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Michael Platten (1971-)

Name	Michael Platten
Time	1971- (Date of birth and death)
Place	Bonn (Geburtsort) Heidelberg (Wirkungsort) Deutschland
Gender	männlich
Academic degree	Prof. Dr. med.
Variant	M. Platten
Related	Jana K. Sonner (berufliche Beziehung) Klinikum Heidelberg (bis 31.08.2016) Medizin (Studienfach)
Further information	Habil. Fachgebiet Allgemeine Neurologie an der Univ. Freiburg; Wissenschaftlicher Mitarbeiter ehemals leitender Oberarzt der Abteilung Neuroonkologie der Neurologischen Klinik der Universität Heidelberg; seit September 2016 Direktor der Neurologischen Klinik der Medizinischen Fakultät Mannheim der Universität Heidelberg
Record type	Person
GND-Identifier	121627780
Record ID	121627780
Involved in show all Bottom-up synthetic immunology L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy Machine learning-guided prediction of tumor-reactive T cell receptors Concurrent gliomas in patients with multiple sclerosis Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15 INTERCEPT H3: a multicenter phase I peptide vaccine trial for the treatment of H3-mutated diffuse midline gliomas A H3K27M-targeted vaccine in adults with diffuse midline glioma Myeloid cell iron uptake pathways and paramagnetic rim formation in multiple sclerosis Approaches to address the immunogenicity and immunosuppressive features of Isocitrate Dehydrogenase 1 mutated gliomas Autologous haematopoietic stem cell transplantation for multiple sclerosis: a position paper and registry outline Autologous haematopoietic stem cell transplantation for multiple sclerosis: a position paper and registry outline Dysfunctional dendritic cells limit antigen-specific T cell response in glioma Identification and characterization of T cell receptors reactive to the E7(11-19) epitope of HPV-16 Identification and validation of neoepitope-specific T cell receptors for glioma immunotherapy Identifizierung und Charakterisierung antigenspezifischer T-Zell-Antworten gegen Glioblastome Impact of disease-modifying therapies on evolving tissue damage in iron rim multiple sclerosis lesions Non-invasive tracking of T cell recruitment to the tumor microenvironment in a murine glioma model by high field cellular magnetic resonance imaging T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients Veränderungen des Tumormikromilieus durch zelluläre Immuntherapien in experimentellen Tumormodellen Clinical and Translational Advances in Glioma Immunotherapy Activation of non-classical NMDA receptors by glycine impairs barrier function of brain endothelial cells Improvement of functional outcome for patients with newly diagnosed grade 2 or 3 gliomas with co-deletion of 1p/19q – IMPROVE CODEL: the NOA-18 trial The remains of the day: neuropsychological findings in postacute transient global amnesia MRI predictors for the conversion from contrast-enhancing to iron rim multiple sclerosis lesions Evaluating the role of the aryl hydrocarbon receptor and CXCL10 in regulating the tumour immune microenvironment Identification of myeloid cell targets for cancer immunotherapy using CRISPR screening In vivo Darstellung von Immunzellen mittels Eisenoxid-Nanopartikeln und MRT in einem Modell der Multiplen Sklerose The effect of dietary tryptophan deprivation on autoreactive T cells and the gut microbiome Association of iron rim lesions with brain and cervical cord volume in relapsing multiple sclerosis Intrathecal activation of CD8 + memory T cells in IgG4‐related disease of the brain parenchyma Chronobiology of transient global amnesia A vaccine targeting mutant IDH1 in newly diagnosed glioma Charakterisierung der TDO-vermittelten Immunsuppression in experimentellen Gliomen Comparative evaluation of T cell receptors in experimental glioma-draining lymph nodes Identification of Myeloid Cell Targets for Cancer Immunotherapy Major Histocompatibility Complex Class II Antigen Responses as Drivers of Brain Tumor Immunity Modulation of antitumor immunity by isocitrate dehydrogenase-mutated tumors Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies The therapeutic potential of targeting tryptophan catabolism in cancer Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities Therapieassoziierte neurologische Symptome onkologischer Patienten und deren Behandlung Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond Actively personalized vaccination trial for newly diagnosed glioblastoma Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience Novel, improved grading system(s) for IDH-mutant astrocytic gliomas Vaccine Strategies in Gliomas Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies Concepts for Immunotherapies in Gliomas Immuntherapien bei Gliomen Suppression of Th1 differentiation by tryptophan supplementation in vivo Interaktion zwischen Herz und Hirn bei plötzlichem Herztod Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas Increasing the sensitivity of MRI for the detection of multiple sclerosis lesions by long axial coverage of the spinal cord: a prospective study in 119 patients

