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Klaus Aktories (1948-)

Pharmakologe

Name	Klaus Aktories
Time	1948- (Date of birth and death)
Place	Wanne-Eickel (Geburtsort) Freiburg im Breisgau (Wirkungsort) Deutschland
Gender	männlich
Academic degree	Prof. Dr. med. Dr. rer. nat.
Profession	Pharmakologe (characteristic profession) Arzt Hochschullehrer
Variant	K. Aktories
Related	Albert-Ludwigs-Universität Freiburg. Institut für Pharmakologie und Toxikologie (1995-) Deutsche Akademie der Naturforscher Leopoldina (Mitglied, Matrikelnummer 06908) (2003-)
Topic	Personen zu Bildungswesen Personen zu Medizin, Tiermedizin
Source	Landesbibliographie Baden-Württemberg
Record type	Person
GND-Identifier	121590712
Record ID	121590712
Involved in show all Tyrosine-modifying glycosylation by Yersinia effectors Antibodies Directed Against GalNAc‐ and GlcNAc‐ O‐ Tyrosine Posttranslational Modifications – a New Tool for Glycoproteomic Detection Antibodies directed against GalNAc‐ and GlcNAc‐O‐tyrosine posttranslational modifications – a new tool for glycoproteomic detection From signal transduction to protein toxins - a narrative review about milestones on the research route of C. difficile toxins From signal transduction to protein toxins—a narrative review about milestones on the research route of C. difficile toxins Allgemeine und spezielle Pharmakologie und Toxikologie Allgemeine und spezielle Pharmakologie und Toxikologie : Lehrbuch und Nachschlagewerk für Studierende der Medizin, Zahnmedizin, Pharmazie und Veterinärmedizin, für Ärzte, Zahnärzte, Apotheker und Tierärzte sowie für Wissenschaftlerinnen und Wissenschaftler verwandter Disziplinen Another surprise in receptor binding of C. difficile toxins Clostridioides difficile binary toxin is recognized by the toll-like receptor 2/6 heterodimer to induce a nuclear factor-κB response Defined stereoisomers of 2″-amino NAD+ and their activity against human sirtuins and a bacterial (ADP-ribosyl) transferase Inhibition of Arp2/3 complex after ADP-ribosylation of Arp2 by binary clostridioides toxins Treatment of ovarian cancer with modified anthrax toxin Involvement of N‐glycans in binding of Photorhabdus luminescens Tc toxin The compound U18666A inhibits the intoxication of cells by clostridioides difficile toxins TcdA and TcdB The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state Human a-Defensin-5 efficiently neutralizes clostridioides difficile toxins TcdA, TcdB, and CDT Human peptide [alpha]‐defensin‐1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT Human peptide α‐defensin‐1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT Human α-defensin-5 efficiently neutralizes clostridioides difficile toxins TcdA, TcdB, and CDT Human α-defensin-5 efficiently neutralizes costridioides difficile toxins TcdA, TcdB, and CDT Inverse control of Rab proteins by Yersinia ADP-ribosyltransferase and glycosyltransferase related to clostridial glucosylating toxins Semaphorins or frizzled - it is the receptor that direct the action of clostridial glucosylating toxins Structure-function analysis of the photorhabdus Tc toxin complex cAMP guided his way: a life for G protein-mediated signal transduction and molecular pharmacology—tribute to Karl H. Jakobs Charakterisierung der bakteriellen Toxine YART und YGT aus Yersinia mollaretii Charakterisierung der Struktur, Spezifität und Funktion von Yersinia enterocolitica- und Yersinia kristensenii-Glykosyltransferasen Engineering Photorhabdus luminescens toxin complex (PTC) into a recombinant injection nanomachine The Legionella effector LtpM is a new type of phosphoinositide-activated glucosyltransferase Untersuchungen über den molekularen Mechanismus und die zellulären Wirkungen des Effektorproteins SseI aus Salmonella Typhimurium Characterization of the glucosyltransferase activity of Legionella pneumophila effector SetA Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin Die Aufnahme von Photorhabdus luminescens-Toxinen in eukaryotische Zellen Effekte des Pasteurella multocida-Toxins auf Osteozyten Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin Involvement of osteocytes in the action of Pasteurella multocida toxin Novel cytotoxic glycosyltransferase effectors of Legionella Salmonella Typhimurium effector SseI inhibits chemotaxis and increases host cell survival by deamidation of heterotrimeric Gi proteins Septin remodeling is essential for the formation of cell membrane protrusions (microtentacles) in detached tumor cells Studies on the effects of Pasteurella multocida toxin in a cell culture model of fibrodysplasia ossificans progressiva Targeting oncogenic Ras by the Clostridium perfringens toxin TpeL The regulation of septins in ciliogenesis and septin functions beyond the diffusion barrier Allgemeine und spezielle Pharmakologie und Toxikologie : Begründet von W. Forth, D. Henschler, W. Rummel Allgemeine und spezielle Pharmakologie und Toxikologie : für Studenten der Medizin, Veterinärmedizin, Pharmazie, Chemie und Biologie sowie für Ärzte, Tierärzte und Apotheker Auranofin inhibits the elnzyme activity of pasteurella multocida toxin PMT in human cells and protects cells from intoxication Auranofin inhibits the enzyme activity of Pasteurella multocida toxin PMT in human cells and protects cells from intoxication Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo-2 cells Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A Septin remodeling is essential for the formation of cell membrane protrusions (microtentacles) in detached tumor cells Specific role of RhoC in tumor invasion and metastasis Targeted delivery of an ADP-ribosylating bacterial toxin into cancer cells The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells EGA protects mammalian cells from Clostridium difficile CDT, Clostridium perfringens iota toxin, and Clostridium botulinum C2 toxin Charakterisierung zytotoxischer Pasteurella multocida-Toxin–Chimären Lu/BCAM Adhesion Glycoprotein Is a Receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1) Roles of Asp179 and Glu270 in ADP-ribosylation of Actin by Clostridium perfringens Iota Toxin Selection of nanobodies that block the enzymatic and cytotoxic activities of the binary clostridium difficile toxin CDT The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos

