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Dirk Grimm

Biologe

Name	Dirk Grimm
Place	Deutschland
Gender	männlich
Academic degree	Prof. Dr.
Profession	Biologe (characteristic profession)
Related	BioQuant
Further information	Zentrum für Infektiologie; Bioquant; Exzellenzcluster CellNetworks, Universität Heidelberg
Record type	Person
GND-Identifier	1016476671
Record ID	1016476671
Involved in show all Split intein-mediated protein trans-splicing to express large dystrophins Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2 Cofactor-modified RNAs and their identification : introducing the novel 5'-thiamine cap structure and HELIOS NAD-Seq, a next generation protocol for the identification of 5'-NAD-capped RNA Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9 Substrate Stiffness and Particle Properties Influence Cellular Uptake of Nanoparticles and Viruses from the Ventral Side Membrane remodelling triggers maturation of excitation–contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice Induction of hepatitis E virus anti-ORF3 antibodies from systemic administration of a muscle-specific adeno-associated virus (AAV) vector Towards an RNA interference and Adeno-associated virus-based gene therapy targeting hepatitis E virus Development of an AAV9-RNAi-mediated silencing strategy to abrogate TRPM4 expression in the adult heart The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9 AAV vector-mediated in vivo reprogramming into pluripotency MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB Split Cas9, Not Hairs − Advancing the Therapeutic Index of CRISPR Technology Next-generation AAV vectors for clinical use: an ever-accelerating race Blocking sense‐strand activity improves potency, safety and specificity of anti‐hepatitis B virus short hairpin RNA TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining T160‐phosphorylated CDK 2 defines threshold for HGF ‐dependent proliferation in primary hepatocytes CRISPR genome engineering and viral gene delivery: A case of mutual attraction Everybody wins! Poland hosts thrilling competitions of viruses, RNAi and football teams Entwicklung und Anwendung neuartiger Methoden zur Produktion, Reinigung und Titration rekombinanter Adeno-assoziierter Viren des Typ 2

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Katalog der Deutschen Nationalbibliothek

Dirk Grimm

Split intein-mediated protein trans-splicing to express large dystrophins

Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2

Cofactor-modified RNAs and their identification : introducing the novel 5'-thiamine cap structure and HELIOS NAD-Seq, a next generation protocol for the identification of 5'-NAD-capped RNA

Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9

Substrate Stiffness and Particle Properties Influence Cellular Uptake of Nanoparticles and Viruses from the Ventral Side

Membrane remodelling triggers maturation of excitation–contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes

In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice

Induction of hepatitis E virus anti-ORF3 antibodies from systemic administration of a muscle-specific adeno-associated virus (AAV) vector

Towards an RNA interference and Adeno-associated virus-based gene therapy targeting hepatitis E virus

Development of an AAV9-RNAi-mediated silencing strategy to abrogate TRPM4 expression in the adult heart

The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner

Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments

Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9

AAV vector-mediated in vivo reprogramming into pluripotency

MAP3K7 is recurrently deleted in pediatric T-lymphoblastic leukemia and affects cell proliferation independently of NF-κB

Split Cas9, Not Hairs − Advancing the Therapeutic Index of CRISPR Technology

Next-generation AAV vectors for clinical use: an ever-accelerating race

Blocking sense‐strand activity improves potency, safety and specificity of anti‐hepatitis B virus short hairpin RNA

TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus

Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining

T160‐phosphorylated CDK 2 defines threshold for HGF ‐dependent proliferation in primary hepatocytes

CRISPR genome engineering and viral gene delivery: A case of mutual attraction

Everybody wins! Poland hosts thrilling competitions of viruses, RNAi and football teams

Entwicklung und Anwendung neuartiger Methoden zur Produktion, Reinigung und Titration rekombinanter Adeno-assoziierter Viren des Typ 2