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Katalog der Deutschen Nationalbibliothek

Michael Platten (1971-)

Bottom-up synthetic immunology

L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial

Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy

Machine learning-guided prediction of tumor-reactive T cell receptors

Concurrent gliomas in patients with multiple sclerosis

Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15

INTERCEPT H3: a multicenter phase I peptide vaccine trial for the treatment of H3-mutated diffuse midline gliomas

A H3K27M-targeted vaccine in adults with diffuse midline glioma

Myeloid cell iron uptake pathways and paramagnetic rim formation in multiple sclerosis

Approaches to address the immunogenicity and immunosuppressive features of Isocitrate Dehydrogenase 1 mutated gliomas

Autologous haematopoietic stem cell transplantation for multiple sclerosis: a position paper and registry outline

Autologous haematopoietic stem cell transplantation for multiple sclerosis: a position paper and registry outline

Dysfunctional dendritic cells limit antigen-specific T cell response in glioma

Identification and characterization of T cell receptors reactive to the E7(11-19) epitope of HPV-16

Identification and validation of neoepitope-specific T cell receptors for glioma immunotherapy

Identifizierung und Charakterisierung antigenspezifischer T-Zell-Antworten gegen Glioblastome

Impact of disease-modifying therapies on evolving tissue damage in iron rim multiple sclerosis lesions

Non-invasive tracking of T cell recruitment to the tumor microenvironment in a murine glioma model by high field cellular magnetic resonance imaging

T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles

The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients

Veränderungen des Tumormikromilieus durch zelluläre Immuntherapien in experimentellen Tumormodellen

Clinical and Translational Advances in Glioma Immunotherapy

Activation of non-classical NMDA receptors by glycine impairs barrier function of brain endothelial cells

Improvement of functional outcome for patients with newly diagnosed grade 2 or 3 gliomas with co-deletion of 1p/19q – IMPROVE CODEL: the NOA-18 trial

The remains of the day: neuropsychological findings in postacute transient global amnesia

MRI predictors for the conversion from contrast-enhancing to iron rim multiple sclerosis lesions

Evaluating the role of the aryl hydrocarbon receptor and CXCL10 in regulating the tumour immune microenvironment

Identification of myeloid cell targets for cancer immunotherapy using CRISPR screening

In vivo Darstellung von Immunzellen mittels Eisenoxid-Nanopartikeln und MRT in einem Modell der Multiplen Sklerose

The effect of dietary tryptophan deprivation on autoreactive T cells and the gut microbiome

Association of iron rim lesions with brain and cervical cord volume in relapsing multiple sclerosis

Intrathecal activation of CD8 + memory T cells in IgG4‐related disease of the brain parenchyma

Chronobiology of transient global amnesia

A vaccine targeting mutant IDH1 in newly diagnosed glioma

Charakterisierung der TDO-vermittelten Immunsuppression in experimentellen Gliomen

Comparative evaluation of T cell receptors in experimental glioma-draining lymph nodes

Identification of Myeloid Cell Targets for Cancer Immunotherapy

Major Histocompatibility Complex Class II Antigen Responses as Drivers of Brain Tumor Immunity

Modulation of antitumor immunity by isocitrate dehydrogenase-mutated tumors

Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas

EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood

INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies

The therapeutic potential of targeting tryptophan catabolism in cancer

Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities

Therapieassoziierte neurologische Symptome onkologischer Patienten und deren Behandlung

Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond

Actively personalized vaccination trial for newly diagnosed glioblastoma

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience

Novel, improved grading system(s) for IDH-mutant astrocytic gliomas

Vaccine Strategies in Gliomas

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations

Fourier Transform Infrared Microscopy Enables Guidance of Automated Mass Spectrometry Imaging to Predefined Tissue Morphologies

Concepts for Immunotherapies in Gliomas

Immuntherapien bei Gliomen

Suppression of Th1 differentiation by tryptophan supplementation in vivo

Interaktion zwischen Herz und Hirn bei plötzlichem Herztod

Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo

Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas

Increasing the sensitivity of MRI for the detection of multiple sclerosis lesions by long axial coverage of the spinal cord: a prospective study in 119 patients