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Katalog der Deutschen Nationalbibliothek

Klaus Aktories (1948-)

Tyrosine-modifying glycosylation by Yersinia effectors

Antibodies Directed Against GalNAc‐ and GlcNAc‐ O‐ Tyrosine Posttranslational Modifications – a New Tool for Glycoproteomic Detection

Antibodies directed against GalNAc‐ and GlcNAc‐O‐tyrosine posttranslational modifications – a new tool for glycoproteomic detection

From signal transduction to protein toxins - a narrative review about milestones on the research route of C. difficile toxins

From signal transduction to protein toxins—a narrative review about milestones on the research route of C. difficile toxins

Allgemeine und spezielle Pharmakologie und Toxikologie

Allgemeine und spezielle Pharmakologie und Toxikologie : Lehrbuch und Nachschlagewerk für Studierende der Medizin, Zahnmedizin, Pharmazie und Veterinärmedizin, für Ärzte, Zahnärzte, Apotheker und Tierärzte sowie für Wissenschaftlerinnen und Wissenschaftler verwandter Disziplinen

Another surprise in receptor binding of C. difficile toxins

Clostridioides difficile binary toxin is recognized by the toll-like receptor 2/6 heterodimer to induce a nuclear factor-κB response

Defined stereoisomers of 2″-amino NAD+ and their activity against human sirtuins and a bacterial (ADP-ribosyl) transferase

Inhibition of Arp2/3 complex after ADP-ribosylation of Arp2 by binary clostridioides toxins

Treatment of ovarian cancer with modified anthrax toxin

Involvement of N‐glycans in binding of Photorhabdus luminescens Tc toxin

The compound U18666A inhibits the intoxication of cells by clostridioides difficile toxins TcdA and TcdB

