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Michael Groll (1971-)

Biochemiker

Name	Michael Groll
Time	1971- (Date of birth and death)
Place	Deutschland
Gender	männlich
Academic degree	Prof,Dr. rer.nat.
Profession	Biochemiker (characteristic profession) Sachverständiger
Related	Technische Universität München
Further information	Diss. und Habil.-Schr. Fachbereich Biochemie
Record type	Person
GND-Identifier	121191990
Record ID	121191990
Involved in show all Hijacking a bacterial ABC transporter for genetic code expansion Unraveling the molecular basis of substrate specificity and halogen activation in vanadium-dependent haloperoxidases Molecular basis for azetidine-2-carboxylic acid biosynthesis Characterization of the OTU-domain deubiquitinating enzymes Otu2, OTUD6A and OTUD6B Tailored SirReal-type inhibitors enhance SIRT2 inhibition through ligand stabilization and disruption of NAD+ co-factor binding Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification Polyketide Trimming Shapes Dihydroxynaphthalene‐Melanin and Anthraquinone Pigments Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide Bioengineering of syrbactin megasynthetases for immunoproteasome inhibitor production Development of Pd-labile prodrugs for the prevention of biofilms & Investigation of the anti-proliferative target of Neocarzilin A Exploring the Multifaceted Utility of Small Molecule Probes for Tailored Antibiotic Therapy and Point-of-care Diagnostics Structural and Functional Characterizations of Proteins Involved in Pyrrolysine- and Cobalamin-dependent Methyl Transfer Structural and Functional Studies on Cyclic Protease Inhibitors and their Biosynthesis Structural and Functional Studies on Cyclic Protease Inhibitors and their Biosynthesis Structure of Staphylococcus aureus ClpP Bound to the Covalent Active‐Site Inhibitor Cystargolide A Structure of Staphylococcus aureus ClpP Bound to the Covalent Active‐Site Inhibitor Cystargolide A Structure of Staphylococcus aureus ClpP Bound to the Covalent Active‐Site Inhibitor Cystargolide A Eine chemisch‐proteomische Strategie identifiziert Inhibitoren der Lipoat‐Wiederverwertung in Bakterien und Parasiten A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites 1. Strukturelle und funktionelle Charakterisierung der metallabhängigen Isoprenyldiphosphatsynthase PcIDS1; 2. Strukturelle und funktionelle Charakterisierung der Terpencyclase MstE aus aquatischen Cyanobakterien Chemical proteomic studies into the human side-effects of fluoroquinolone antibiotics and elucidation of the dual mode of action of novel indolin-2-one nitroimidazole antibiotics Holistic optimization of single cell oil processes: Creating and controlling the genetic toolbox as well as cultivation processes Investigation of innovative cofactor-based antimicrobial strategies against bacteria and parasites by chemical proteomics Mechanistic Studies on Polyketide Biosynthesis in Pathogenic Fungi and Bacteria A Specialized Polythioamide‐Binding Protein Confers Antibiotic Self‐Resistance in Anaerobic Bacteria A Specialized Polythioamide‐Binding Protein Confers Antibiotic Self‐Resistance in Anaerobic Bacteria Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria A Specialized Polythioamide‐Binding Protein Confers Antibiotic Self‐Resistance in Anaerobic Bacteria Computational studies of charged networks in protein regulation and function Evolution inspired engineering of megasynthetases Evolution inspired engineering of megasynthetases Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria Multi-scale modeling and computational design of biological proton/ion-transport modules Strukturelle und mechanistische Einblicke in die Bildung der C‐S‐Bindungen in Gliotoxin Structural and Mechanistic Insights into C−S Bond Formation in Gliotoxin Estimation of soil erosion and sediment yield concentration across the Kolleru Lake catchment using GIS Activation, Structure, Biosynthesis and Bioactivity of Glidobactin‐like Proteasome Inhibitors from Photorhabdus laumondii Front Cover: Activation, Structure, Biosynthesis and Bioactivity of Glidobactin‐like Proteasome Inhibitors from Photorhabdus laumondii (ChemBioChem 9/2021) Activation, structure, biosynthesis and bioactivity of glidobactin-like proteasome inhibitors from Photorhabdus laumondii Function and Design of Protein Conformational Switches Mechanistic Analysis of the Membrane-Associated MinDE Reaction Cycle Negative Regulation of HIF1α by the E3 Ligases RNF8 and TRAF6 Spatial and temporal gradients in the rate of dust deposition and aerosol optical thickness in southwestern Iran Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis Functional Characterisation of ClpP Mutations Conferring Resistance to Acyldepsipeptide Antibiotics in Firmicutes Structures in Tetrahydrofolate Methylation in Desulfitobacterial Glycine Betaine Metabolism at Atomic Resolution Front Cover: Structures in Tetrahydrofolate Methylation in Desulfitobacterial Glycine Betaine Metabolism at Atomic Resolution (ChemBioChem 6/2020) Biokatalytische Halogenierung: Studien zu neuartigen Vanadium-abhängigen Haloperoxidasen und deren Anwendung Investigations into (cyano-)bacterial secondary metabolite biosynthesis in heterologous expression systems Studien zur thermischen und mechanischen Modifikation und zum Puroindolingehalt von Weizenmehl Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB Defective immuno- and thymoproteasome assembly causes severe immunodeficiency Catalytic mechanism and molecular engineering of quinolone biosynthesis in dioxygenase AsqJ Eisenaufnahme in Pilzen der Gattung Aspergillus: strukturelle und biochemische Einblicke in Siderophoresterasen Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases 1. Structural and Mechanistic Characterization of a Type II Polyketide Synthase involved in Anthraquinone Biosynthesis 2. Structural and Mechanistic Characterization of the FeII/α-Ketoglutarate-dependent Dioxygenase AsqJ Characterization of a novel mouse line with an immunological phenotype, identification of the causative mutation and the underlying pathomechanism

