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Percy A. Knolle

Arzt

Name	Percy A. Knolle
Place	Heidelberg (Wirkungsort) Deutschland
Academic degree	Prof. Dr. (an der Medizinischen Fakultät der Universität Heidelberg)
Profession	Arzt (characteristic profession)
Variant	Percy Knolle
Further information	Klinikum rechts der Isar
Record type	Person
GND-Identifier	1084650290
Record ID	1084650290
Involved in show all Precursors of exhausted T cells are pre-emptively formed in acute infection Tissue Determinants of Antiviral Immunity in the Liver Immunogenität von SARS-CoV-2 Infektionen und Covid-19 Vakzinen – Ergebnisse prospektiver Kohortenstudien an dem Universitätsklinikum rechts der Isar der Technischen Universität München Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation Attenuated effector T cells are linked to control of chronic HBV infection A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection Attenuated effector T cells are linked to control of chronic HBV infection Cancer-derived Prostaglandin E2 impairs local effector differentiation through attenuation of IL-2 responsiveness in tumor-infiltrating stem-like TCF1+CD8+ T cells Deciphering the Factors Involved in Unresponsiveness to Therapeutic Vaccination Against Chronic Hepatitis B Elucidating the Role of Innate Immunity during Intestinal Inflammation in XIAP deficiency Functional analysis of FSP1 and its novel inhibitors Generation of multicistronic DNA- and mRNA-based therapeutic vaccines against chronic hepatitis B virus infection Prospektive Kohortenstudie zur Erfassung der favorisierten topischen Therapie von Menthol und Polidocanol und Vergleich von deren Wirtschaftlichkeit bei Patienten mit chronischem Pruritus Tumor cell-intrinsic RIG-I signaling regulates anti-tumor T-cell immunity through programmed cell death and extracellular vesicle biogenesis Zelltod und die Entstehung von chronisch entzündlichen Darmerkrankungen = Cell death and the development of chronic inflammatory bowel disease mRNA 3’UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development CD4 T-cell help sustains distinct subpopulations in functional and dysfunctional CD8 T-cell responses. Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+T cells Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling mRNA 3’UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus T cell receptor-dependent protection, recruitment and phenotypes of OVA-specific CD8+ T cells with different avidities in a murine MC38-OVA tumor model The role of cGAS-STING signaling in graft-versus-host disease and intestinal epithelial regeneration Automated detection of neutralizing SARS-CoV-2 antibodies in minutes using a competitive chemiluminescence immunoassay COVID-19-Impfstrategien für Beschäftigte deutscher Kliniken: Ergebnisse einer Befragung von Leitungen der (Krankenhaus‑)Hygiene im Rahmen des B-FAST-Projektes Correction to: Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages Die Regulation der Produktion des Hepatocyte Growth Factor in sinusoidalen Leberendothelzellen IL-6-induced FOXO1 activity determines the dynamics of metabolism in CD8 T cells cross-primed by liver sinusoidal endothelial cells Precision-cut Liver Slices zur Untersuchung zellautonomer antiviraler Abwehr von Hepatozyten ex vivo bei erhaltenen zellulären dreidimensionalen Interaktionen SARS-CoV-2 surveillance and testing: results of a survey from the Network of University Hospitals (NUM), B-FAST Characterization of myeloid cells inducing local T cell activation and proliferation in the hepatic environment Liver-resident CD8+ T cells in resolved and persistent viral infection of the liver Molekulare Mechanismen zur Entstehung des Leberschadens durch CD8+ T-Zellen in nicht-alkoholisch induzierter Fettleber Mucosal-associated invariant T (MAIT) cells are highly activated and functionally impaired in COVID-19 patients NKT cells crosstalk with liver sinusoidal endothelial cells is triggering induction of polyclonal T-cell and NK cell immunity Restoration of HBV-specific CD8+ T cell immunity in chronic HBV infection via a dual mode of action induced by Interferon-signaling SARS-CoV-2 surveillance and testing: results of a survey from the Network of University Hospitals (NUM), B-FAST Dynamik der Antigen-spezifischen CD8 T-Zell-Antwort gegen virale Infektion der Leber Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer Development of cytotoxic mRNAs as new class of anti-cancer biotherapeutics Immunotherapeutic Approaches for the Treatment of Chronic HBV Infection and Hepatocellular Carcinoma Shaping effector and memory T cell differentiation through the immunosuppressive drug leflunomide The transcription factor TOX controls differentiation and maintenance of CD8 T cells in chronic infections The PDL1-inducible GTPase Arl4d controls T effector function by limiting IL-2 production Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity Outcome of antiviral immunity in the liver is shaped by the level of antigen expressed in infected hepatocytes : : hepatology Übertragung des koff-rate-Assays an CD8+ zytotoxischen T-Zellen vom murinen auf das humane System TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation A monoclonal antibody raised against bacterially expressed MPV17 sequences shows peroxisomal, endosomal and lysosomal localisation in U2OS cells The induction of human myeloid derived suppressor cells through hepatic stellate cells is dose-dependently inhibited by the tyrosine kinase inhibitors nilotinib, dasatinib and sorafenib, but not sunitinib Transcriptome‐based profiling of yolk sac‐derived macrophages reveals a role for Irf8 in macrophage maturation Stochastic differentiation of single CD4+ T cells is modulated by T cell receptor avidity IAP antagonization promotes inflammatory destruction of vascular endothelium Differential Induction of Ly6G and Ly6C Positive Myeloid Derived Suppressor Cells in Chronic Kidney and Liver Inflammation and Fibrosis Functional classification of memory CD8+ T cells by CX3CR1 expression

