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Hanspeter Pircher (1953-)

Biochemiker

Name	Hanspeter Pircher
Time	1953- (Date of birth and death)
Place	Zürich (Geburtsort) Deutschland
Academic degree	Prof. Dr.
Profession	Biochemiker (characteristic profession)
Related	Institut für Immunologie (Freiburg im Breisgau)
Further information	Direktor des Instituts für Immunologie, Universitätsklinikum Freiburg
Record type	Person
GND-Identifier	1110800584
Record ID	1110800584
Involved in show all Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect MHC I tetramer staining tends to overestimate the number of functionally relevant self‐reactive CD8 T cells in the preimmune repertoire MHC I tetramer staining tends to overestimate the number of functionally relevant self‐reactive CD8 T cells in the preimmune repertoire Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors NK1.1 + innate lymphoid cells in salivary glands inhibit establishment of tissue‐resident memory CD8 + T cells in mice Trigger‐dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis NK1.1 + innate lymphoid cells in salivary glands inhibit establishment of tissue‐resident memory CD8 + T cells in mice Trigger‐dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis Enhancing immunity prevents virus‐induced T‐cell‐mediated immunopathology in B cell‐deficient mice Expression of IL‐7Rα and KLRG1 defines functionally distinct CD8 + T‐cell populations in humans Residual LCMV antigen in transiently CD4 + T cell‐depleted mice induces high levels of virus‐specific antibodies but only limited B‐cell memory Enhancing immunity prevents virus‐induced T‐cell‐mediated immunopathology in B cell‐deficient mice Expression of IL‐7R[alpha] and KLRG1 defines functionally distinct CD8+ T-cell populations in humans Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells Immunological tolerance to LCMV antigens differently affects control of acute and chronic virus infection in mice Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells Regulation of tissue-resident memory CD8+ T cells in salivary glands CMV drives the expansion of highly functional memory T cells expressing NK‐cell receptors in renal transplant recipients TGF‐β downregulates KLRG1 expression in mouse and human CD8 + T cells KLRG 1 activity is regulated by association with the transferrin receptor Expanded human blood-derived [gamma] [delta] T cells display potent antigen-presentation functions Nucleoprotein‐specific nonneutralizing antibodies speed up LCMV elimination independently of complement and F cγ R Inhibitory receptor expression depends more dominantly on differentiation and activation than “exhaustion” of human CD8 T cells Different inhibitory capacities of human and mouse KLRG1 are linked to distinct disulfide‐mediated oligomerizations The NK receptor KLRG1 is dispensable for virus‐induced NK and CD8 + T‐cell differentiation and function in vivo Interaction of KLRG1 with E‐cadherin: New functional and structural insights Efficacy of IL‐2‐ versus IL‐15‐stimulated CD8 T cells in adoptive immunotherapy Generation and characterization of cloned hapten-specific cyto-toxic T-lymphocytes

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Hanspeter Pircher (1953-)

Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect

MHC I tetramer staining tends to overestimate the number of functionally relevant self‐reactive CD8 T cells in the preimmune repertoire

MHC I tetramer staining tends to overestimate the number of functionally relevant self‐reactive CD8 T cells in the preimmune repertoire

Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors

NK1.1 + innate lymphoid cells in salivary glands inhibit establishment of tissue‐resident memory CD8 + T cells in mice

Trigger‐dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis

NK1.1 + innate lymphoid cells in salivary glands inhibit establishment of tissue‐resident memory CD8 + T cells in mice

Trigger‐dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis

Enhancing immunity prevents virus‐induced T‐cell‐mediated immunopathology in B cell‐deficient mice

Expression of IL‐7Rα and KLRG1 defines functionally distinct CD8 + T‐cell populations in humans

Residual LCMV antigen in transiently CD4 + T cell‐depleted mice induces high levels of virus‐specific antibodies but only limited B‐cell memory

Enhancing immunity prevents virus‐induced T‐cell‐mediated immunopathology in B cell‐deficient mice

Expression of IL‐7R[alpha] and KLRG1 defines functionally distinct CD8+ T-cell populations in humans

Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells

Immunological tolerance to LCMV antigens differently affects control of acute and chronic virus infection in mice

Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells

Regulation of tissue-resident memory CD8+ T cells in salivary glands

CMV drives the expansion of highly functional memory T cells expressing NK‐cell receptors in renal transplant recipients

TGF‐β downregulates KLRG1 expression in mouse and human CD8 + T cells

KLRG 1 activity is regulated by association with the transferrin receptor

Expanded human blood-derived [gamma] [delta] T cells display potent antigen-presentation functions

Nucleoprotein‐specific nonneutralizing antibodies speed up LCMV elimination independently of complement and F cγ R

Inhibitory receptor expression depends more dominantly on differentiation and activation than “exhaustion” of human CD8 T cells

Different inhibitory capacities of human and mouse KLRG1 are linked to distinct disulfide‐mediated oligomerizations

The NK receptor KLRG1 is dispensable for virus‐induced NK and CD8 + T‐cell differentiation and function in vivo

Interaction of KLRG1 with E‐cadherin: New functional and structural insights

Efficacy of IL‐2‐ versus IL‐15‐stimulated CD8 T cells in adoptive immunotherapy

Generation and characterization of cloned hapten-specific cyto-toxic T-lymphocytes