The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB

Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state

Human a-Defensin-5 efficiently neutralizes clostridioides difficile toxins TcdA, TcdB, and CDT

Human peptide [alpha]‐defensin‐1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT

Human peptide α‐defensin‐1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT

Human α-defensin-5 efficiently neutralizes clostridioides difficile toxins TcdA, TcdB, and CDT

Human α-defensin-5 efficiently neutralizes costridioides difficile toxins TcdA, TcdB, and CDT

Inverse control of Rab proteins by Yersinia ADP-ribosyltransferase and glycosyltransferase related to clostridial glucosylating toxins

Semaphorins or frizzled - it is the receptor that direct the action of clostridial glucosylating toxins

Structure-function analysis of the photorhabdus Tc toxin complex

cAMP guided his way: a life for G protein-mediated signal transduction and molecular pharmacology—tribute to Karl H. Jakobs

Charakterisierung der bakteriellen Toxine YART und YGT aus Yersinia mollaretii

Charakterisierung der Struktur, Spezifität und Funktion von Yersinia enterocolitica- und Yersinia kristensenii-Glykosyltransferasen

Engineering Photorhabdus luminescens toxin complex (PTC) into a recombinant injection nanomachine

The Legionella effector LtpM is a new type of phosphoinositide-activated glucosyltransferase

Untersuchungen über den molekularen Mechanismus und die zellulären Wirkungen des Effektorproteins SseI aus Salmonella Typhimurium

Characterization of the glucosyltransferase activity of Legionella pneumophila effector SetA

Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin

Die Aufnahme von Photorhabdus luminescens-Toxinen in eukaryotische Zellen

Effekte des Pasteurella multocida-Toxins auf Osteozyten

Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin

Involvement of osteocytes in the action of Pasteurella multocida toxin

Novel cytotoxic glycosyltransferase effectors of Legionella

Salmonella Typhimurium effector SseI inhibits chemotaxis and increases host cell survival by deamidation of heterotrimeric Gi proteins

Septin remodeling is essential for the formation of cell membrane protrusions (microtentacles) in detached tumor cells

Studies on the effects of Pasteurella multocida toxin in a cell culture model of fibrodysplasia ossificans progressiva

Targeting oncogenic Ras by the Clostridium perfringens toxin TpeL

The regulation of septins in ciliogenesis and septin functions beyond the diffusion barrier

Allgemeine und spezielle Pharmakologie und Toxikologie : Begründet von W. Forth, D. Henschler, W. Rummel

Allgemeine und spezielle Pharmakologie und Toxikologie : für Studenten der Medizin, Veterinärmedizin, Pharmazie, Chemie und Biologie sowie für Ärzte, Tierärzte und Apotheker

Auranofin inhibits the elnzyme activity of pasteurella multocida toxin PMT in human cells and protects cells from intoxication

Auranofin inhibits the enzyme activity of Pasteurella multocida toxin PMT in human cells and protects cells from intoxication

Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells

Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo-2 cells

Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A

Septin remodeling is essential for the formation of cell membrane protrusions (microtentacles) in detached tumor cells

Specific role of RhoC in tumor invasion and metastasis

Targeted delivery of an ADP-ribosylating bacterial toxin into cancer cells

The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells

EGA protects mammalian cells from Clostridium difficile CDT, Clostridium perfringens iota toxin, and Clostridium botulinum C2 toxin

Charakterisierung zytotoxischer Pasteurella multocida-Toxin–Chimären

Lu/BCAM Adhesion Glycoprotein Is a Receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1)

Roles of Asp179 and Glu270 in ADP-ribosylation of Actin by Clostridium perfringens Iota Toxin

Selection of nanobodies that block the enzymatic and cytotoxic activities of the binary clostridium difficile toxin CDT

The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation

Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos