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Georg Häcker (1964-)

Arzt

Name	Georg Häcker
Zeit	1964- (Lebensdaten)
Ort	Esslingen am Neckar (Geburtsort) Deutschland
Geschlecht	männlich
Akademischer Grad bzw. Titel	Prof. Dr.
Beruf	Arzt (charakteristischer Beruf)
Variante	Georg A. Häcker G. Häcker
Beziehung	Institut für Medizinische Mikrobiologie und Hygiene (Freiburg im Breisgau)
Weitere Angaben	Dissertation 1991; Habilitation 1998; Fachgebiet Medizinische Mikrobiologie, Immunologie und Hygiene
Datensatztyp	Person
GND-Nummer	131633481
Datensatz-ID	131633481
Beteiligt an alle anzeigen Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation Gram-negative bloodstream infections in six German university hospitals, 2016–2020: clinical and microbiological features Contribution of A1 to macrophage survival in cooperation with MCL-1 and BCL-XL in a murine cell model of myeloid differentiation The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection Epidemiological trends and susceptibility patterns of bloodstream infections caused by Enterococcus spp. in six German university hospitals: a prospectively evaluated multicentre cohort study from 2016 to 2020 of the R-Net study group ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease Charakterisierung des immunologischen Tumor-Mikromilieus kutaner Plattenepithelkarzinome in Patientengruppen unterschiedlicher Immunitätslage Chlamydia in pigs: intriguing bacteria associated with sub-clinical carriage and clinical disease, and with zoonotic potential Comparison of the diversity of anaerobic-cultured gut bacterial communities on different culture media using 16S rDNA sequencing Contribution of A1 to macrophage survival in cooperation with MCL-1 and BCL-XL in a murine cell model of myeloid differentiation Enhancing ascitic fungal infection diagnosis through next-generation sequencing: a pilot study in surgical ICU patients Epidemiological trends and susceptibility patterns of bloodstream infections caused by Enterococcus spp. in six German university hospitals: a prospectively evaluated multicentre cohort study from 2016 to 2020 of the R-Net study group Longitudinal dynamics of gut bacteriome and mycobiome interactions pre- and post-visceral surgery in Crohn’s disease Occurrence and trends of Clostridioides difficile infections in hospitalized patients: a prospective multicentre cohort study in six German university hospitals, 2016-2020 ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection The caspase-activated DNase promotes cellular senescence The role of the Caspase-Activated DNAse in growth behavior and tumor cell metastasis Weitere Primärmalignome beim kutanen malignen Melanom Etablierung der Genomischen Erreger-Surveillance zur Stärkung des Pandemie- und Infektionsschutzes in Deutschland An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective Corrigendum: Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency? Etablierung der Genomischen Erreger-Surveillance zur Stärkung des Pandemie- und Infektionsschutzes in Deutschland = Establishment of genomic pathogen surveillance to strengthen pandemic preparedness and infection prevention in Germany Next-Generation Sequencing compared to standard microbiological diagnostics in ascitic fluid bacterial infections of ICU patients – establishment of a 16S rRNA NGS platform in low-biomass samples Resolving colistin resistance and heteroresistance in Enterobacter species SPATA2 regulates inflammation and cell death independently of CYLD Sub-lethal signals in the mitochondrial apoptosis apparatus: pernicious by-product or physiological event? Sub-lethal signals in the mitochondrial apoptosis apparatus: pernicious by-product or physiological event? Mitochondria: intracellular sentinels of infections GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation Correction to: Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection Chlamydia trachomatis inhibits apoptosis in infected cells by targeting the pro-apoptotic proteins Bax and Bak The deubiquitinase Usp27x as a novel regulator of cFLIPL protein expression and sensitizer to death-receptor-induced apoptosis Chlamydia trachomatis inhibits apoptosis in infected cells by targeting the pro-apoptotic proteins Bax and Bak Correction to: Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency? GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse Surveillance and genomic analysis of third-generation cephalosporin-resistant and carbapenem-resistant klebsiella pneumoniae complex in Germany The Coxiella burnetii T4SS effector protein AnkG hijacks the 7SK small nuclear ribonucleoprotein complex for reprogramming host cell transcription The Coxiella burnetii T4SS effector protein AnkG hijacks the 7SK small nuclear ribonucleoprotein complex for reprogramming host cell transcription The deubiquitinase Usp27x as a novel regulator of cFLIPL protein expression and sensitizer to death-receptor-induced apoptosis Comprehensive integration of genome-wide association and gene expression studies reveals novel gene signatures and potential therapeutic targets for helicobacter pylori-induced gastric disease Diversity of cell death signaling pathways in macrophages upon infection with modified vaccinia virus Ankara (MVA) Host blood gene signatures can detect the progression to severe and cerebral malaria Importance of Bcl-2-family proteins in murine hematopoietic progenitor and early B cells Next- and third-generation sequencing outperforms culture-based methods in the diagnosis of ascitic fluid bacterial infections of ICU patients Sub-lethal activation of the caspase-activated DNAse contributes to genomic instability and tumorigenesis during infection and inflammation The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression Antimicrobial susceptibility patterns and wild-type MIC distributions of anaerobic bacteria at a German university hospital: a five-year retrospective study (2015–2019) Die Rolle von ausgewählten BH3-only Proteinen in der Lymphozytenentwicklung Klinische Risikostratifizierung von Clostridioides difficile-Infektionen mittels PCR-basierter Nachweisverfahren Point-of-care testing system for digital single cell detection of MRSA directly from nasal swabs Protocol for a prospective cohort study: Prevention of Transmissions by Effective Colonisation Tracking in Neonates (PROTECT-Neo) The innate lymphoid cell immune response in the mouse female genital tract upon infection with Chlamydia muridarum Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim A non‐death function of the mitochondrial apoptosis apparatus in immunity Checkpoint kinase 1 is essential for fetal and adult hematopoiesis

