Titel |
Clinical Metabolomics : Methods and Protocols / edited by Martin Giera, Elena Sánchez-López |
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Beteiligt |
Martin Giera (Herausgeber) |
Erschienen |
New York, NY: Springer US, Imprint: Humana |
Ausgabe |
2nd ed. 2025 |
Umfang |
Online-Ressource, XV, 575 p. 119 illus., 86 illus. in color. : online resource. |
Enthält |
(Pre)Clinical Metabolomics Analysis -- Global Metabolomics using LC-MS for Clinical Applications -- Modular, scalable and customizable LC-HRMS for exposomics -- Distinguishing artifactual fatty acid dimers from FAHFAs in untargeted LC-MS pipelines -- Advances in Chiral Metabolomic Profiling and Biomarker Discovery -- Stable Isotope Tracing Experiments using LC-MS -- Quantification of Total Ketone Bodies in biological matrices using Stable Isotope-labeled Internal Standards and RP-UPLC-MS/MS -- LC-MS/MS quantification of endocannabinoids in tissues -- Prostaglandin Metabolites Analysis in Urine by LC-MS/MS -- A method for analysis of oxidized phospholipids from biological samples using mass spectrometry -- Non-enzymatic oxidized polyunsaturated fatty acid products in human plasma and urine samples by LC-QTOF-MS/MS -- Reversed-Phase Ultrahigh-Performance Liquid Chromatography – Mass Spectrometry Method for High-Throughput Lipidomic Quantitation -- High-Throughput RPLC-MS/MS Quantification of Short- and Medium-Chain Fatty Acids -- Long chain base profiling with multiple reaction monitoring mass spectrometry -- Sphingolipid analysis in clinical research -- Recommendations for accurate lipid annotation and semi-absolute quantification from LC-MS/MS datasets -- Rapid analysis of Sterols in Blood Derived Samples -- Ultrahigh-Performance Supercritical Fluid Chromatography – Mass Spectrometry in the Clinical Lipidomic Analysis -- Quantification of octadecanoids in human plasma using chiral supercritical fluid chromatography-tandem mass spectrometry -- Rapid Lipid Mediator Profiling by Convergence Chromatography-MS/MS -- Analysis of the Mammalian Lipidome by DMS Shotgun Lipidomics -- Differential mobility spectrometry-based cardiolipin analysis -- CE-MS-based clinical metabolomics of human plasma -- Quantitative blood serum IVDr NMR spectroscopy in clinical metabolomics of cancer, neurodegeneration and internal medicine -- Lipoprotein (sub)fraction analysis on the Bruker B.I. LISA platform -- NMR-based stable isotope tracing of cancer metabolism -- NMR-based analysis of cellular central energy metabolism and exchange ratesIn Situ Isotope -- Tracing at Single-Cell Resolution Using Mass Spectrometry Imaging -- Extracting knowledge from MS clinical metabolomic data: Processing and analysis strategies -- Application of a computational metabolomics workflow for the diagnosis of inborn errors of metabolism in a laboratory setting |
ISBN |
978-1-0716-4116-3 |
Sprache |
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Land |
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Themengebiet |
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Thema |
Metabolic Pathways. |
DDC-Notation |
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Reihe |
Methods in Molecular Biology ; 2855 |
Persistent Identifier |
urn:nbn:de:101:1-2410030412251.149816820077 (URN) |
Datensatz-ID |
1343900611 |
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