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René Csuk

Chemiker

Name	René Csuk
Place	Halle (Saale) (Wirkungsort) Wittenberg (Wirkungsort) Deutschland
Academic degree	Prof. Dr.
Profession	Chemiker (characteristic profession)
Related	Martin-Luther-Universität Halle-Wittenberg. Institut für Chemie (1995) Universität Heidelberg. Institut für Pharmazie und Molekulare Biotechnologie (1989-1995)
Further information	ab 09/1989: wissenschaftl. Assistent (Pharmazeutisch-Chemisches Inst., Univ. Heidelberg) (Prof. Dr. R. Neidlein); 04/1992: Habilitation für das Fach "Pharmazeutische Chemie" an der Univ. Heidelberg; 10/92-09/95: Vertretung der Professur "Pharmazeutische Chemie" (C3) an der Fakultät f. Pharmazie, Univ. Heidelberg; seit 10/1995: Professur C4 für Organische Chemie an der Martin-Luther-Universität Halle-Wittenberg, Geschäftsführender Institutsdirektor
Record type	Person
GND-Identifier	1153927675
Record ID	1153927675
Involved in show all Advancing Anticancer Drug Discovery: Leveraging Metabolomics and Machine Learning for Mode of Action Prediction by Pattern Recognition Identification of new pharmacophore against SARS-CoV-2 spike protein by multi-fold computational and biochemical techniques Elongation of Very Long-Chain Fatty Acids (ELOVL) in Atopic Dermatitis and the Cutaneous Adverse Effect AGEP of Drugs Weed control by biological compounds identified in necrotizing plant pathogenic fungi Acetylcholinesterase Inhibitory Activity of Modified Lupane, Oleanane, and Ursane A‐ seco ‐Triterpenoids α-Glucosidase and cholinesterase inhibiting potential of a series of semisynthetic nitrogen triterpenic derivatives Converting bile acids into mitocans Mirror-symmetry breaking in photoswitchable liquid crystalline materials Synthese antitumoraktiver Triterpen-Carbonsäure-Derivate und deren biologische Evaluierung Synthese und Biokompatibilitätsbewertungen neuartiger, biofunktioneller Polymere für die Medizintechnik Synthese und biologische Evaluierung von Naturstoffderivaten Synthese und biologische Evaluierung von Naturstoffderivaten Synthese, Charakterisierung und biologische Evaluierung von Triterpencarbonsäure- und Naturstoffderivaten Comparative study of the cytotoxicity, apoptotic, and epigenetic effects of Boswellic acid derivatives on breast cancer Synthesis and Exploitation of the Biological Profile of Novel Guanidino Xylofuranose Derivatives ** Platanic acid derived amides are more cytotoxic than their corresponding oximes A fluorescence-based competitive antibody binding assay for kynurenine, a potential biomarker of kidney transplant failure Betulinic acid and glycyrrhetinic acid derived piperazinyl spacered rhodamine B conjugates are highly cytotoxic and necrotic Betulinsulfonamide als Prodrug gegen hypoxische Tumoren Hydroxyethylamide substituted triterpenoic acids hold good cytotoxicity for human tumor cells Synthese und Charakterisierung neuartiger Hemmstoffe der mykobakteriellen DNA Gyrase Synthesis of a biocompatible benzophenone-substituted chitosan hydrogel as novel coating for PEEK with extraordinary strong antibacterial and anti-biofilm properties Drug triggered pruritus, rash, papules, and blisters – is AGEP a clash of an altered sphingolipid-metabolism and lysosomotropism of drugs accumulating in the skin? Racemization-free synthesis of Nα-2-thiophenoyl-phenylalanine-2-morpholinoanilide enantiomers and their antimycobacterial activity New synthetic 1H-1,2,3-triazole derivatives of 3-O-acetyl-β-boswellic acid and 3-O-acetyl-11-keto-β-boswellic acid from Boswellia sacra inhibit carbonic anhydrase II in vitro n-Propyl 6-amino-2,6-dideoxy-2,2-difluoro-β-d-glucopyranoside is a good inhibitor for the β-galactosidase from E. coli New amino acid clubbed Schiff bases inhibit carbonic anhydrase II, α-glucosidase, and urease enzymes: in silico and in vitro Antibacterial and Cytotoxic Activity of Ruthenium‐ p ‐cymene Complexes with 2‐Methylquinolin‐8‐ol Derivatives Apoptotic activity of substituted 3-O-acetyl-betulinic acid benzylamides Design, synthesis and biological evaluation of novel pyrazolo[1,2,4]triazolopyrimidine derivatives as potential anticancer agents Design, Synthesis and Biological Evaluation of Novel Pyrazolo[1,2,4]triazolopyrimidine Derivatives as Potential Anticancer Agents Drugs, metabolites, and lung accumulating small lysosomotropic molecules: multiple targeting impedes SARS-CoV-2 infection and progress to COVID-19 Lineage-selective disturbance of early human hematopoietic progenitor cell differentiation by the commonly used plasticizer Di-2-ethylhexyl phthalate via reactive oxygen species: fatty acid oxidation makes the difference Lineage-Selective Disturbance of Early Human Hematopoietic Progenitor Cell Differentiation by the Commonly Used Plasticizer Di-2-ethylhexyl Phthalate via Reactive Oxygen Species: Fatty Acid Oxidation Makes the Difference Methacryloyl-GlcNAc Derivatives Copolymerized with Dimethacrylamide as a Novel Antibacterial and Biocompatible Coating n-Propyl 6-amino-2,6-dideoxy-2,2-difluoro-β-D-glucopyranoside is a good inhibitor for the β-galactosidase from E. coli Synthese und biologische Evaluierung von Naturstoffderivaten : [kumulative Dissertation] Synthesis and structure of azelastine-N-oxides The Presence of a Cyclohexyldiamine Moiety Confers Cytotoxicity to Pentacyclic Triterpenoids Ester and amide derivatives of rhodamine B exert cytotoxic effects on different human tumor cell lines Evaluation of cholinesterase inhibitory activity and cytotoxicity of synthetic derivatives of di- and triterpene metabolites from Pinus silvestris and Dipterocarpus alatus resins Synthesis and cytotoxic evaluation of malachite green derived oleanolic and ursolic acid piperazineamides Identification and quantification of cannabinol as a biomarker for local hemp retting in an ancient sedimentary record by HPTLC-ESI-MS Total Synthesis of Surinamensinols A and B Squaramide–Quaternary Ammonium Salt as an Effective Binary Organocatalytic System for Oxazolidinone Synthesis from Isocyanates and Epoxides COVID-19/SARS-CoV-2 Infection: Lysosomes and Lysosomotropism Implicate New Treatment Strategies and Personal Risks Metabolite Patterns in Human Myeloid Hematopoiesis Result from Lineage-Dependent Active Metabolic Pathways Rational drug repurposing: focus on lysosomotropism, targets in disease process, drug profile, and pulmonary tissue accumulation in SARS-CoV-2 Infection/COVID-19 Rational Drug Repurposing: Focus on Lysosomotropism, Targets in Disease Process, Drug Profile, and Pulmonary Tissue Accumulation in SARS-CoV-2 Infection/COVID-19 Synthese und biologische Evaluierung von aromatischen Pflanzeninhaltsstoffen Synthese und biologische Evaluierung von Zimtsäure-Derivaten Mapping Natural Dyes in Archeological Textiles by Imaging Mass Spectrometry Synthese antitumoraktiver Triterpen-Carbonsäure-Derivate : [kumulative Dissertation] Synthese und biologische Evaluierung von Naturstoffanaloga hinsichtlich ihrer Inhibierung von Cholinesterasen Synthese von Triterpenderivaten und ihre biologische Evaluierung : [kumulative Dissertation] Platanic acid-derived methyl 20-amino-30-norlupan-28-oates are potent cytotoxic agents acting by apoptosis Furanosyl Nucleoside Analogues Embodying Triazole or Theobromine Units as Potential Lead Molecules for Alzheimer's Disease Drotaverine – a Concealed Cytostatic! Synthesis of glucopyranos-6′-yl purine and pyrimidine isonucleosides as potential cholinesterase inhibitors. Access to pyrimidine-linked pseudodisaccharides through Mitsunobu reaction Synthesis and Evaluation of the Biological Profile of Novel Analogues of Nucleosides and of Potential Mimetics of Sugar Phosphates and Nucleotides

