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Ralf Bartenschlager (1958-)

Name	Ralf Bartenschlager
Time	1958- (Date of birth and death)
Place	Heidelberg (Wirkungsort) Deutschland
Gender	männlich
Academic degree	Prof. Dr. rer. nat.
Variant	Ralf F. W. Bartenschlager R. F. W. Bartenschlager
Related	Zentrum für Infektiologie. AG Bartenschlager (seit 02/2002) Deutsche Akademie der Naturforscher Leopoldina (Mitglied, Matrikelnummer 07538) (2013-) Virologie (Thema)
Further information	1990 Promotion in Heidelberg; Virologe und Leitender Direktor der Molekularen Virologie im Department für Infektiologie, Universitätsklinikum Heidelberg
Record type	Person
GND-Identifier	1058097989
Record ID	1058097989
Involved in show all Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens Cell‐Penetrating Peptide‐Bismuth Bicycles Cell‐Penetrating Peptide‐Bismuth Bicycles A decade after the Nagoya Protocol – German biodiversity researchers’ perspective. Statement of the Permanent Senate Commission on Fundamental Issues of Biological Diversity (SKBV) of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) Elucidation of the mechanism-of-action of highly potent Dengue virus NS4B inhibitors JNJ-A07 and JNJ-1802 Investigating Fungi- Mammalian Host Interactions in Health and Disease Using Organoids and Mouse Models Stress Signaling Heterogeneity in Normal and Malignant Hematopoiesis The Impact of Cycling Hypoxia on the Phenotype of HPV-Positive Cervical Cancer Cells Virus Venetian Masked Ball: Does the Hepatitis Delta Virus Use Different Helper Viruses? Zika virus remodelled ER membranes contain proviral factors involved in redox and methylation pathways SARS-CoV-2 nsp3 and nsp4 are minimal constituents of a pore spanning replication organelle Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly Context-specific Roles of Infections and Interferons in Hematopoiesis and Myeloid Neoplasms Endoplasmic reticulum stress sensor ATF6 as an immunometabolic modulator in hepatic tumorigenesis Functional and biochemical characterization of viral and host factors involved in the Zika virus replication cycle Intercellular transmission of viral RNA by Apolipoprotein E-associated extracellular vesicles Live‐virus neutralization of the omicron variant in children and adults 14 months after SARS‐CoV‐2 wild‐type infection Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style Uncovering a novel role for iron regulatory proteins (IRPs) in adult murine neutropoiesis Deciphering the molecular regulation of the antiviral deaminase APOBEC3B Functional and morphological analysis of hepatitis C virus assembly Functional importance of the lipid kinase phosphatidylinositol 4-kinase III alpha on cytoskeletal organization and its impact on hepatitis C virus-induced liver pathogenesis HOST FACTORS ASSOCIATED WITH HEPATITIS B VIRUS LIFE-CYCLE: INSIDE AND OUT Production and characterization of novel BMMF2 rep-specific antibodies and application in cancer histology Role of LGP2 in the Innate Immune System upon Viral Infections Temporal control of the integrated stress response by a stochastic molecular switch The role of tumor suppressor genes PBRM1 and RPS6KA3 in primary liver cancer A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2 Interferon‐induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20 SARS‐CoV‐2 infection remodels the host protein thermal stability landscape Dimer Organization of Membrane‐Associated NS5A of Hepatitis C Virus as Determined by Highly Sensitive 1 H‐Detected Solid‐State NMR Dysregulated MicroRNAs in Biliary Tract Cancer and Characterization of the Target Tumor Suppressor FHL1 Image analysis in volume SEM datasets Influence of low oxygen concentrations on barrier function and intrinsic innate immune signaling in the human intestinal mucosa KDM6A is an epigenetic gatekeeper of mTORC1 signaling in cancer Role of class III PI3-kinase in double membrane vesicle formation associated with HCV and SARS-CoV-2 replication SARS-CoV-2 infection remodels the host protein thermal stability landscape The role of tumor cell-expressed Angiopoietin 2 in malignant melanoma The SAT Protein of the Minute Virus of Mice Induces the Lysis of the Cell through the Formation of Viroporin-like Structures SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography A Randomized Open label Phase-II Clinical Trial with or without Infusion of Plasma from Subjects after Convalescence of SARS-CoV-2 Infection in High-Risk Patients with Confirmed Severe SARS-CoV-2 Disease (RECOVER): A structured summary of a study protocol for a randomised controlled trial Structures and distributions of SARS-CoV-2 spike proteins on intact virions Proton‐Detected Solid‐State NMR of the Cell‐Free Synthesized α‐Helical Transmembrane Protein NS4B from Hepatitis C Virus A Coupled Mathematical Model of the Intracellular Replication of Dengue Virus and the Host Cell Immune Response to Infection A SYSTEM TO SEGMENT THE ROLE OF HYALURONIC ACID DURING RE-EPITHELIALIZATION Deciphering TCR signaling in metabolically activated T-cells in NASH and liver cancer development Determinants of efficient Hepatitis C Virus RNA replication in cell culture Early phlebovirus host cell interactions: The small GTPase Rab11 and the autophagic factor Atg7 promote Uukuniemi virus entry Identification and biological validation of HPV16 E6/E7-derived T cell target epitopes and their use for performance assessment of MHC class I binding predictors Identification of interleukin1β as an amplifier of interferon alpha-induced antiviral Responses One for all, all for one: Combining and improving AAV, RNAi and CRISPR technologies to combat HBV infection and HBV/HDV co-infections The role of non-canonical NF-kB for liver homeostasis, chronic liver injury and hepatocarcinogenesis Hyperparameter optimization for image analysis: application to prostate tissue images and live cell data of virus-infected cells Towards curative therapy of chronic viral hepatitis GASL 2019 Hepatitis C – von der individuellen Heilung zur weltweiten Elimination? Synthesis, Biological Evaluation, and Molecular Docking of Combretastatin and Colchicine Derivatives and their hCE1‐Activated Prodrugs as Antiviral Agents

