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Mike Heilemann

Name	Mike Heilemann
Place	Heidelberg (Wirkungsort) Deutschland
Academic degree	Prof. Dr.
Related	BioQuant
Further information	Principal Investigator Goethe-Universität Frankfurt, Institute of Physical and Theoretical Chemistry, Germany
Record type	Person
GND-Identifier	1096549891
Record ID	1096549891
Involved in show all Long‐Term Single‐Molecule Tracking in Living Cells using Weak‐Affinity Protein Labeling Long‐Term Single‐Molecule Tracking in Living Cells using Weak‐Affinity Protein Labeling Fast and Long‐Term Super‐Resolution Imaging of Endoplasmic Reticulum Nano‐structural Dynamics in Living Cells Using a Neural Network This Microtubule Does Not Exist: Super‐Resolution Microscopy Image Generation by a Diffusion Model Channelrhodopsin‐2 Oligomerization in Cell Membrane Revealed by Photo‐Activated Localization Microscopy Channelrhodopsin‐2 Oligomerization in Cell Membrane Revealed by Photo‐Activated Localization Microscopy Exploring the application of deep learning for super-resolution microscopy Fast and long-term super-resolution imaging of ER nano-structural dynamics in living cells using a neural network The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways Self‐quenched Fluorophore Dimers for DNA‐PAINT and STED Microscopy Self‐quenched Fluorophore Dimers for DNA‐PAINT and STED Microscopy When Weak Is Strong: A Plea for Low‐Affinity Binders for Optical Microscopy When Weak Is Strong: A Plea for Low‐Affinity Binders for Optical Microscopy Biased activation of the receptor tyrosine kinase HER2 Biased activation of the receptor tyrosine kinase HER2 Biased activation of the receptor tyrosine kinase HER2 Single-molecule FRET and molecular dynamics simulations reveal early activation steps of MET receptor by Listeria monocytogenes The molecular architecture of the kidney slit diaphragm The molecular architecture of the kidney slit diaphragm Fast DNA-PAINT imaging using a deep neural network Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches Biased activation of the receptor tyrosine kinase HER2 Cyclophilin anaCyp40 regulates photosystem assembly and phycobilisome association in a cyanobacterium Dynamic in situ confinement triggers ligand-free neuropeptide receptor signaling Dynamic in situ confinement triggers ligand-free neuropeptide receptor signaling Fast DNA-PAINT imaging using a deep neural network Receptor tyrosine kinase MET ligand-interaction classified via machine learning from single-particle tracking data Multi‐Color, Bleaching‐Resistant Super‐Resolution Optical Fluctuation Imaging with Oligonucleotide‐Based Exchangeable Fluorophores Multi‐Color, Bleaching‐Resistant Super‐Resolution Optical Fluctuation Imaging with Oligonucleotide‐Based Exchangeable Fluorophores Diffusion state transitions in single-particle trajectories of MET receptor tyrosine kinase measured in live cells Fast DNA-PAINT imaging using a deep neural network KAHRP dynamically relocalizes to remodeled actin junctions and associates with knob spirals in Plasmodium falciparum-infected erythrocytes KAHRP dynamically relocalizes to remodeled actin junctions and associates with knob spirals in Plasmodium falciparum-infected erythrocytes Quantitative single‐molecule imaging of TNFR1 reveals zafirlukast as antagonist of TNFR1 clustering and TNFα‐induced NF‐ĸB signaling Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection Switching at the ribosome: riboswitches need rProteins as modulators to regulate translation The prevalence and specificity of local protein synthesis during neuronal synaptic plasticity Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53 Visualizing multi-protein patterns at the synapse of neuronal tissue with DNA-assisted single-molecule localization microscopy Visualizing synaptic multi-protein patterns of neuronal tissue with DNA-assisted single-molecule localization microscopy Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia Automated highly multiplexed super-resolution imaging of protein nano-architecture in cells and tissues CRISPR/Cas12a-mediated labeling of MET receptor enables quantitative single-molecule imaging of endogenous protein organization and dynamics Multi-color, bleaching-resistant super-resolution optical fluctuation imaging with oligonucleotide-based exchangeable fluorophores Single-molecule super-resolution microscopy reveals heteromeric complexes of MET and EGFR upon ligand activation Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia Single-molecule imaging and quantification of the immune-variant adhesin VAR2CSA on knobs of Plasmodium falciparum-infected erythrocytes Visualizing ubiquitination in mammalian cells Protein‐Specific, Multicolor and 3D STED Imaging in Cells with DNA‐Labeled Antibodies Automated highly multiplexed super-resolution imaging of protein nano-architecture in cells and tissues Protein-specific, multicolor and 3D STED imaging in cells with DNA-labeled antibodies Single-molecule imaging and quantification of the immune-variant adhesin VAR2CSA on knobs of Plasmodium falciparum-infected erythrocytes A toolbox for multiplexed super-resolution imaging of the E. coli nucleoid and membrane using novel PAINT labels Enhanced labeling density and whole-cell 3D dSTORM imaging by repetitive labeling of target proteins Super‐Chelators for Advanced Protein Labeling in Living Cells Super‐Chelators for Advanced Protein Labeling in Living Cells Frontispiece: Super‐Chelators for Advanced Protein Labeling in Living Cells A toolbox for multiplexed super-resolution imaging of the E. coli nucleoid and membrane using novel PAINT labels

