Detail page

Knowledge Web

Person

Dieter Willbold (1965-)

Biochemiker

Name	Dieter Willbold
Time	1965- (Date of birth and death)
Place	Deutschland
Gender	männlich
Academic degree	Prof. Dr.
Profession	Biochemiker (characteristic profession) Hochschullehrer Sachverständiger
Related	Heinrich-Heine-Universität Düsseldorf. Mathematisch-Naturwissenschaftliche Fakultät (Fachbereich Biologie) Forschungszentrum Jülich Heinrich-Heine-Universität Düsseldorf. Institut für Physikalische Biologie
Further information	Seit 2004 Professor (C4) für Physikalische Biologie an der Heinrich-Heine-Universität in Düsseldorf. Zusätzlich (seit 2005): Direktor beim Institut für Strukturbiologie (INB-2) am Forschungszentrum Juelich
Record type	Person
GND-Identifier	1018389911
Record ID	1018389911
Involved in show all Blood-based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer’s disease Oral Treatment with d-RD2RD2 Impedes Early Disease Mechanisms in SOD1*G93A Transgenic Mice but Does Not Prolong Survival Residue alterations within a conserved hydrophobic pocket influence light, oxygen, voltage photoreceptor dark recovery The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors Alpha-synuclein-specific naturally occurring antibodies inhibit aggregation in vitro and in vivo The modulating effect of soluble amyloid-β dimers on amyloid-β aggregation in vivo and in vitro A Novel Anti-Inflammatory d-Peptide Inhibits Disease Phenotype Progression in an ALS Mouse Model Comparison of the Amyloid Load in the Brains of Two Transgenic Alzheimer's Disease Mouse Models Quantified by Florbetaben Positron Emission Tomography Glutamic acid-rich proteins of rod photoreceptors are natively unfolded Oral Treatment with RD2RD2 Impedes Development of Motoric Phenotype and Delays Symptom Onset in SOD1(G93A) Transgenic Mice PEAβ Triggers Cognitive Decline and Amyloid Burden in a Novel Mouse Model of Alzheimer’s Disease Sex-Related Motor Deficits in the Tau-P301L Mouse Model Viral rhodopsins 1 are an unique family of light-gated cation channels Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils Na+ signaling in white matter glial cells Untersuchungen zur Metabolisierung therapeutisch aktiver D-Peptide Untersuchungen zur Rolle N-terminaler Peptidmodifikationen bei dementiellen Erkrankungen sowie daraus folgende Ansätze zur Unterdrückung pathophysiologischer Prozesse A near atomic-scale view at the composition of amyloid-beta fibrils by atom probe tomography Aβ Oligomer Elimination Restores Cognition in Transgenic Alzheimer’s Mice with Full-blown Pathology Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation Automatisierte Quantifizierung proteinöser Partikel In Vitro Reconstitution of the Highly Active and Natively Folded Recombinant Human Superoxide Dismutase 1 Holoenzyme Aβ Oligomer Elimination Restores Cognition in Transgenic Alzheimer’s Mice with Full-blown Pathology Einfluss von Thrombozyten auf die Progression der Alzheimer Erkrankung In vivo Charakterisierung Amyloid-β-Oligomer eliminierender D-enantiomerer Peptide zur Therapie der Alzheimer’schen Demenz Pharmakokinetische Charakterisierung D-enantiomerer Peptide zur Therapie der Alzheimer'schen Demenz Preclinical pharmacokinetics and cerebral distribution of D-enantiomeric peptides for the treatment of Alzheimer’s disease Untersuchung der Enzymkatalyse und Protein-Ligand Wechselwirkung unter Verwendung von Flüssig-NMR-Spektroskopie 1H, 13C, and 15N backbone and sidechain resonance assignments of a monomeric variant of E. coli deoxyribose-5-phosphate aldolase Erratum to: High-Resolution Structure of a Membrane Protein Transferred from Amphipol to a Lipidic Mesophase Analysis of anticoagulants for blood-based quantitation of amyloid β oligomers in the sFIDA assay Charakterisierung der Interaktion von β-Amyloid mit Membranen mittels Nanodisks als Modellmembransystem Die Rolle des Lektins LecB in der Physiologie und Pathogenität von Pseudomonas aeruginosa Etablierung eines hiPS-basierten in vitro Modells zur Untersuchung von umwelt- und genetisch-bedingten Störungen neuraler Entwicklungsprozesse Investigation of amyloid beta peptide aggregation by small angle neutron scattering and complementary methods Iron-sulfur cluster coordinating Glutaredoxins in neuroinflammatory degeneration and regeneration Regulation of autophagy upon vaccinia virus infection Structural analysis and aggregation of Alzheimer’s disease related pyroglutamate-modified amyloid-β Structural characterisation of autophagy-related protein LC3C Structure and conformational fluctuations of Phage T4 Lysozyme under native and denaturing conditions The Kinetics of α-Synuclein Aggregation: Single Fibril Growth, β1-β2 Contacts, Membrane Environments and Dityrosine Formation Acute and Chronic Volume Changes in Astrocytes Biophysikalische Charakterisierung der Interaktion von Nanoobjekten, peptidbasierten Medikamentenprototypen und dem Amyloid-beta-Peptid Charakterisierung autokriner Mechanismen in der Regulation des Gallensalztransporters BSEP durch pro-inflammatorische Mediatoren wie IL-1β Charakterisierung der Relevanz der MK2 für die Akut-Phase-Reaktion Evaluation von D-enantiomeren Peptiden als mögliche Wirkstoffkandidaten in einem Alzheimer-Mausmodell Fluorescence fluctuation-based analysis of the amyloid-beta monomer Modeling behavioral and neuropathological phenotypes of brain diseases using in utero electroporation Modeling DISC1-dependent chronic mental illnesses in vivo and in vitro: generation of a novel DISC1 transgenic rat NMR-spektroskopische Charakterisierung der Dynamik des Autophagie-relevanten Proteins GABARAP auf verschiedenen Zeitskalen Pharmacokinetic properties of D-peptides designed for treatment of Alzheimer’s disease Selection and characterization of Amyloid-β1-42 binding D-enantiomeric peptides for potential therapeutic intervention of Alzheimer´s disease Selection and Characterization of Tau Binding ᴅ-Enantiomeric Peptides with Potential for Therapy of Alzheimer Disease Weiterentwicklung und Anwendung des sFIDA-Assays zur Frühdiagnose der Alzheimerschen Demenz mittels Abeta-Oligomeren als möglicher Biomarker Sequence-specific 1H, 15N, and 13C resonance assignments of the autophagy-related protein LC3C Structure and function of a short LOV protein from the marine phototrophic bacterium Dinoroseobacter shibae

Please note

The beta version does not yet contain all functions and information of the DNB portal catalogue. If you are missing information or want to order a medium, please visit the page in the DNB portal catalogue via the following link:

Katalog der Deutschen Nationalbibliothek

Dieter Willbold (1965-)

Blood-based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects

Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer’s disease

Oral Treatment with d-RD2RD2 Impedes Early Disease Mechanisms in SOD1*G93A Transgenic Mice but Does Not Prolong Survival

Residue alterations within a conserved hydrophobic pocket influence light, oxygen, voltage photoreceptor dark recovery

The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors

Alpha-synuclein-specific naturally occurring antibodies inhibit aggregation in vitro and in vivo

The modulating effect of soluble amyloid-β dimers on amyloid-β aggregation in vivo and in vitro

A Novel Anti-Inflammatory d-Peptide Inhibits Disease Phenotype Progression in an ALS Mouse Model

Comparison of the Amyloid Load in the Brains of Two Transgenic Alzheimer's Disease Mouse Models Quantified by Florbetaben Positron Emission Tomography

Glutamic acid-rich proteins of rod photoreceptors are natively unfolded

Oral Treatment with RD2RD2 Impedes Development of Motoric Phenotype and Delays Symptom Onset in SOD1(G93A) Transgenic Mice

PEAβ Triggers Cognitive Decline and Amyloid Burden in a Novel Mouse Model of Alzheimer’s Disease

Sex-Related Motor Deficits in the Tau-P301L Mouse Model

Viral rhodopsins 1 are an unique family of light-gated cation channels

Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils

Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers

The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels

An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils

Na+ signaling in white matter glial cells

Untersuchungen zur Metabolisierung therapeutisch aktiver D-Peptide

Untersuchungen zur Rolle N-terminaler Peptidmodifikationen bei dementiellen Erkrankungen sowie daraus folgende Ansätze zur Unterdrückung pathophysiologischer Prozesse