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Katalog der Deutschen Nationalbibliothek

Ralf Bartenschlager (1958-)

Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation

Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens

Cell‐Penetrating Peptide‐Bismuth Bicycles **

Cell‐Penetrating Peptide‐Bismuth Bicycles **

A decade after the Nagoya Protocol – German biodiversity researchers’ perspective. Statement of the Permanent Senate Commission on Fundamental Issues of Biological Diversity (SKBV) of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)

Elucidation of the mechanism-of-action of highly potent Dengue virus NS4B inhibitors JNJ-A07 and JNJ-1802

Investigating Fungi- Mammalian Host Interactions in Health and Disease Using Organoids and Mouse Models

Stress Signaling Heterogeneity in Normal and Malignant Hematopoiesis

The Impact of Cycling Hypoxia on the Phenotype of HPV-Positive Cervical Cancer Cells

Virus Venetian Masked Ball: Does the Hepatitis Delta Virus Use Different Helper Viruses?

Zika virus remodelled ER membranes contain proviral factors involved in redox and methylation pathways

SARS-CoV-2 nsp3 and nsp4 are minimal constituents of a pore spanning replication organelle

Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly

Context-specific Roles of Infections and Interferons in Hematopoiesis and Myeloid Neoplasms

Endoplasmic reticulum stress sensor ATF6 as an immunometabolic modulator in hepatic tumorigenesis

Functional and biochemical characterization of viral and host factors involved in the Zika virus replication cycle

Intercellular transmission of viral RNA by Apolipoprotein E-associated extracellular vesicles

Live‐virus neutralization of the omicron variant in children and adults 14 months after SARS‐CoV‐2 wild‐type infection

Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style

Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style

Uncovering a novel role for iron regulatory proteins (IRPs) in adult murine neutropoiesis

Deciphering the molecular regulation of the antiviral deaminase APOBEC3B

Functional and morphological analysis of hepatitis C virus assembly

Functional importance of the lipid kinase phosphatidylinositol 4-kinase III alpha on cytoskeletal organization and its impact on hepatitis C virus-induced liver pathogenesis

HOST FACTORS ASSOCIATED WITH HEPATITIS B VIRUS LIFE-CYCLE: INSIDE AND OUT

Production and characterization of novel BMMF2 rep-specific antibodies and application in cancer histology

Role of LGP2 in the Innate Immune System upon Viral Infections

Temporal control of the integrated stress response by a stochastic molecular switch

The role of tumor suppressor genes PBRM1 and RPS6KA3 in primary liver cancer

A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction

Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2

Interferon‐induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20

SARS‐CoV‐2 infection remodels the host protein thermal stability landscape

Dimer Organization of Membrane‐Associated NS5A of Hepatitis C Virus as Determined by Highly Sensitive 1 H‐Detected Solid‐State NMR

Dysregulated MicroRNAs in Biliary Tract Cancer and Characterization of the Target Tumor Suppressor FHL1

Image analysis in volume SEM datasets

Influence of low oxygen concentrations on barrier function and intrinsic innate immune signaling in the human intestinal mucosa

KDM6A is an epigenetic gatekeeper of mTORC1 signaling in cancer

Role of class III PI3-kinase in double membrane vesicle formation associated with HCV and SARS-CoV-2 replication

SARS-CoV-2 infection remodels the host protein thermal stability landscape

The role of tumor cell-expressed Angiopoietin 2 in malignant melanoma

The SAT Protein of the Minute Virus of Mice Induces the Lysis of the Cell through the Formation of Viroporin-like Structures

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

A Randomized Open label Phase-II Clinical Trial with or without Infusion of Plasma from Subjects after Convalescence of SARS-CoV-2 Infection in High-Risk Patients with Confirmed Severe SARS-CoV-2 Disease (RECOVER): A structured summary of a study protocol for a randomised controlled trial

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

Proton‐Detected Solid‐State NMR of the Cell‐Free Synthesized α‐Helical Transmembrane Protein NS4B from Hepatitis C Virus

A Coupled Mathematical Model of the Intracellular Replication of Dengue Virus and the Host Cell Immune Response to Infection

A SYSTEM TO SEGMENT THE ROLE OF HYALURONIC ACID DURING RE-EPITHELIALIZATION

Deciphering TCR signaling in metabolically activated T-cells in NASH and liver cancer development

Determinants of efficient Hepatitis C Virus RNA replication in cell culture

Early phlebovirus host cell interactions: The small GTPase Rab11 and the autophagic factor Atg7 promote Uukuniemi virus entry

Identification and biological validation of HPV16 E6/E7-derived T cell target epitopes and their use for performance assessment of MHC class I binding predictors

Identification of interleukin1β as an amplifier of interferon alpha-induced antiviral Responses

One for all, all for one: Combining and improving AAV, RNAi and CRISPR technologies to combat HBV infection and HBV/HDV co-infections

The role of non-canonical NF-kB for liver homeostasis, chronic liver injury and hepatocarcinogenesis

Hyperparameter optimization for image analysis: application to prostate tissue images and live cell data of virus-infected cells

Towards curative therapy of chronic viral hepatitis

GASL 2019

Hepatitis C – von der individuellen Heilung zur weltweiten Elimination?

Synthesis, Biological Evaluation, and Molecular Docking of Combretastatin and Colchicine Derivatives and their hCE1‐Activated Prodrugs as Antiviral Agents