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Mike Heilemann

Long‐Term Single‐Molecule Tracking in Living Cells using Weak‐Affinity Protein Labeling

Long‐Term Single‐Molecule Tracking in Living Cells using Weak‐Affinity Protein Labeling

Fast and Long‐Term Super‐Resolution Imaging of Endoplasmic Reticulum Nano‐structural Dynamics in Living Cells Using a Neural Network

This Microtubule Does Not Exist: Super‐Resolution Microscopy Image Generation by a Diffusion Model

Channelrhodopsin‐2 Oligomerization in Cell Membrane Revealed by Photo‐Activated Localization Microscopy

Channelrhodopsin‐2 Oligomerization in Cell Membrane Revealed by Photo‐Activated Localization Microscopy

Exploring the application of deep learning for super-resolution microscopy

Fast and long-term super-resolution imaging of ER nano-structural dynamics in living cells using a neural network

The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways

Self‐quenched Fluorophore Dimers for DNA‐PAINT and STED Microscopy

Self‐quenched Fluorophore Dimers for DNA‐PAINT and STED Microscopy

When Weak Is Strong: A Plea for Low‐Affinity Binders for Optical Microscopy

When Weak Is Strong: A Plea for Low‐Affinity Binders for Optical Microscopy

Biased activation of the receptor tyrosine kinase HER2

Biased activation of the receptor tyrosine kinase HER2

Biased activation of the receptor tyrosine kinase HER2

Single-molecule FRET and molecular dynamics simulations reveal early activation steps of MET receptor by Listeria monocytogenes

The molecular architecture of the kidney slit diaphragm

The molecular architecture of the kidney slit diaphragm

Fast DNA-PAINT imaging using a deep neural network

Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells

DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches

Biased activation of the receptor tyrosine kinase HER2

Cyclophilin anaCyp40 regulates photosystem assembly and phycobilisome association in a cyanobacterium

Dynamic in situ confinement triggers ligand-free neuropeptide receptor signaling

Dynamic in situ confinement triggers ligand-free neuropeptide receptor signaling

Fast DNA-PAINT imaging using a deep neural network

Receptor tyrosine kinase MET ligand-interaction classified via machine learning from single-particle tracking data

Multi‐Color, Bleaching‐Resistant Super‐Resolution Optical Fluctuation Imaging with Oligonucleotide‐Based Exchangeable Fluorophores

Multi‐Color, Bleaching‐Resistant Super‐Resolution Optical Fluctuation Imaging with Oligonucleotide‐Based Exchangeable Fluorophores

Diffusion state transitions in single-particle trajectories of MET receptor tyrosine kinase measured in live cells

Fast DNA-PAINT imaging using a deep neural network

KAHRP dynamically relocalizes to remodeled actin junctions and associates with knob spirals in Plasmodium falciparum-infected erythrocytes

KAHRP dynamically relocalizes to remodeled actin junctions and associates with knob spirals in Plasmodium falciparum-infected erythrocytes

Quantitative single‐molecule imaging of TNFR1 reveals zafirlukast as antagonist of TNFR1 clustering and TNFα‐induced NF‐ĸB signaling

Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection

Switching at the ribosome: riboswitches need rProteins as modulators to regulate translation

The prevalence and specificity of local protein synthesis during neuronal synaptic plasticity

Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53

Visualizing multi-protein patterns at the synapse of neuronal tissue with DNA-assisted single-molecule localization microscopy

Visualizing synaptic multi-protein patterns of neuronal tissue with DNA-assisted single-molecule localization microscopy

Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors

Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia

Automated highly multiplexed super-resolution imaging of protein nano-architecture in cells and tissues

CRISPR/Cas12a-mediated labeling of MET receptor enables quantitative single-molecule imaging of endogenous protein organization and dynamics

Multi-color, bleaching-resistant super-resolution optical fluctuation imaging with oligonucleotide-based exchangeable fluorophores

Single-molecule super-resolution microscopy reveals heteromeric complexes of MET and EGFR upon ligand activation

Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia

Single-molecule imaging and quantification of the immune-variant adhesin VAR2CSA on knobs of Plasmodium falciparum-infected erythrocytes

Visualizing ubiquitination in mammalian cells

Protein‐Specific, Multicolor and 3D STED Imaging in Cells with DNA‐Labeled Antibodies

Automated highly multiplexed super-resolution imaging of protein nano-architecture in cells and tissues

Protein-specific, multicolor and 3D STED imaging in cells with DNA-labeled antibodies

Single-molecule imaging and quantification of the immune-variant adhesin VAR2CSA on knobs of Plasmodium falciparum-infected erythrocytes

A toolbox for multiplexed super-resolution imaging of the E. coli nucleoid and membrane using novel PAINT labels

Enhanced labeling density and whole-cell 3D dSTORM imaging by repetitive labeling of target proteins

Super‐Chelators for Advanced Protein Labeling in Living Cells

Super‐Chelators for Advanced Protein Labeling in Living Cells

Frontispiece: Super‐Chelators for Advanced Protein Labeling in Living Cells

A toolbox for multiplexed super-resolution imaging of the E. coli nucleoid and membrane using novel PAINT labels