the identification of regulatory networks orchestrating heart regeneration LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL Modulation of TCR stimulation and pifithrin-α improves the genomic safety profile of CRISPR-engineered human T cells On- and off-target effects of paired CRISPR-Cas nickase in primary human cells PM4Onco: personalisierte Medizin für die Onkologie : : effektive Datennutzung für molekulare Tumorboards = PM4Onco: personalized medicine for oncology : effective use of data for molecular tumor boards ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease Safe and effective liver-directed AAV-mediated homology-independent targeted integration in mouse models of inherited diseases Sondersituation der Daten in der Onkologie = Data complexity in oncology The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection The German Medical Informatics Initiative Broad Consent in the emergency department: a single centre prospective observational study to assess consenting mode dependent success rates ZBTB18 regulates cytokine expression and affects microglia/macrophage recruitment and commitment in glioblastoma BH3 mimetics and azacitidine show synergistic effects on juvenile myelomonocytic leukemia Harnessing CD3 diversity to optimize CAR T cells Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification Spatially resolved transcriptomic profiles reveal unique defining molecular features of infiltrative 5ALA-metabolizing cells associated with glioblastoma recurrence Non-canonical functions of SNAIL drive context-specific cancer progression BRAF Δβ3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability = BRAF [delta][beta]3-[alpha]C in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability Breast Cancer Stem Cell-Derived Tumors Escape from γδ T-cell Immunosurveillance In Vivo by Modulating γδ T-cell Ligands Breast cancer stem cell–derived tumors escape from [gamma][delta] T-cell immunosurveillance in vivo by modulating [gamma][delta] T-cell ligands Cell-based models of "cytokine release syndrome" endorse CD40L and granulocyte–macrophage colony-stimulating factor knockout in chimeric antigen receptor T cells as mitigation strategy Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of [beta]-hemoglobinopathies Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4+ T cells Extending cBioPortal for therapy recommendation documentation in molecular tumor boards: development and usability study Harnessing CD3 diversity to optimize CAR T cells Identification of the needs and preferences of patients with cancer for the development of a clinic app : : qualitative study Immune surveillance of acute myeloid leukemia is mediated by HLA-presented antigens on leukemia progenitor cells Impact of signaling pathways and the extracellular matrix in cancer development In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts Interferon-driven immune dysregulation in common variable immunodeficiency-associated villous atrophy and norovirus infection Microglia modulate TNF[alpha]‐mediated synaptic plasticity MIRACUM-Pipe : : an adaptable pipeline for next-generation <br>sequencing analysis, reporting, and visualization for clinical decision making Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients Non-canonical functions of SNAIL drive context-specific cancer progression Non-invasive monitoring of neoadjuvant radiation therapy response in soft tissue sarcomas by multiparametric MRI and quantification of circulating tumor DNA — a study protocol

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Melanie Börries (1971-)

Empowering personalized oncology: evolution of digital support and visualization tools for molecular tumor boards

Spatial single-cell profiling and neighbourhood analysis reveal the determinants of immune architecture connected to checkpoint inhibitor therapy outcome in hepatocellular carcinoma

ZBTB18 regulates cytokine expression and affects microglia/macrophage recruitment and commitment in glioblastoma

Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors

The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection

Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level

Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome

LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease

Primary Results of Patients with Genitourinary Malignancies Presented at a Molecular Tumor Board

Alterations in the microenvironment of junctional epidermolysis bullosa keratinocytes: a gene expression study

Author Correction: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification

BH3 mimetics and azacitidine show synergistic effects on juvenile myelomonocytic leukemia

Biallelic inactivation of the NF1 tumour suppressor gene in juvenile myelomonocytic leukaemia: genetic evidence of driver function and implications for diagnostic workup

Combination of Lenvatinib and Pembrolizumab Is an Effective Treatment Option for Anaplastic and Poorly Differentiated Thyroid Carcinoma

Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors

Correction: Antón-García et al. TGFβ1-Induced EMT in the MCF10A Mammary Epithelial Cell Line Model Is Executed Independently of SNAIL1 and ZEB1 but Relies on JUNB-Coordinated Transcriptional Regulation. Cancers 2023, 15, 588

Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity

Das Verbundprojekt "Personalisierte Medizin für die Onkologie" (PM4Onco) als Teil der Medizininformatik-Initiative (MII) = The collaborative project "Personalized medicine for oncology" (PM4Onco) as part of the Medical Informatics Initiative (MII)

Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level

Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1

Gene editing of hematopoietic stem cells restores T cell response in familial hemophagocytic lymphohistiocytosis

Identification of low molecular weight peptides targeting EpCAM and CD44v6

Integrated analysis of cell-free DNA and novel protein biomarkers for stratification and therapy monitoring in stage IV pancreatic cancer: a preliminary study

Leveraging chromatin state transitions for the identification of regulatory networks orchestrating heart regeneration

LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL

Modulation of TCR stimulation and pifithrin-α improves the genomic safety profile of CRISPR-engineered human T cells

On- and off-target effects of paired CRISPR-Cas nickase in primary human cells

PM4Onco: personalisierte Medizin für die Onkologie : : effektive Datennutzung für molekulare Tumorboards = PM4Onco: personalized medicine for oncology : effective use of data for molecular tumor boards

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease

Safe and effective liver-directed AAV-mediated homology-independent targeted integration in mouse models of inherited diseases

Sondersituation der Daten in der Onkologie = Data complexity in oncology

The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection

The German Medical Informatics Initiative Broad Consent in the emergency department: a single centre prospective observational study to assess consenting mode dependent success rates

ZBTB18 regulates cytokine expression and affects microglia/macrophage recruitment and commitment in glioblastoma

BH3 mimetics and azacitidine show synergistic effects on juvenile myelomonocytic leukemia

Harnessing CD3 diversity to optimize CAR T cells

Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients

Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification

Spatially resolved transcriptomic profiles reveal unique defining molecular features of infiltrative 5ALA-metabolizing cells associated with glioblastoma recurrence

Non-canonical functions of SNAIL drive context-specific cancer progression

BRAF Δβ3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability = BRAF [delta][beta]3-[alpha]C in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability

Breast Cancer Stem Cell-Derived Tumors Escape from γδ T-cell Immunosurveillance In Vivo by Modulating γδ T-cell Ligands

Breast cancer stem cell–derived tumors escape from [gamma][delta] T-cell immunosurveillance in vivo by modulating [gamma][delta] T-cell ligands

Cell-based models of "cytokine release syndrome" endorse CD40L and granulocyte–macrophage colony-stimulating factor knockout in chimeric antigen receptor T cells as mitigation strategy

Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of [beta]-hemoglobinopathies

Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4+ T cells

Extending cBioPortal for therapy recommendation documentation in molecular tumor boards: development and usability study

Harnessing CD3 diversity to optimize CAR T cells

Identification of the needs and preferences of patients with cancer for the development of a clinic app : : qualitative study

Immune surveillance of acute myeloid leukemia is mediated by HLA-presented antigens on leukemia progenitor cells

Impact of signaling pathways and the extracellular matrix in cancer development

In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts

In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts

Interferon-driven immune dysregulation in common variable immunodeficiency-associated villous atrophy and norovirus infection

Microglia modulate TNF[alpha]‐mediated synaptic plasticity

MIRACUM-Pipe : : an adaptable pipeline for next-generation <br>sequencing analysis, reporting, and visualization for clinical decision making

Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients

Non-canonical functions of SNAIL drive context-specific cancer progression

Non-invasive monitoring of neoadjuvant radiation therapy response in soft tissue sarcomas by multiparametric MRI and quantification of circulating tumor DNA — a study protocol