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Andreas Trumpp (1964-)

Biologe

Name	Andreas Trumpp
Time	1964- (Date of birth and death)
Place	Heilbronn (Geburtsort) Heidelberg (Wirkungsort) Deutschland
Gender	männlich
Academic degree	Prof. Dr.
Profession	Biologe (characteristic profession)
Related	Heidelberg Institute for Stem Cell Technology and Experimental Medicine Universität Heidelberg. Fakultät für Biowissenschaften (Lehrbeauftragter) (2011-) Deutsches Krebsforschungszentrum
Further information	leitet seit Mitte 2008 die Abteilung Stammzellen und Krebs am Deutschen Krebsforschungszentrum (DKFZ) in Heidelberg, seit 2011 Lehrbeauftragter der Heidelberger Fakultät für Biowissenschaften
Record type	Person
GND-Identifier	1081774134
Record ID	1081774134
Involved in show all Characterization of PARP inhibitor resistance in patient-derived ovarian cancer cell lines Single cell multi-omics and cellular interaction analysis in the healthy and malignant hematopoietic system Unraveling hematopoietic complexity : new insights into murine hematopoietic stem cell heterogeneity and long-term immune alterations in myeloma survivors LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma Analysis of neuronal infiltration in healthy pancreas and pancreatic ductal adenocarcinoma Characterization of the molecular heterogeneity in acute myeloid leukemia for effective targeting of disease-driving leukemic stem cells Classification of acute myeloid leukemia as a ferroptosis-sensitive malignancy suggesting the development of arsenic trioxide mediated ferroptosis-inducing combination therapies High-parametric single-cell readouts for in-depth cellular landscaping and cellular interaction mapping in the immune system Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies Targeting the Leukemic stem cell protein machinery by inhibition of mitochondrial pyrimidine synthesis DNA methylation dynamics of steady state and malignant hematopoiesis Frequent whole blood donations select for DNMT3A variants mediating enhanced response to erythropoietin Molecular and clinical characterization of FOXR2-activated pediatric cancer Multi-omics analysis of DNMT3A- and NPM1-mutated acute myeloid leukemia MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis Regulation of ABCB1 expression is a potential therapeutic target in drug resistant pancreatic cancer SPDEF Regulates Fatty Acid Metabolism Driving Tumor Growth in Androgen Receptor-Positive Breast Cancer Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin Characterization of disseminated breast cancer cells in kidney, pancreas and spleen Hematopoietic stem cells - active modulators of immunity and hematopoiesis in health and disease Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response Myc depletion induces a pluripotent dormant state mimicking diapause SPDEF is a mediator of tumorigenicity in SSEA1- tumor-initiating cells in high grade serous ovarian cancer Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis The role of branched-chain amino acids and BCAT1 in the maintenance of stem cell identity of mouse embryonic stem cells HER2-targeted therapy influences CTC status in metastatic breast cancer Innovations, challenges, and minimal information for standardization of humanized mice Development, Maintenance, and Role of Stem Cell Based Interferon Signaling Heterogeneity in the Hematopoietic System Identification of predictors of patient survival with TSPAN8 as a mediator of tumor aggressiveness in clear cell renal cell carcinoma Single-cell and spatial transcriptomics of the bone marrow The long non-coding RNA Meg3 is dispensable for hematopoietic stem cells Dissecting RNA biology in hematopoietic stem cells: The long non-coding RNA Meg3 is dispensable for hematopoiesis and alternative polyadenylation orchestrates hematopoietic stem cell function Proteomics-based discovery of novel vascular accessible markers in kidney cancer The role of branched chain amino acid catabolism in DNA methylation and acute myeloid leukemia stem cells Sustained prognostic impact of circulating tumor cell status and kinetics upon further progression of metastatic breast cancer Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies Single cell polarity in liquid phase facilitates tumour metastasis JNK signaling in breast cancer cells induces osteopontin and tenascin-C that promote therapy-resistant metastasis Impact of apoptotic circulating tumor cells (aCTC) in metastatic breast cancer Plasma S100P level as a novel prognostic marker of metastatic breast cancer Exploring combined treatment strategies to target quiescent chronic myeloid leukemia (CML) stem cells Identification of a novel enhancer region 1.7 Mb downstream of the c-myc gene controlling its expression in hematopoietic stem and progenitor cells A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition The role of Myc in the ground state of pluripotency Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis Proteomics-based discovery of novel vascular accessible markers in kidney cancer Das limb deformity Gen kodiert neuartige Kernproteine, welche während der embryonalen Determinierung und Differenzierung exprimiert sind