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Katalog der Deutschen Nationalbibliothek

Georg Häcker (1964-)

Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation

Gram-negative bloodstream infections in six German university hospitals, 2016–2020: clinical and microbiological features

Contribution of A1 to macrophage survival in cooperation with MCL-1 and BCL-XL in a murine cell model of myeloid differentiation

The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection

Epidemiological trends and susceptibility patterns of bloodstream infections caused by Enterococcus spp. in six German university hospitals: a prospectively evaluated multicentre cohort study from 2016 to 2020 of the R-Net study group

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease

Charakterisierung des immunologischen Tumor-Mikromilieus kutaner Plattenepithelkarzinome in Patientengruppen unterschiedlicher Immunitätslage

Chlamydia in pigs: intriguing bacteria associated with sub-clinical carriage and clinical disease, and with zoonotic potential

Comparison of the diversity of anaerobic-cultured gut bacterial communities on different culture media using 16S rDNA sequencing

Contribution of A1 to macrophage survival in cooperation with MCL-1 and BCL-XL in a murine cell model of myeloid differentiation

Enhancing ascitic fungal infection diagnosis through next-generation sequencing: a pilot study in surgical ICU patients

Epidemiological trends and susceptibility patterns of bloodstream infections caused by Enterococcus spp. in six German university hospitals: a prospectively evaluated multicentre cohort study from 2016 to 2020 of the R-Net study group

Longitudinal dynamics of gut bacteriome and mycobiome interactions pre- and post-visceral surgery in Crohn’s disease

Occurrence and trends of Clostridioides difficile infections in hospitalized patients: a prospective multicentre cohort study in six German university hospitals, 2016-2020

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease

The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection

The caspase-activated DNase promotes cellular senescence

The role of the Caspase-Activated DNAse in growth behavior and tumor cell metastasis

Weitere Primärmalignome beim kutanen malignen Melanom

Etablierung der Genomischen Erreger-Surveillance zur Stärkung des Pandemie- und Infektionsschutzes in Deutschland

An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective

Corrigendum: Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency?

Etablierung der Genomischen Erreger-Surveillance zur Stärkung des Pandemie- und Infektionsschutzes in Deutschland = Establishment of genomic pathogen surveillance to strengthen pandemic preparedness and infection prevention in Germany

Next-Generation Sequencing compared to standard microbiological diagnostics in ascitic fluid bacterial infections of ICU patients – establishment of a 16S rRNA NGS platform in low-biomass samples

Resolving colistin resistance and heteroresistance in Enterobacter species

SPATA2 regulates inflammation and cell death independently of CYLD

Sub-lethal signals in the mitochondrial apoptosis apparatus: pernicious by-product or physiological event?

Sub-lethal signals in the mitochondrial apoptosis apparatus: pernicious by-product or physiological event?

Mitochondria: intracellular sentinels of infections

GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation

Correction to: Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection

Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection

Chlamydia trachomatis inhibits apoptosis in infected cells by targeting the pro-apoptotic proteins Bax and Bak

The deubiquitinase Usp27x as a novel regulator of cFLIPL protein expression and sensitizer to death-receptor-induced apoptosis

Chlamydia trachomatis inhibits apoptosis in infected cells by targeting the pro-apoptotic proteins Bax and Bak

Correction to: Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection

Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency?

GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation

Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection

Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse

Surveillance and genomic analysis of third-generation cephalosporin-resistant and carbapenem-resistant klebsiella pneumoniae complex in Germany

The Coxiella burnetii T4SS effector protein AnkG hijacks the 7SK small nuclear ribonucleoprotein complex for reprogramming host cell transcription

The Coxiella burnetii T4SS effector protein AnkG hijacks the 7SK small nuclear ribonucleoprotein complex for reprogramming host cell transcription

The deubiquitinase Usp27x as a novel regulator of cFLIPL protein expression and sensitizer to death-receptor-induced apoptosis

Comprehensive integration of genome-wide association and gene expression studies reveals novel gene signatures and potential therapeutic targets for helicobacter pylori-induced gastric disease

Diversity of cell death signaling pathways in macrophages upon infection with modified vaccinia virus Ankara (MVA)

Host blood gene signatures can detect the progression to severe and cerebral malaria

Importance of Bcl-2-family proteins in murine hematopoietic progenitor and early B cells

Next- and third-generation sequencing outperforms culture-based methods in the diagnosis of ascitic fluid bacterial infections of ICU patients

Sub-lethal activation of the caspase-activated DNAse contributes to genomic instability and tumorigenesis during infection and inflammation

The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression

Antimicrobial susceptibility patterns and wild-type MIC distributions of anaerobic bacteria at a German university hospital: a five-year retrospective study (2015–2019)

Die Rolle von ausgewählten BH3-only Proteinen in der Lymphozytenentwicklung

Klinische Risikostratifizierung von Clostridioides difficile-Infektionen mittels PCR-basierter Nachweisverfahren

Point-of-care testing system for digital single cell detection of MRSA directly from nasal swabs

Protocol for a prospective cohort study: Prevention of Transmissions by Effective Colonisation Tracking in Neonates (PROTECT-Neo)

The innate lymphoid cell immune response in the mouse female genital tract upon infection with Chlamydia muridarum

Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim

A non‐death function of the mitochondrial apoptosis apparatus in immunity

Checkpoint kinase 1 is essential for fetal and adult hematopoiesis