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Katalog der Deutschen Nationalbibliothek

Michael Groll (1971-)

Hijacking a bacterial ABC transporter for genetic code expansion

Unraveling the molecular basis of substrate specificity and halogen activation in vanadium-dependent haloperoxidases

Molecular basis for azetidine-2-carboxylic acid biosynthesis

Characterization of the OTU-domain deubiquitinating enzymes Otu2, OTUD6A and OTUD6B

Tailored SirReal-type inhibitors enhance SIRT2 inhibition through ligand stabilization and disruption of NAD+ co-factor binding

Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification

Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification

Polyketide Trimming Shapes Dihydroxynaphthalene‐Melanin and Anthraquinone Pigments

Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide

Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide

Bioengineering of syrbactin megasynthetases for immunoproteasome inhibitor production

Development of Pd-labile prodrugs for the prevention of biofilms & Investigation of the anti-proliferative target of Neocarzilin A

Exploring the Multifaceted Utility of Small Molecule Probes for Tailored Antibiotic Therapy and Point-of-care Diagnostics

Structural and Functional Characterizations of Proteins Involved in Pyrrolysine- and Cobalamin-dependent Methyl Transfer

Structural and Functional Studies on Cyclic Protease Inhibitors and their Biosynthesis

Structural and Functional Studies on Cyclic Protease Inhibitors and their Biosynthesis

Structure of Staphylococcus aureus ClpP Bound to the Covalent Active‐Site Inhibitor Cystargolide A

Structure of Staphylococcus aureus ClpP Bound to the Covalent Active‐Site Inhibitor Cystargolide A

Structure of Staphylococcus aureus ClpP Bound to the Covalent Active‐Site Inhibitor Cystargolide A

Eine chemisch‐proteomische Strategie identifiziert Inhibitoren der Lipoat‐Wiederverwertung in Bakterien und Parasiten