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Katalog der Deutschen Nationalbibliothek

René Csuk

Advancing Anticancer Drug Discovery: Leveraging Metabolomics and Machine Learning for Mode of Action Prediction by Pattern Recognition

Identification of new pharmacophore against SARS-CoV-2 spike protein by multi-fold computational and biochemical techniques

Elongation of Very Long-Chain Fatty Acids (ELOVL) in Atopic Dermatitis and the Cutaneous Adverse Effect AGEP of Drugs

Weed control by biological compounds identified in necrotizing plant pathogenic fungi

Acetylcholinesterase Inhibitory Activity of Modified Lupane, Oleanane, and Ursane A‐ seco ‐Triterpenoids

α-Glucosidase and cholinesterase inhibiting potential of a series of semisynthetic nitrogen triterpenic derivatives

Converting bile acids into mitocans

Mirror-symmetry breaking in photoswitchable liquid crystalline materials

Synthese antitumoraktiver Triterpen-Carbonsäure-Derivate und deren biologische Evaluierung

Synthese und Biokompatibilitätsbewertungen neuartiger, biofunktioneller Polymere für die Medizintechnik

Synthese und biologische Evaluierung von Naturstoffderivaten

Synthese und biologische Evaluierung von Naturstoffderivaten

Synthese, Charakterisierung und biologische Evaluierung von Triterpencarbonsäure- und Naturstoffderivaten

Comparative study of the cytotoxicity, apoptotic, and epigenetic effects of Boswellic acid derivatives on breast cancer

Synthesis and Exploitation of the Biological Profile of Novel Guanidino Xylofuranose Derivatives **

Platanic acid derived amides are more cytotoxic than their corresponding oximes

A fluorescence-based competitive antibody binding assay for kynurenine, a potential biomarker of kidney transplant failure

Betulinic acid and glycyrrhetinic acid derived piperazinyl spacered rhodamine B conjugates are highly cytotoxic and necrotic

Betulinsulfonamide als Prodrug gegen hypoxische Tumoren

Hydroxyethylamide substituted triterpenoic acids hold good cytotoxicity for human tumor cells

Synthese und Charakterisierung neuartiger Hemmstoffe der mykobakteriellen DNA Gyrase

Synthesis of a biocompatible benzophenone-substituted chitosan hydrogel as novel coating for PEEK with extraordinary strong antibacterial and anti-biofilm properties

Drug triggered pruritus, rash, papules, and blisters – is AGEP a clash of an altered sphingolipid-metabolism and lysosomotropism of drugs accumulating in the skin?

Racemization-free synthesis of Nα-2-thiophenoyl-phenylalanine-2-morpholinoanilide enantiomers and their antimycobacterial activity

New synthetic 1H-1,2,3-triazole derivatives of 3-O-acetyl-β-boswellic acid and 3-O-acetyl-11-keto-β-boswellic acid from Boswellia sacra inhibit carbonic anhydrase II in vitro

n-Propyl 6-amino-2,6-dideoxy-2,2-difluoro-β-d-glucopyranoside is a good inhibitor for the β-galactosidase from E. coli

New amino acid clubbed Schiff bases inhibit carbonic anhydrase II, α-glucosidase, and urease enzymes: in silico and in vitro

Antibacterial and Cytotoxic Activity of Ruthenium‐ p ‐cymene Complexes with 2‐Methylquinolin‐8‐ol Derivatives

Apoptotic activity of substituted 3-O-acetyl-betulinic acid benzylamides

Design, synthesis and biological evaluation of novel pyrazolo[1,2,4]triazolopyrimidine derivatives as potential anticancer agents

Design, Synthesis and Biological Evaluation of Novel Pyrazolo[1,2,4]triazolopyrimidine Derivatives as Potential Anticancer Agents

Drugs, metabolites, and lung accumulating small lysosomotropic molecules: multiple targeting impedes SARS-CoV-2 infection and progress to COVID-19

Lineage-selective disturbance of early human hematopoietic progenitor cell differentiation by the commonly used plasticizer Di-2-ethylhexyl phthalate via reactive oxygen species: fatty acid oxidation makes the difference

Lineage-Selective Disturbance of Early Human Hematopoietic Progenitor Cell Differentiation by the Commonly Used Plasticizer Di-2-ethylhexyl Phthalate via Reactive Oxygen Species: Fatty Acid Oxidation Makes the Difference

Methacryloyl-GlcNAc Derivatives Copolymerized with Dimethacrylamide as a Novel Antibacterial and Biocompatible Coating

n-Propyl 6-amino-2,6-dideoxy-2,2-difluoro-β-D-glucopyranoside is a good inhibitor for the β-galactosidase from E. coli

Synthese und biologische Evaluierung von Naturstoffderivaten : [kumulative Dissertation]

Synthesis and structure of azelastine-N-oxides

The Presence of a Cyclohexyldiamine Moiety Confers Cytotoxicity to Pentacyclic Triterpenoids

Ester and amide derivatives of rhodamine B exert cytotoxic effects on different human tumor cell lines

Evaluation of cholinesterase inhibitory activity and cytotoxicity of synthetic derivatives of di- and triterpene metabolites from Pinus silvestris and Dipterocarpus alatus resins

Synthesis and cytotoxic evaluation of malachite green derived oleanolic and ursolic acid piperazineamides

Identification and quantification of cannabinol as a biomarker for local hemp retting in an ancient sedimentary record by HPTLC-ESI-MS

Total Synthesis of Surinamensinols A and B

Squaramide–Quaternary Ammonium Salt as an Effective Binary Organocatalytic System for Oxazolidinone Synthesis from Isocyanates and Epoxides

COVID-19/SARS-CoV-2 Infection: Lysosomes and Lysosomotropism Implicate New Treatment Strategies and Personal Risks

Metabolite Patterns in Human Myeloid Hematopoiesis Result from Lineage-Dependent Active Metabolic Pathways

Rational drug repurposing: focus on lysosomotropism, targets in disease process, drug profile, and pulmonary tissue accumulation in SARS-CoV-2 Infection/COVID-19

Rational Drug Repurposing: Focus on Lysosomotropism, Targets in Disease Process, Drug Profile, and Pulmonary Tissue Accumulation in SARS-CoV-2 Infection/COVID-19

Synthese und biologische Evaluierung von aromatischen Pflanzeninhaltsstoffen

Synthese und biologische Evaluierung von Zimtsäure-Derivaten

Mapping Natural Dyes in Archeological Textiles by Imaging Mass Spectrometry

Synthese antitumoraktiver Triterpen-Carbonsäure-Derivate : [kumulative Dissertation]

Synthese und biologische Evaluierung von Naturstoffanaloga hinsichtlich ihrer Inhibierung von Cholinesterasen

Synthese von Triterpenderivaten und ihre biologische Evaluierung : [kumulative Dissertation]

Platanic acid-derived methyl 20-amino-30-norlupan-28-oates are potent cytotoxic agents acting by apoptosis

Furanosyl Nucleoside Analogues Embodying Triazole or Theobromine Units as Potential Lead Molecules for Alzheimer's Disease

Drotaverine – a Concealed Cytostatic!

Synthesis of glucopyranos-6′-yl purine and pyrimidine isonucleosides as potential cholinesterase inhibitors. Access to pyrimidine-linked pseudodisaccharides through Mitsunobu reaction

Synthesis and Evaluation of the Biological Profile of Novel Analogues of Nucleosides and of Potential Mimetics of Sugar Phosphates and Nucleotides