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Dina Robaa (1978-)

Apothekerin

Name	Dina Robaa
Time	1978- (Date of birth and death)
Place	Halle (Saale) (Wirkungsort) Ägypten Deutschland
Academic degree	Dr. rer. nat.
Profession	Apothekerin (characteristic profession)
Further information	wissenschaftliche Mitarbeiterin, Universität Halle (Saale), Institut für Pharmazie, Institutsbereich Pharmazeutische Chemie und Klinische Pharmazie, Abteilung Medizinische Chemie
Record type	Person
GND-Identifier	1013717651
Record ID	1013717651
Involved in show all Utilization of an optimized AlphaFold protein model for structure‐based design of a selective HDAC11 inhibitor with anti‐neuroblastoma activity Direct GPCR-EGFR interaction enables synergistic membrane-to-nucleus information transfer Aromatic amino acid hydroxylases as off-targets of histone deacetylase inhibitors Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement ** Design, synthesis and biological characterization of histone deacetylase 8 (HDAC8) proteolysis targeting chimeras (PROTACs) with anti-neuroblastoma activity First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement Exploring aromatic cage flexibility of the histone methyllysine reader protein Spindlin1 and its impact on binding mode prediction: an in silico study Strategies To Design Selective Histone Deacetylase Inhibitors Structure-based design, docking and binding free energy calculations of A366 derivatives as spindlin1 inhibitors HaloTag‐targeted sirtuin‐rearranging ligand (SirReal) for the development of proteolysis‐targeting chimeras (PROTACs) against the lysine deacetylase sirtuin 2 (Sirt2) Proteolysis targeting chimeras (PROTACs) for epigenetics research Opening the Selectivity Pocket in the Human Lysine Deacetylase Sirtuin2 – New Opportunities, New Questions Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as Sm HDAC8 Inhibitors for the Treatment of Schistosomiasis A novel class of Schistosoma mansoni histone deacetylase 8 (HDAC8) inhibitors identified by structure-based virtual screening and in vitro testing Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells Pyrido- and benzisothiazolones as inhibitors of histone acetyltransferases (HATs) Novel benzidoloazecines and dibenzazecines : synthesis and affinities for the dopamine receptors Novel Benzindoloazecines and Dibenzazecines : Synthesis and Affinities for the Dopamine Receptors

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Dina Robaa (1978-)

Utilization of an optimized AlphaFold protein model for structure‐based design of a selective HDAC11 inhibitor with anti‐neuroblastoma activity

Direct GPCR-EGFR interaction enables synergistic membrane-to-nucleus information transfer

Aromatic amino acid hydroxylases as off-targets of histone deacetylase inhibitors

Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages

First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement **

Design, synthesis and biological characterization of histone deacetylase 8 (HDAC8) proteolysis targeting chimeras (PROTACs) with anti-neuroblastoma activity

First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement

Exploring aromatic cage flexibility of the histone methyllysine reader protein Spindlin1 and its impact on binding mode prediction: an in silico study

Strategies To Design Selective Histone Deacetylase Inhibitors

Structure-based design, docking and binding free energy calculations of A366 derivatives as spindlin1 inhibitors

HaloTag‐targeted sirtuin‐rearranging ligand (SirReal) for the development of proteolysis‐targeting chimeras (PROTACs) against the lysine deacetylase sirtuin 2 (Sirt2)

Proteolysis targeting chimeras (PROTACs) for epigenetics research

Opening the Selectivity Pocket in the Human Lysine Deacetylase Sirtuin2 – New Opportunities, New Questions

Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as Sm HDAC8 Inhibitors for the Treatment of Schistosomiasis

A novel class of Schistosoma mansoni histone deacetylase 8 (HDAC8) inhibitors identified by structure-based virtual screening and in vitro testing

Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells

Pyrido- and benzisothiazolones as inhibitors of histone acetyltransferases (HATs)

Novel benzidoloazecines and dibenzazecines : synthesis and affinities for the dopamine receptors

Novel Benzindoloazecines and Dibenzazecines : Synthesis and Affinities for the Dopamine Receptors