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Katalog der Deutschen Nationalbibliothek

Andreas Trumpp (1964-)

Characterization of PARP inhibitor resistance in patient-derived ovarian cancer cell lines

Single cell multi-omics and cellular interaction analysis in the healthy and malignant hematopoietic system

Unraveling hematopoietic complexity : new insights into murine hematopoietic stem cell heterogeneity and long-term immune alterations in myeloma survivors

LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma

Analysis of neuronal infiltration in healthy pancreas and pancreatic ductal adenocarcinoma

Characterization of the molecular heterogeneity in acute myeloid leukemia for effective targeting of disease-driving leukemic stem cells

Classification of acute myeloid leukemia as a ferroptosis-sensitive malignancy suggesting the development of arsenic trioxide mediated ferroptosis-inducing combination therapies

High-parametric single-cell readouts for in-depth cellular landscaping and cellular interaction mapping in the immune system

Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies

Targeting the Leukemic stem cell protein machinery by inhibition of mitochondrial pyrimidine synthesis

DNA methylation dynamics of steady state and malignant hematopoiesis

Frequent whole blood donations select for DNMT3A variants mediating enhanced response to erythropoietin

Molecular and clinical characterization of FOXR2-activated pediatric cancer

Multi-omics analysis of DNMT3A- and NPM1-mutated acute myeloid leukemia

MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis

Regulation of ABCB1 expression is a potential therapeutic target in drug resistant pancreatic cancer

SPDEF Regulates Fatty Acid Metabolism Driving Tumor Growth in Androgen Receptor-Positive Breast Cancer

Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin

Characterization of disseminated breast cancer cells in kidney, pancreas and spleen

Hematopoietic stem cells - active modulators of immunity and hematopoiesis in health and disease

Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response

Myc depletion induces a pluripotent dormant state mimicking diapause

SPDEF is a mediator of tumorigenicity in SSEA1- tumor-initiating cells in high grade serous ovarian cancer

Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis

The role of branched-chain amino acids and BCAT1 in the maintenance of stem cell identity of mouse embryonic stem cells

HER2-targeted therapy influences CTC status in metastatic breast cancer

Innovations, challenges, and minimal information for standardization of humanized mice

Development, Maintenance, and Role of Stem Cell Based Interferon Signaling Heterogeneity in the Hematopoietic System

Identification of predictors of patient survival with TSPAN8 as a mediator of tumor aggressiveness in clear cell renal cell carcinoma

Single-cell and spatial transcriptomics of the bone marrow

The long non-coding RNA Meg3 is dispensable for hematopoietic stem cells

Dissecting RNA biology in hematopoietic stem cells: The long non-coding RNA Meg3 is dispensable for hematopoiesis and alternative polyadenylation orchestrates hematopoietic stem cell function

Proteomics-based discovery of novel vascular accessible markers in kidney cancer

The role of branched chain amino acid catabolism in DNA methylation and acute myeloid leukemia stem cells

Sustained prognostic impact of circulating tumor cell status and kinetics upon further progression of metastatic breast cancer

Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies

Single cell polarity in liquid phase facilitates tumour metastasis

JNK signaling in breast cancer cells induces osteopontin and tenascin-C that promote therapy-resistant metastasis

Impact of apoptotic circulating tumor cells (aCTC) in metastatic breast cancer

Plasma S100P level as a novel prognostic marker of metastatic breast cancer

Exploring combined treatment strategies to target quiescent chronic myeloid leukemia (CML) stem cells

Identification of a novel enhancer region 1.7 Mb downstream of the c-myc gene controlling its expression in hematopoietic stem and progenitor cells

A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition

The role of Myc in the ground state of pluripotency

Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis

Proteomics-based discovery of novel vascular accessible markers in kidney cancer

Das limb deformity Gen kodiert neuartige Kernproteine, welche während der embryonalen Determinierung und Differenzierung exprimiert sind