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Harald Kolmar

Biochemiker

Name	Harald Kolmar
Place	Deutschland
Academic degree	Prof. Dr.
Profession	Biochemiker (characteristic profession)
Related	Technische Universität Darmstadt. Fachbereich Chemie Biochemie (Studienfach)
Source	Webseite: https://www.chemie.tu-darmstadt.de/forschung_5/arbeitsgruppen/alleprofessoren/professoren_einzelansicht_289.de.jsp (Stand: 25.10.19)
Record type	Person
GND-Identifier	1197913467
Record ID	1197913467
Involved in show all Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features Anti-idiotype antibodies for biomedical applications Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features Characterization of soy protein hydrolysates and influence of its iron content on monoclonal antibody production by a murine hybridoma cell line Conditional Cell Penetration of a Masked CPP and Optimization of Multimeric CPP-Delivery Modules for Intracellular Cargo Delivery Covalent Attachment of Enzymes to Paper Fibers for Paper-Based Analytical Devices Development of Innovative Bioconjugation Strategies for the Generation of Bi-Specific Antibodies Enabling Targeted Protein Degradation Dual Function pH Responsive Bispecific Antibodies for Tumor Targeting and Antigen Depletion in Plasma EGFR binding Fc domain-drug conjugates: stable and highly potent cytotoxic molecules mediate selective cell killing Engineering IgG-Like Bispecific Antibodies — An Overview Explorations towards the biocatalytic synthesis of a hazelnut aroma precursor Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteins Generation of a host cell line containing a MAR-rich landing pad for site-specific integration and expression of transgenes Humanization of Chicken‐Derived scFv Using Yeast Surface Display and NGS Data Mining Identification of novel antagonists against skin relevant molecular targets in mediation of itch and inflammation Intein mediated high throughput screening for bispecific antibodies Isolation of Common Light Chain Antibodies from Immunized Chickens Using Yeast Biopanning and Fluorescence‐Activated Cell Sorting Macrophages Cell Surface Proteome Analysis for Identification of Markers and Therapeutic Targets Merge Two into One: Multispecific Symmetric Antibodies for Cancer Immunotherapy Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity Mimicking the immunosuppressive impact of fibroblasts in a 3D multicellular spheroid model Modifikation von Proteinen mittels Photosensibilisatoren für die strukturierte Proteinimmobilisierung und Quervernetzung von Biomaterialien Modulation of the FKBP51 structure by protein engineering and isolation of conformation-locking antibodies and affibodies Multivalent dextran hybrids for efficient cytosolic delivery of biomolecular cargoes Optimierung der Astaxanthin-Synthese in Synechococcus sp. PCC7002 unter Zuhilfenahme synthetischer Biologie Penetration of Nanobody-Dextran Polymer Conjugates through Tumor Spheroids Peptide und Peptoide als Bindepartner für Chemokine Potent Apoptosis Induction by a Novel Trispecific B7-H3xCD16xTIGIT 2+1 Common Light Chain Natural Killer Cell Engager REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells Recombinant Antibody Production Using a Dual-Promoter Single Plasmid System Refined generation of chimeric antigen receptor T cells by dasatinib and urolithin A Review: High temperature short time treatment of cell culture media and feed solutions to mitigate adventitious viral contamination in the biopharmaceutical industry Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies Tag-free, specific conjugation of glycosylated IgG1 antibodies using microbial transglutaminase Targeted Phagocytosis Induction for Cancer Immunotherapy via Bispecific MerTK-Engaging Antibodies Targeted protein degradation of FK506-binding proteins Toward a robust lipid supplementation for SP2/0 fed-batch culture: Improving process performance by leveraging lipoprotein variability Using protein geometry to optimize cytotoxicity and the cytokine window of a ROR1 specific T cell engager Antibody-mediated inhibition of MHC class I chain-related protein A shedding for tumor therapy Engineering a high affine NMDAR-Fc “baitbody” fusion protein for autoantibody detection and elimination in NMDAR encephalitis Engineering of Bioactive Papers: Site-specific, Covalent Immobilization of Peptides and Proteins Entwicklung neuer Strategien zur spezifischen Hemmung humaner Histondeacetylase 8 Flavors of biotin ligases: From research tools towards biopharmaceutical applications Generation of a Host Cell line containing a MAR-rich landing pad for site specific integration and expression of transgenes Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody Generation of Multispecific Antibodies with Immune Cell Modulating Functions Hybrid Multimeric Architectures for Enhanced Receptor Targeting and Intracellular Delivery of Bioactive Cargoes In-cell analysis of FK506 binding protein 51-glucocorticoid receptor-heat shock protein 90 interaction at single residue resolution Modification of biomaterials for the immobilization and release of chemokines Synthesis and investigation of 2-substituted hetero-/arylacetic acids as bottom groups for selective inhibitors of the FK506-binding protein 51 (FKBP51) Untersuchungen zur Substrattoleranz von Sactisynthasen für die Generierung Thioether‐verbrückter Sactipeptide mit neuen Eigenschaften Sactipeptide Engineering by Probing the Substrate Tolerance of a Thioether‐Bond‐Forming Sactisynthase EGFR binding Fc domain-drug conjugates: stable and highly potent cytotoxic molecules mediate selective cell killing A Generic Strategy to Generate Bifunctional Two-in-One Antibodies by Chicken Immunization Analyzing the engineering potential of subtilosin A by probing the substrate promiscuity of the thioether forming sactisynthase AlbA Application of Transketolase from Geobacillus stearothermophilus for Broad Synthesis of N-Arylhydroxamates and Development of a Novel High-Throughput Reactivity Assay Binding pocket stabilization by high-throughput screening of yeast display libraries

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Katalog der Deutschen Nationalbibliothek

Harald Kolmar

Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features

Anti-idiotype antibodies for biomedical applications

Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies

Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies

Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features

Characterization of soy protein hydrolysates and influence of its iron content on monoclonal antibody production by a murine hybridoma cell line

Conditional Cell Penetration of a Masked CPP and Optimization of Multimeric CPP-Delivery Modules for Intracellular Cargo Delivery

Covalent Attachment of Enzymes to Paper Fibers for Paper-Based Analytical Devices

Development of Innovative Bioconjugation Strategies for the Generation of Bi-Specific Antibodies Enabling Targeted Protein Degradation

Dual Function pH Responsive Bispecific Antibodies for Tumor Targeting and Antigen Depletion in Plasma

EGFR binding Fc domain-drug conjugates: stable and highly potent cytotoxic molecules mediate selective cell killing

Engineering IgG-Like Bispecific Antibodies — An Overview

Explorations towards the biocatalytic synthesis of a hazelnut aroma precursor

Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteins

Generation of a host cell line containing a MAR-rich landing pad for site-specific integration and expression of transgenes

Humanization of Chicken‐Derived scFv Using Yeast Surface Display and NGS Data Mining

Identification of novel antagonists against skin relevant molecular targets in mediation of itch and inflammation

Intein mediated high throughput screening for bispecific antibodies

Isolation of Common Light Chain Antibodies from Immunized Chickens Using Yeast Biopanning and Fluorescence‐Activated Cell Sorting

Macrophages Cell Surface Proteome Analysis for Identification of Markers and Therapeutic Targets

Merge Two into One: Multispecific Symmetric Antibodies for Cancer Immunotherapy

Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity

Mimicking the immunosuppressive impact of fibroblasts in a 3D multicellular spheroid model

Modifikation von Proteinen mittels Photosensibilisatoren für die strukturierte Proteinimmobilisierung und Quervernetzung von Biomaterialien

Modulation of the FKBP51 structure by protein engineering and isolation of conformation-locking antibodies and affibodies

Multivalent dextran hybrids for efficient cytosolic delivery of biomolecular cargoes

Optimierung der Astaxanthin-Synthese in Synechococcus sp. PCC7002 unter Zuhilfenahme synthetischer Biologie

Penetration of Nanobody-Dextran Polymer Conjugates through Tumor Spheroids

Peptide und Peptoide als Bindepartner für Chemokine

Potent Apoptosis Induction by a Novel Trispecific B7-H3xCD16xTIGIT 2+1 Common Light Chain Natural Killer Cell Engager

REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells

Recombinant Antibody Production Using a Dual-Promoter Single Plasmid System

Refined generation of chimeric antigen receptor T cells by dasatinib and urolithin A

Review: High temperature short time treatment of cell culture media and feed solutions to mitigate adventitious viral contamination in the biopharmaceutical industry

Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries

Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies

Tag-free, specific conjugation of glycosylated IgG1 antibodies using microbial transglutaminase

Targeted Phagocytosis Induction for Cancer Immunotherapy via Bispecific MerTK-Engaging Antibodies

Targeted protein degradation of FK506-binding proteins

Toward a robust lipid supplementation for SP2/0 fed-batch culture: Improving process performance by leveraging lipoprotein variability

Using protein geometry to optimize cytotoxicity and the cytokine window of a ROR1 specific T cell engager

Antibody-mediated inhibition of MHC class I chain-related protein A shedding for tumor therapy

Engineering a high affine NMDAR-Fc “baitbody” fusion protein for autoantibody detection and elimination in NMDAR encephalitis

Engineering of Bioactive Papers: Site-specific, Covalent Immobilization of Peptides and Proteins

Entwicklung neuer Strategien zur spezifischen Hemmung humaner Histondeacetylase 8

Flavors of biotin ligases: From research tools towards biopharmaceutical applications

Generation of a Host Cell line containing a MAR-rich landing pad for site specific integration and expression of transgenes

Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody

Generation of Multispecific Antibodies with Immune Cell Modulating Functions

Hybrid Multimeric Architectures for Enhanced Receptor Targeting and Intracellular Delivery of Bioactive Cargoes

In-cell analysis of FK506 binding protein 51-glucocorticoid receptor-heat shock protein 90 interaction at single residue resolution

Modification of biomaterials for the immobilization and release of chemokines

Synthesis and investigation of 2-substituted hetero-/arylacetic acids as bottom groups for selective inhibitors of the FK506-binding protein 51 (FKBP51)

Untersuchungen zur Substrattoleranz von Sactisynthasen für die Generierung Thioether‐verbrückter Sactipeptide mit neuen Eigenschaften

Sactipeptide Engineering by Probing the Substrate Tolerance of a Thioether‐Bond‐Forming Sactisynthase

EGFR binding Fc domain-drug conjugates: stable and highly potent cytotoxic molecules mediate selective cell killing

A Generic Strategy to Generate Bifunctional Two-in-One Antibodies by Chicken Immunization

Analyzing the engineering potential of subtilosin A by probing the substrate promiscuity of the thioether forming sactisynthase AlbA

Application of Transketolase from Geobacillus stearothermophilus for Broad Synthesis of N-Arylhydroxamates and Development of a Novel High-Throughput Reactivity Assay

Binding pocket stabilization by high-throughput screening of yeast display libraries