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Thomas Müller (1966-)

Chemiker

Name	Thomas Müller
Zeit	1966- (Lebensdaten)
Ort	Würzburg (Geburtsort) Heidelberg (Wirkungsort) Deutschland
Geschlecht	männlich
Akademischer Grad bzw. Titel	Dr. med. habil.
Beruf	Chemiker (charakteristischer Beruf)
Variante	T. D. Müller Thomas D. Müller Thomas Dieter Müller Thomas D. Mueller
Weitere Angaben	Physiologische Chemie; tätig am Theodor-Boveri-Institut für Biowissenschaften (Biozentrum) der Universität Würzburg; European Molecular Biology Laboratory, Heidelberg
Datensatztyp	Person
GND-Nummer	13751512X
Datensatz-ID	13751512X
Beteiligt an alle anzeigen Design of glycoengineered IL-4 antagonists employing chemical and biosynthetic glycosylation In-vitro-Analyse der Glutamin-Restriktion im murinen Modellsystem L929 sowie des Einflusses potentieller caloric restriction mimetics auf das Plattenepithelkarzinom HNSCC Molecular forms of BMP15 and GDF9 in mammalian species that differ in litter size In Vitro Analyse der Glukose- und Methionin-Restriktion im humanen Modellsystem HeLa sowie im Plattenepithelkarzinom HNSCC Methionin-Restriktion als neue Strategie in der Tumortherapie des HNSCC Modulation of regulatory T cells for the immunotherapy of inflammatory diseases and cancer Site-directed immobilization of an engineered bone morphogenetic protein 2 (BMP2) variant to collagen-based microspheres induces bone formation in vivo The Role of FGF Receptor 2 in GDF5 mediated Signal Transduction Untersuchungen zur Bedeutung von Spaltprodukten des vaskulär endothelialen (VE-) Cadherin als Auslöser für die Schrankenstörung des Gefäßendothels In Vitro Analyse der Methionin-Restriktion im murinen Modellsystem L929 sowie im Platteneptihelkarzinom - HNSCC Design of novel IL-4 antagonists employing site-specific chemical and biosynthetic glycosylation Identification and structural analysis of the Schizosaccharomyces pombe SMN complex The Venus flytrap Dionaea muscipula counts prey-induced action potentials to induce sodium uptake Towards an understanding of the intricate interaction network of TFIIH Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion Specification of BMP signaling Die Bedeutung von Todesdomäne Adapterproteinen für die Signaltransduktion des TNFR1 und der TRAIL Todesrezeptoren Gene expression profiling of connective tissue growth factor (CTGF) stimulated primary human tenon fibroblasts reveals an inflammatory and wound healing response in vitro Glucagon-like peptide 1 (GLP-1) Proteomic Analysis of Excretory-Secretory Products of Mesocestoides corti Metacestodes Reveals Potential Suppressors of Dendritic Cell Functions Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion Design and validation of a disease network of inflammatory processes in the NSG-UC mouse model A hypomorphic BMPR1B mutation causes du Pan acromesomelic dysplasia Entwicklung und Charakterisierung von Gaussia princeps Luziferase-Antikörper-Fusionsproteinen Structural Characterization of the TFIIH Subunits p34 and p44 from C. thermophilum Interleukin‐4‐Clicked Surfaces Drive M2 Macrophage Polarization Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-Mediated Antagonism of Wnt/LRP6 Signaling Funktionelle Untersuchungen zur Oxylipin-abhängigen Regulation von Hitzeschockproteinen in \(Arabidopsis\) \(thaliana\) GDF-5 can act as a context-dependent BMP-2 antagonist Identification of a Novel TGF-beta-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-\(\beta\)-Receptor-3 (TGFR-3) Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid \(IL2Rγ^{null}\) mice engrafted with human peripheral blood mononuclear cells Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-Knot for Wnt-Signaling Inhibition Pan-Raf-Inhibition als neue therapeutische Strategie im Multiplen Myelom Regulation Tumornekrosefaktor (TNF) Rezeptor assoziierter Signalwege durch das Adapterprotein TRAF1 The Venus Flytrap Dionaea muscipula Counts Prey-Induced Action Potentials to Induce Sodium Uptak The hypervariable region 4 (HV4) and position 93 of the α chain modulate CD1d‐glycolipid binding of iNKT TCRs Die Bedeutung von TRAF2 bei TRAIL-induzierter Apoptose und Nekroptose Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2R \(γ^{null}\) mice engrafted with human peripheral blood mononuclear cells NOD-scid IL2R \(\gamma^{null}\) mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways Bambi – Charakterisierung eines inhibitorischen BMP-Pseudorezeptors Die Rolle der CD8+ T Zellen in der Pathogenese der Experimentellen Autoimmunen Enzephalomyelitis in der Lewis Ratte Twisted gastrulation - ein BMP-Modulatorprotein mit dualer Funktionalität A bone overgrowth disorder due to a gain-of-function mutation in the kinase homology domain of guanylyl cyclase B, the receptor for CNP NOD-scid IL2R γnull mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3) The Clip-Segment of the von Willebrand Domain 1 of the BMP Modulator Protein Crossveinless 2 Is Preformed A Selection Fit Mechanism in BMP Receptor IA as a Possible Source for BMP Ligand-Receptor Promiscuity Antagonist design through forced electrostatic mismatch Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy Receptor binding properties of four-helix-bundle growth factors deduced from electrostatic analysis Receptor oligomerization and beyond: a case study in bone morphogenetic proteins Mechanismen der molekularen Erkennung bei Protein-Protein-Interaktionen A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor Pyridinio‐isoalloxazinophanes as Model Systems for Active‐Site Complexes in Flavoenzymes: Syntheses, X‐Ray Structure Analyses and Spectroscopic Properties Cytokin - Rezeptorwechselwirkungen am Beispiel von Interleukin 4