A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites

1. Strukturelle und funktionelle Charakterisierung der metallabhängigen Isoprenyldiphosphatsynthase PcIDS1; 2. Strukturelle und funktionelle Charakterisierung der Terpencyclase MstE aus aquatischen Cyanobakterien

Chemical proteomic studies into the human side-effects of fluoroquinolone antibiotics and elucidation of the dual mode of action of novel indolin-2-one nitroimidazole antibiotics

Holistic optimization of single cell oil processes: Creating and controlling the genetic toolbox as well as cultivation processes

Investigation of innovative cofactor-based antimicrobial strategies against bacteria and parasites by chemical proteomics

Mechanistic Studies on Polyketide Biosynthesis in Pathogenic Fungi and Bacteria

A Specialized Polythioamide‐Binding Protein Confers Antibiotic Self‐Resistance in Anaerobic Bacteria

A Specialized Polythioamide‐Binding Protein Confers Antibiotic Self‐Resistance in Anaerobic Bacteria

Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead

Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria

A Specialized Polythioamide‐Binding Protein Confers Antibiotic Self‐Resistance in Anaerobic Bacteria

Computational studies of charged networks in protein regulation and function

Evolution inspired engineering of megasynthetases

Evolution inspired engineering of megasynthetases

Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria

Multi-scale modeling and computational design of biological proton/ion-transport modules

Strukturelle und mechanistische Einblicke in die Bildung der C‐S‐Bindungen in Gliotoxin

Structural and Mechanistic Insights into C−S Bond Formation in Gliotoxin

Estimation of soil erosion and sediment yield concentration across the Kolleru Lake catchment using GIS

Activation, Structure, Biosynthesis and Bioactivity of Glidobactin‐like Proteasome Inhibitors from Photorhabdus laumondii

Front Cover: Activation, Structure, Biosynthesis and Bioactivity of Glidobactin‐like Proteasome Inhibitors from Photorhabdus laumondii (ChemBioChem 9/2021)

Activation, structure, biosynthesis and bioactivity of glidobactin-like proteasome inhibitors from Photorhabdus laumondii

Function and Design of Protein Conformational Switches

Mechanistic Analysis of the Membrane-Associated MinDE Reaction Cycle

Negative Regulation of HIF1α by the E3 Ligases RNF8 and TRAF6

Spatial and temporal gradients in the rate of dust deposition and aerosol optical thickness in southwestern Iran

Structural snapshots of the minimal PKS system responsible for octaketide biosynthesis

Functional Characterisation of ClpP Mutations Conferring Resistance to Acyldepsipeptide Antibiotics in Firmicutes

Structures in Tetrahydrofolate Methylation in Desulfitobacterial Glycine Betaine Metabolism at Atomic Resolution

Front Cover: Structures in Tetrahydrofolate Methylation in Desulfitobacterial Glycine Betaine Metabolism at Atomic Resolution (ChemBioChem 6/2020)

Biokatalytische Halogenierung: Studien zu neuartigen Vanadium-abhängigen Haloperoxidasen und deren Anwendung

Investigations into (cyano-)bacterial secondary metabolite biosynthesis in heterologous expression systems

Studien zur thermischen und mechanischen Modifikation und zum Puroindolingehalt von Weizenmehl

Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB

Defective immuno- and thymoproteasome assembly causes severe immunodeficiency

Catalytic mechanism and molecular engineering of quinolone biosynthesis in dioxygenase AsqJ

Eisenaufnahme in Pilzen der Gattung Aspergillus: strukturelle und biochemische Einblicke in Siderophoresterasen

Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases

1. Structural and Mechanistic Characterization of a Type II Polyketide Synthase involved in Anthraquinone Biosynthesis 2. Structural and Mechanistic Characterization of the FeII/α-Ketoglutarate-dependent Dioxygenase AsqJ

Characterization of a novel mouse line with an immunological phenotype, identification of the causative mutation and the underlying pathomechanism