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Katalog der Deutschen Nationalbibliothek

Percy A. Knolle

Precursors of exhausted T cells are pre-emptively formed in acute infection

Tissue Determinants of Antiviral Immunity in the Liver

Immunogenität von SARS-CoV-2 Infektionen und Covid-19 Vakzinen – Ergebnisse prospektiver Kohortenstudien an dem Universitätsklinikum rechts der Isar der Technischen Universität München

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation

Attenuated effector T cells are linked to control of chronic HBV infection

A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection

Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics

PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells

A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection

Attenuated effector T cells are linked to control of chronic HBV infection

Cancer-derived Prostaglandin E2 impairs local effector differentiation through attenuation of IL-2 responsiveness in tumor-infiltrating stem-like TCF1+CD8+ T cells

Deciphering the Factors Involved in Unresponsiveness to Therapeutic Vaccination Against Chronic Hepatitis B

Elucidating the Role of Innate Immunity during Intestinal Inflammation in XIAP deficiency

Functional analysis of FSP1 and its novel inhibitors

Generation of multicistronic DNA- and mRNA-based therapeutic vaccines against chronic hepatitis B virus infection

Prospektive Kohortenstudie zur Erfassung der favorisierten topischen Therapie von Menthol und Polidocanol und Vergleich von deren Wirtschaftlichkeit bei Patienten mit chronischem Pruritus

Tumor cell-intrinsic RIG-I signaling regulates anti-tumor T-cell immunity through programmed cell death and extracellular vesicle biogenesis

Zelltod und die Entstehung von chronisch entzündlichen Darmerkrankungen = Cell death and the development of chronic inflammatory bowel disease

mRNA 3’UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus

Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development

CD4 T-cell help sustains distinct subpopulations in functional and dysfunctional CD8 T-cell responses.

Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+T cells

Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

mRNA 3’UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus

T cell receptor-dependent protection, recruitment and phenotypes of OVA-specific CD8+ T cells with different avidities in a murine MC38-OVA tumor model

The role of cGAS-STING signaling in graft-versus-host disease and intestinal epithelial regeneration

Automated detection of neutralizing SARS-CoV-2 antibodies in minutes using a competitive chemiluminescence immunoassay

COVID-19-Impfstrategien für Beschäftigte deutscher Kliniken: Ergebnisse einer Befragung von Leitungen der (Krankenhaus‑)Hygiene im Rahmen des B-FAST-Projektes

Correction to: Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages

Die Regulation der Produktion des Hepatocyte Growth Factor in sinusoidalen Leberendothelzellen

IL-6-induced FOXO1 activity determines the dynamics of metabolism in CD8 T cells cross-primed by liver sinusoidal endothelial cells

Precision-cut Liver Slices zur Untersuchung zellautonomer antiviraler Abwehr von Hepatozyten ex vivo bei erhaltenen zellulären dreidimensionalen Interaktionen

SARS-CoV-2 surveillance and testing: results of a survey from the Network of University Hospitals (NUM), B-FAST

Characterization of myeloid cells inducing local T cell activation and proliferation in the hepatic environment

Liver-resident CD8+ T cells in resolved and persistent viral infection of the liver

Molekulare Mechanismen zur Entstehung des Leberschadens durch CD8+ T-Zellen in nicht-alkoholisch induzierter Fettleber

Mucosal-associated invariant T (MAIT) cells are highly activated and functionally impaired in COVID-19 patients

NKT cells crosstalk with liver sinusoidal endothelial cells is triggering induction of polyclonal T-cell and NK cell immunity

Restoration of HBV-specific CD8+ T cell immunity in chronic HBV infection via a dual mode of action induced by Interferon-signaling

SARS-CoV-2 surveillance and testing: results of a survey from the Network of University Hospitals (NUM), B-FAST

Dynamik der Antigen-spezifischen CD8 T-Zell-Antwort gegen virale Infektion der Leber

Single organelle analysis to characterize mitochondrial function and crosstalk during viral infection

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Development of cytotoxic mRNAs as new class of anti-cancer biotherapeutics

Immunotherapeutic Approaches for the Treatment of Chronic HBV Infection and Hepatocellular Carcinoma

Shaping effector and memory T cell differentiation through the immunosuppressive drug leflunomide

The transcription factor TOX controls differentiation and maintenance of CD8 T cells in chronic infections

The PDL1-inducible GTPase Arl4d controls T effector function by limiting IL-2 production

Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity

Outcome of antiviral immunity in the liver is shaped by the level of antigen expressed in infected hepatocytes : : hepatology

Übertragung des koff-rate-Assays an CD8+ zytotoxischen T-Zellen vom murinen auf das humane System

TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation

A monoclonal antibody raised against bacterially expressed MPV17 sequences shows peroxisomal, endosomal and lysosomal localisation in U2OS cells

The induction of human myeloid derived suppressor cells through hepatic stellate cells is dose-dependently inhibited by the tyrosine kinase inhibitors nilotinib, dasatinib and sorafenib, but not sunitinib

Transcriptome‐based profiling of yolk sac‐derived macrophages reveals a role for Irf8 in macrophage maturation

Stochastic differentiation of single CD4+ T cells is modulated by T cell receptor avidity

IAP antagonization promotes inflammatory destruction of vascular endothelium

Differential Induction of Ly6G and Ly6C Positive Myeloid Derived Suppressor Cells in Chronic Kidney and Liver Inflammation and Fibrosis

Functional classification of memory CD8+ T cells by CX3CR1 expression