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Katalog der Deutschen Nationalbibliothek

Thomas Müller (1966-)

Design of glycoengineered IL-4 antagonists employing chemical and biosynthetic glycosylation

In-vitro-Analyse der Glutamin-Restriktion im murinen Modellsystem L929 sowie des Einflusses potentieller caloric restriction mimetics auf das Plattenepithelkarzinom HNSCC

Molecular forms of BMP15 and GDF9 in mammalian species that differ in litter size

In Vitro Analyse der Glukose- und Methionin-Restriktion im humanen Modellsystem HeLa sowie im Plattenepithelkarzinom HNSCC

Methionin-Restriktion als neue Strategie in der Tumortherapie des HNSCC

Modulation of regulatory T cells for the immunotherapy of inflammatory diseases and cancer

Site-directed immobilization of an engineered bone morphogenetic protein 2 (BMP2) variant to collagen-based microspheres induces bone formation in vivo

The Role of FGF Receptor 2 in GDF5 mediated Signal Transduction

Untersuchungen zur Bedeutung von Spaltprodukten des vaskulär endothelialen (VE-) Cadherin als Auslöser für die Schrankenstörung des Gefäßendothels

In Vitro Analyse der Methionin-Restriktion im murinen Modellsystem L929 sowie im Platteneptihelkarzinom - HNSCC

Design of novel IL-4 antagonists employing site-specific chemical and biosynthetic glycosylation

Identification and structural analysis of the Schizosaccharomyces pombe SMN complex

The Venus flytrap Dionaea muscipula counts prey-induced action potentials to induce sodium uptake

Towards an understanding of the intricate interaction network of TFIIH

Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion

Specification of BMP signaling

Die Bedeutung von Todesdomäne Adapterproteinen für die Signaltransduktion des TNFR1 und der TRAIL Todesrezeptoren

Gene expression profiling of connective tissue growth factor (CTGF) stimulated primary human tenon fibroblasts reveals an inflammatory and wound healing response in vitro

Glucagon-like peptide 1 (GLP-1)

Proteomic Analysis of Excretory-Secretory Products of Mesocestoides corti Metacestodes Reveals Potential Suppressors of Dendritic Cell Functions

Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion

Design and validation of a disease network of inflammatory processes in the NSG-UC mouse model

A hypomorphic BMPR1B mutation causes du Pan acromesomelic dysplasia

Entwicklung und Charakterisierung von Gaussia princeps Luziferase-Antikörper-Fusionsproteinen

Structural Characterization of the TFIIH Subunits p34 and p44 from C. thermophilum

Interleukin‐4‐Clicked Surfaces Drive M2 Macrophage Polarization

Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-Mediated Antagonism of Wnt/LRP6 Signaling

Funktionelle Untersuchungen zur Oxylipin-abhängigen Regulation von Hitzeschockproteinen in \(Arabidopsis\) \(thaliana\)

GDF-5 can act as a context-dependent BMP-2 antagonist

Identification of a Novel TGF-beta-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-\(\beta\)-Receptor-3 (TGFR-3)

Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid \(IL2Rγ^{null}\) mice engrafted with human peripheral blood mononuclear cells

Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-Knot for Wnt-Signaling Inhibition

Pan-Raf-Inhibition als neue therapeutische Strategie im Multiplen Myelom

Regulation Tumornekrosefaktor (TNF) Rezeptor assoziierter Signalwege durch das Adapterprotein TRAF1

The Venus Flytrap Dionaea muscipula Counts Prey-Induced Action Potentials to Induce Sodium Uptak

The hypervariable region 4 (HV4) and position 93 of the α chain modulate CD1d‐glycolipid binding of iNKT TCRs

Die Bedeutung von TRAF2 bei TRAIL-induzierter Apoptose und Nekroptose

Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2R \(γ^{null}\) mice engrafted with human peripheral blood mononuclear cells

NOD-scid IL2R \(\gamma^{null}\) mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways

Bambi – Charakterisierung eines inhibitorischen BMP-Pseudorezeptors

Die Rolle der CD8+ T Zellen in der Pathogenese der Experimentellen Autoimmunen Enzephalomyelitis in der Lewis Ratte

Twisted gastrulation - ein BMP-Modulatorprotein mit dualer Funktionalität

A bone overgrowth disorder due to a gain-of-function mutation in the kinase homology domain of guanylyl cyclase B, the receptor for CNP

NOD-scid IL2R γnull mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways

Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3)

The Clip-Segment of the von Willebrand Domain 1 of the BMP Modulator Protein Crossveinless 2 Is Preformed

A Selection Fit Mechanism in BMP Receptor IA as a Possible Source for BMP Ligand-Receptor Promiscuity

Antagonist design through forced electrostatic mismatch

Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy

Receptor binding properties of four-helix-bundle growth factors deduced from electrostatic analysis

Receptor oligomerization and beyond: a case study in bone morphogenetic proteins

Mechanismen der molekularen Erkennung bei Protein-Protein-Interaktionen

A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor

A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor

Pyridinio‐isoalloxazinophanes as Model Systems for Active‐Site Complexes in Flavoenzymes: Syntheses, X‐Ray Structure Analyses and Spectroscopic Properties

Cytokin - Rezeptorwechselwirkungen am Beispiel von Interleukin 4