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Burkhart Schraven

Name	Burkhart Schraven
Place	Heidelberg (Wirkungsort) Deutschland
Academic degree	Prof. Dr.
Variant	Burkhart L. Schraven
Further information	Nov. 1995 - March 2001 Head of the Immunomodulation Laboratory of the Institute for Immunology, University of Heidelberg; Institut für Molekulare und Klinische Immunologie, Otto-von-Guericke-Universität Magdeburg
Record type	Person
GND-Identifier	1108307582
Record ID	1108307582
Involved in show all Neutrophil-specific expression of JAK2-V617F or CALRmut induces distinct inflammatory profiles in myeloproliferative neoplasia Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry Combined immunodeficiency caused by a novel nonsense mutation in LCK Combined Immunodeficiency Caused by a Novel Nonsense Mutation in LCK Plasma concentrations of anti-inflammatory cytokine TGF-β are associated with hippocampal structure related to explicit memory performance in older adults Allgemeine Kenntnisse zu häufig angewandten Testverfahren in der rheumatologisch-immunologischen Diagnostik und Forschung A cysteine residue within the kinase domain of Zap70 regulates Lck activity and proximal TCR signaling IL-13 determines specific IgE responses and SARS-CoV-2 immunity after mild COVID-19 and novel mRNA vaccination T cell-specific constitutive active SHP2 enhances T cell memory formation and reduces T cell activation T cell-specific constitutive active SHP2 enhances T cell memory formation and reduces T cell activation Cooperative interaction of Nck and Lck orchestrates optimal TCR signaling The Multiple Roles of the Cytosolic Adapter Proteins ADAP, SKAP1 and SKAP2 for TCR/CD3 -Mediated Signaling Events Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions Charakterisierung von Test-Granulozyten zum Nachweis Granulozyten-reaktiver Antikörper für die Prävention der TRALI mit einer neu entwickelten Multiplex-PCR Methode und Analyse der HNA-Allelfrequenzen in Sachsen-Anhalt Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions Longitudinal proliferation mapping in vivo reveals NADPH oxidase-mediated dampening of Staphylococcus aureus growth rates within neutrophils Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling Influence of the JAK2-V617F mutation on integrin-mediated adhesion to VCAM1 in murine and human cell lines in the context of classical Philadelphia-negative myeloproliferative neoplasms Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling Early changes in the metabolic profile of activated CD8+ T cells Mathematical modeling and evolution of signal transduction pathways and networks Molecular alterations of the Fyn‐complex occur as late events of human T cell activation Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2‐interacting transmembrane adaptor protein) Etablierung von In-vitro-Systemen zur Analyse der Interaktion zwischen B-Zellen und T-Zellen

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Burkhart Schraven

Neutrophil-specific expression of JAK2-V617F or CALRmut induces distinct inflammatory profiles in myeloproliferative neoplasia

Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry

Combined immunodeficiency caused by a novel nonsense mutation in LCK

Combined Immunodeficiency Caused by a Novel Nonsense Mutation in LCK

Plasma concentrations of anti-inflammatory cytokine TGF-β are associated with hippocampal structure related to explicit memory performance in older adults

Allgemeine Kenntnisse zu häufig angewandten Testverfahren in der rheumatologisch-immunologischen Diagnostik und Forschung

A cysteine residue within the kinase domain of Zap70 regulates Lck activity and proximal TCR signaling

IL-13 determines specific IgE responses and SARS-CoV-2 immunity after mild COVID-19 and novel mRNA vaccination

T cell-specific constitutive active SHP2 enhances T cell memory formation and reduces T cell activation

T cell-specific constitutive active SHP2 enhances T cell memory formation and reduces T cell activation

Cooperative interaction of Nck and Lck orchestrates optimal TCR signaling

The Multiple Roles of the Cytosolic Adapter Proteins ADAP, SKAP1 and SKAP2 for TCR/CD3 -Mediated Signaling Events

Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions

Charakterisierung von Test-Granulozyten zum Nachweis Granulozyten-reaktiver Antikörper für die Prävention der TRALI mit einer neu entwickelten Multiplex-PCR Methode und Analyse der HNA-Allelfrequenzen in Sachsen-Anhalt

Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions

Longitudinal proliferation mapping in vivo reveals NADPH oxidase-mediated dampening of Staphylococcus aureus growth rates within neutrophils

Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling

Influence of the JAK2-V617F mutation on integrin-mediated adhesion to VCAM1 in murine and human cell lines in the context of classical Philadelphia-negative myeloproliferative neoplasms

Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling

Early changes in the metabolic profile of activated CD8+ T cells

Mathematical modeling and evolution of signal transduction pathways and networks

Molecular alterations of the Fyn‐complex occur as late events of human T cell activation

Structural and functional dissection of the cytoplasmic domain of the transmembrane adaptor protein SIT (SHP2‐interacting transmembrane adaptor protein)

Etablierung von In-vitro-Systemen zur Analyse der Interaktion zwischen B-Zellen und T-Zellen