A near atomic-scale view at the composition of amyloid-beta fibrils by atom probe tomography

Aβ Oligomer Elimination Restores Cognition in Transgenic Alzheimer’s Mice with Full-blown Pathology

Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation

Automatisierte Quantifizierung proteinöser Partikel

In Vitro Reconstitution of the Highly Active and Natively Folded Recombinant Human Superoxide Dismutase 1 Holoenzyme

Aβ Oligomer Elimination Restores Cognition in Transgenic Alzheimer’s Mice with Full-blown Pathology

Einfluss von Thrombozyten auf die Progression der Alzheimer Erkrankung

In vivo Charakterisierung Amyloid-β-Oligomer eliminierender D-enantiomerer Peptide zur Therapie der Alzheimer’schen Demenz

Pharmakokinetische Charakterisierung D-enantiomerer Peptide zur Therapie der Alzheimer'schen Demenz

Preclinical pharmacokinetics and cerebral distribution of D-enantiomeric peptides for the treatment of Alzheimer’s disease

Untersuchung der Enzymkatalyse und Protein-Ligand Wechselwirkung unter Verwendung von Flüssig-NMR-Spektroskopie

1H, 13C, and 15N backbone and sidechain resonance assignments of a monomeric variant of E. coli deoxyribose-5-phosphate aldolase

Erratum to: High-Resolution Structure of a Membrane Protein Transferred from Amphipol to a Lipidic Mesophase

Analysis of anticoagulants for blood-based quantitation of amyloid β oligomers in the sFIDA assay

Charakterisierung der Interaktion von β-Amyloid mit Membranen mittels Nanodisks als Modellmembransystem

Die Rolle des Lektins LecB in der Physiologie und Pathogenität von Pseudomonas aeruginosa

Etablierung eines hiPS-basierten in vitro Modells zur Untersuchung von umwelt- und genetisch-bedingten Störungen neuraler Entwicklungsprozesse

Investigation of amyloid beta peptide aggregation by small angle neutron scattering and complementary methods

Iron-sulfur cluster coordinating Glutaredoxins in neuroinflammatory degeneration and regeneration

Regulation of autophagy upon vaccinia virus infection

Structural analysis and aggregation of Alzheimer’s disease related pyroglutamate-modified amyloid-β

Structural characterisation of autophagy-related protein LC3C

Structure and conformational fluctuations of Phage T4 Lysozyme under native and denaturing conditions

The Kinetics of α-Synuclein Aggregation: Single Fibril Growth, β1-β2 Contacts, Membrane Environments and Dityrosine Formation

Acute and Chronic Volume Changes in Astrocytes

Biophysikalische Charakterisierung der Interaktion von Nanoobjekten, peptidbasierten Medikamentenprototypen und dem Amyloid-beta-Peptid

Charakterisierung autokriner Mechanismen in der Regulation des Gallensalztransporters BSEP durch pro-inflammatorische Mediatoren wie IL-1β

Charakterisierung der Relevanz der MK2 für die Akut-Phase-Reaktion

Evaluation von D-enantiomeren Peptiden als mögliche Wirkstoffkandidaten in einem Alzheimer-Mausmodell

Fluorescence fluctuation-based analysis of the amyloid-beta monomer

Modeling behavioral and neuropathological phenotypes of brain diseases using in utero electroporation

Modeling DISC1-dependent chronic mental illnesses in vivo and in vitro: generation of a novel DISC1 transgenic rat

NMR-spektroskopische Charakterisierung der Dynamik des Autophagie-relevanten Proteins GABARAP auf verschiedenen Zeitskalen

Pharmacokinetic properties of D-peptides designed for treatment of Alzheimer’s disease

Selection and characterization of Amyloid-β1-42 binding D-enantiomeric peptides for potential therapeutic intervention of Alzheimer´s disease

Selection and Characterization of Tau Binding ᴅ-Enantiomeric Peptides with Potential for Therapy of Alzheimer Disease

Weiterentwicklung und Anwendung des sFIDA-Assays zur Frühdiagnose der Alzheimerschen Demenz mittels Abeta-Oligomeren als möglicher Biomarker

Sequence-specific 1H, 15N, and 13C resonance assignments of the autophagy-related protein LC3C

Structure and function of a short LOV protein from the marine phototrophic bacterium Dinoroseobacter shibae