Detail page

Knowledge Web

Person

Christel Herold-Mende

Ärztin

Name	Christel Herold-Mende
Place	Deutschland
Gender	weiblich
Academic degree	Prof., Dr. rer. nat.
Profession	Ärztin (characteristic profession)
Variant	Christel Herold- Mende Christel C. Herold-Mende Christel C. Herold- Mende
Further information	Leiterin der AG Molekulare Zellbiologie an der Hals-Nasen-Ohren-Klinik des Universitätsklinikums Heidelberg; Sektionsleitung Experimentelle Neurochirurgie der Neurochirurgischen Klinik des Universitätsklinikums Heidelberg (Stand: 2016). Ab 30.10.2012 Neurochirurgische Universitätsklinik Heidelberg
Record type	Person
GND-Identifier	1022936549
Record ID	1022936549
Involved in show all A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1 Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T: evaluation of a modeling workflow EMP3 sustains oncogenic EGFR/CDK2 signaling by restricting receptor degradation in glioblastoma Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics scSNPdemux: a sensitive demultiplexing pipeline using single nucleotide polymorphisms for improved pooled single-cell RNA sequencing analysis Combining organotypic tissue culture with multi-color fluorescence light-sheet microscopy (OTCxLSFM) a novel tool to study glioma invasion/migration Evaluation of targeted anti-cancer drugs for the treatment of aggressive meningiomas STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma Single-cell DNA sequencing reveals order of mutational acquisition in TRAF7/AKT1 and TRAF7/KLF4 mutant meningiomas Luminescent Pyrrole‐Based Phosphaphenalene Gold Complexes: Versatile Anticancer Tools with Wide Applicability Luminescent Pyrrole‐Based Phosphaphenalene Gold Complexes: Versatile Anticancer Tools with Wide Applicability Luminescent Pyrrole‐Based Phosphaphenalene Gold Complexes: Versatile Anticancer Tools with Wide Applicability Rapid-CNS2: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival CHRDL1 regulates stemness in glioma stem-like cells Integrated metabolomics and transcriptomics analysis of monolayer and neurospheres from established glioblastoma cell lines Multi-omics analysis of genetically defined glioblastoma organoid models reveals novel principles of tumor development and targets for personalized treatment Novel therapies for meningiomas in vitro and in vivo STAT3 enhances sensitivity of glioblastoma to drug-induced autophagy-dependent cell death The genomic and transcriptional landscape of primary central nervous system lymphoma Oligosarcomas, IDH-mutant are distinct and aggressive A new pentafluorothio-substituted curcuminoid with superior antitumor activity Calcitriol promotes differentiation of glioma stem-like cells and increases their susceptibility to temozolomide Effektor-T-Zellinfiltration in Plattenepithelkarzinome des Kopf-Hals-Bereichs Einfluss der Lagebeziehung primärer Glioblastome zur subventrikulären Zone auf die Expression neuraler Stammzellmarker und das Patientenüberleben Identifizierung und Charakterisierung differenziell exprimierter Gene in Kopf-Hals-Plattenepithelkarzinomen von Lang- und Kurzzeitüberlebern T-Zellinfiltration und Tumormikromilieu in Hirnmetastasen des bronchialen Adenokarzinoms The anesthetist’s choice of inhalational vs. intravenous anesthetics has no impact on survival of glioblastoma patients Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1 AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion Metabolic plasticity of IDH1-mutant glioma cell lines is responsible for low sensitivity to glutaminase inhibition CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas YAP1-fusions in pediatric NF2-wildtype meningioma YAP1-fusions in pediatric NF2-wildtype meningioma Microscopic brain invasion in meningiomas previously classified as WHO grade I is not associated with patient outcome Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities Intraventricular meningiomas frequently harbor NF2 mutations but lack common genetic alterations in TRAF7, AKT1, SMO, KLF4, PIK3CA, and TERT MYCN amplification drives an aggressive form of spinal ependymoma Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions Volumetric assessment of glioblastoma and its predictive value for survival Impact of post-surgical freezing delay on brain tumor metabolomics Mutational patterns and regulatory networks in epigenetic subgroups of meningioma RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment PET/CT Imaging of NSCLC with a αvβ6 Integrin-Targeting Peptide Evolutionary trajectories of IDHWT glioblastomas reveal a common path of early tumorigenesis instigated years ahead of initial diagnosis Identification of KIF11 as a novel target in meningioma Mutational patterns and regulatory networks in epigenetic subgroups of meningioma RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions Novel, improved grading system(s) for IDH-mutant astrocytic gliomas Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations

Please note

The beta version does not yet contain all functions and information of the DNB portal catalogue. If you are missing information or want to order a medium, please visit the page in the DNB portal catalogue via the following link:

Katalog der Deutschen Nationalbibliothek

Christel Herold-Mende

A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1

Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T: evaluation of a modeling workflow

EMP3 sustains oncogenic EGFR/CDK2 signaling by restricting receptor degradation in glioblastoma

Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics

scSNPdemux: a sensitive demultiplexing pipeline using single nucleotide polymorphisms for improved pooled single-cell RNA sequencing analysis

Combining organotypic tissue culture with multi-color fluorescence light-sheet microscopy (OTCxLSFM) a novel tool to study glioma invasion/migration

Evaluation of targeted anti-cancer drugs for the treatment of aggressive meningiomas

STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death

Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas

PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma

Single-cell DNA sequencing reveals order of mutational acquisition in TRAF7/AKT1 and TRAF7/KLF4 mutant meningiomas

Luminescent Pyrrole‐Based Phosphaphenalene Gold Complexes: Versatile Anticancer Tools with Wide Applicability

Luminescent Pyrrole‐Based Phosphaphenalene Gold Complexes: Versatile Anticancer Tools with Wide Applicability

Luminescent Pyrrole‐Based Phosphaphenalene Gold Complexes: Versatile Anticancer Tools with Wide Applicability

Rapid-CNS2: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study

Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival

CHRDL1 regulates stemness in glioma stem-like cells

Integrated metabolomics and transcriptomics analysis of monolayer and neurospheres from established glioblastoma cell lines

Multi-omics analysis of genetically defined glioblastoma organoid models reveals novel principles of tumor development and targets for personalized treatment

Novel therapies for meningiomas in vitro and in vivo

STAT3 enhances sensitivity of glioblastoma to drug-induced autophagy-dependent cell death

The genomic and transcriptional landscape of primary central nervous system lymphoma

Oligosarcomas, IDH-mutant are distinct and aggressive

A new pentafluorothio-substituted curcuminoid with superior antitumor activity

Calcitriol promotes differentiation of glioma stem-like cells and increases their susceptibility to temozolomide

Effektor-T-Zellinfiltration in Plattenepithelkarzinome des Kopf-Hals-Bereichs

Einfluss der Lagebeziehung primärer Glioblastome zur subventrikulären Zone auf die Expression neuraler Stammzellmarker und das Patientenüberleben

Identifizierung und Charakterisierung differenziell exprimierter Gene in Kopf-Hals-Plattenepithelkarzinomen von Lang- und Kurzzeitüberlebern

T-Zellinfiltration und Tumormikromilieu in Hirnmetastasen des bronchialen Adenokarzinoms

The anesthetist’s choice of inhalational vs. intravenous anesthetics has no impact on survival of glioblastoma patients

Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

Metabolic plasticity of IDH1-mutant glioma cell lines is responsible for low sensitivity to glutaminase inhibition

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas

YAP1-fusions in pediatric NF2-wildtype meningioma

YAP1-fusions in pediatric NF2-wildtype meningioma

Microscopic brain invasion in meningiomas previously classified as WHO grade I is not associated with patient outcome

Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities

Intraventricular meningiomas frequently harbor NF2 mutations but lack common genetic alterations in TRAF7, AKT1, SMO, KLF4, PIK3CA, and TERT

MYCN amplification drives an aggressive form of spinal ependymoma

Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions

Volumetric assessment of glioblastoma and its predictive value for survival

Impact of post-surgical freezing delay on brain tumor metabolomics

Mutational patterns and regulatory networks in epigenetic subgroups of meningioma

RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas

DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment

PET/CT Imaging of NSCLC with a αvβ6 Integrin-Targeting Peptide

Evolutionary trajectories of IDHWT glioblastomas reveal a common path of early tumorigenesis instigated years ahead of initial diagnosis

Identification of KIF11 as a novel target in meningioma

Mutational patterns and regulatory networks in epigenetic subgroups of meningioma

RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas

Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p

Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma

Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions

Novel, improved grading system(s) for IDH-mutant astrocytic gliomas

Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations