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Thorsten Stiewe (1970-)

Name	Thorsten Stiewe
Time	1970- (Date of birth and death)
Academic degree	Dr. med.
Further information	Habil. Fach Biochemie und Molekularbiologie an der Univ. Würzburg; Diss. Fachbereich Medizin
Record type	Person
GND-Identifier	122317998
Record ID	122317998
Involved in show all TP53: the unluckiest of genes? Transcriptomic response of prostate cancer cells to carbon ion and photon irradiation with focus on androgen receptor and TP53 signaling BAG6 restricts pancreatic cancer progression by suppressing the release of IL33-presenting extracellular vesicles and the activation of mast cells KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma miR-147b mediated suppression of DUSP8 promotes lung cancer progression Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain Mutant p53-ENTPD5 control of the calnexin/calreticulin cycle: a druggable target for inhibiting integrin-α5-driven metastasis Robustness of the Autophagy Pathway to Somatic Copy Number Losses The lysophosphatidic acid-regulated signal transduction network in ovarian cancer cells and its role in actomyosin dynamics, cell migration and entosis Transcriptomic comparison of primary human lung cells with lung tissue samples and the human A549 lung cell line highlights cell type specific responses during infections with influenza A virus Lactate induces metabolic and epigenetic reprogramming of pro‐inflammatory Th17 cells Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase The importin beta superfamily member RanBP17 exhibits a role in cell proliferation and is associated with improved survival of patients with HPV+ HNSCC IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity Partial p53 reactivation is sufficient to induce cancer regression Modulation of Pancreatic Neuroendocrine Neoplastic Cell Fate by Autophagy-Mediated Death mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability Distinct IL‐1α‐responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner Drug-adapted cancer cell lines reveal drug-induced heterogeneity and enable the identification of biomarker candidates for the acquired resistance setting Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: a potential treatment of lung cancer YM155-adapted cancer cell lines reveal drug-induced heterogeneity and enable the identification of biomarker candidates for the acquired resistance setting SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex TP53 mutations and drug sensitivity in acute myeloid leukaemia cells with acquired MDM2 inhibitor resistance Interferon signaling in ascites-associated macrophages is linked to a favorable clinical outcome in a subgroup of ovarian carcinoma patients Altered glycogen metabolism causes hepatomegaly following an Atg7 deletion Galectin-3 interacts with components of the nuclear ribonucleoprotein complex A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome Characterization of the p53 Cistrome - DNA Binding Cooperativity Dissects p53's Tumor Suppressor Functions Effects of YM155 on survivin levels and viability in neuroblastoma cells with acquired drug resistance Antithetical NFAT c1–Sox2 and p53–miR200 signaling networks govern pancreatic cancer cell plasticity Immune and inflammatory cell composition of human lung cancer stroma p53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells Bedeutung des p73-Gens in der Tumorforschung und Entwicklungsbiologie Identifizierung und Charakterisierung eines neuen E1A-induzierten Apoptose-Mechanismus mit transformations-supprimierender Bedeutung in vivo

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Katalog der Deutschen Nationalbibliothek

Thorsten Stiewe (1970-)

TP53: the unluckiest of genes?

Transcriptomic response of prostate cancer cells to carbon ion and photon irradiation with focus on androgen receptor and TP53 signaling

BAG6 restricts pancreatic cancer progression by suppressing the release of IL33-presenting extracellular vesicles and the activation of mast cells

KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma

miR-147b mediated suppression of DUSP8 promotes lung cancer progression

Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

Mutant p53-ENTPD5 control of the calnexin/calreticulin cycle: a druggable target for inhibiting integrin-α5-driven metastasis

Robustness of the Autophagy Pathway to Somatic Copy Number Losses

The lysophosphatidic acid-regulated signal transduction network in ovarian cancer cells and its role in actomyosin dynamics, cell migration and entosis

Transcriptomic comparison of primary human lung cells with lung tissue samples and the human A549 lung cell line highlights cell type specific responses during infections with influenza A virus

Lactate induces metabolic and epigenetic reprogramming of pro‐inflammatory Th17 cells

Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase

The importin beta superfamily member RanBP17 exhibits a role in cell proliferation and is associated with improved survival of patients with HPV+ HNSCC

IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity

Partial p53 reactivation is sufficient to induce cancer regression

Modulation of Pancreatic Neuroendocrine Neoplastic Cell Fate by Autophagy-Mediated Death

mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability

Distinct IL‐1α‐responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner

Drug-adapted cancer cell lines reveal drug-induced heterogeneity and enable the identification of biomarker candidates for the acquired resistance setting

Reprogramming of tumor-associated macrophages by targeting β-catenin/FOSL2/ARID5A signaling: a potential treatment of lung cancer

YM155-adapted cancer cell lines reveal drug-induced heterogeneity and enable the identification of biomarker candidates for the acquired resistance setting

SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses

PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex

TP53 mutations and drug sensitivity in acute myeloid leukaemia cells with acquired MDM2 inhibitor resistance

Interferon signaling in ascites-associated macrophages is linked to a favorable clinical outcome in a subgroup of ovarian carcinoma patients

Altered glycogen metabolism causes hepatomegaly following an Atg7 deletion

Galectin-3 interacts with components of the nuclear ribonucleoprotein complex

A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome

Characterization of the p53 Cistrome - DNA Binding Cooperativity Dissects p53's Tumor Suppressor Functions

Effects of YM155 on survivin levels and viability in neuroblastoma cells with acquired drug resistance

Antithetical NFAT c1–Sox2 and p53–miR200 signaling networks govern pancreatic cancer cell plasticity

Immune and inflammatory cell composition of human lung cancer stroma

p53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo

Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells

Bedeutung des p73-Gens in der Tumorforschung und Entwicklungsbiologie

Identifizierung und Charakterisierung eines neuen E1A-induzierten Apoptose-Mechanismus mit transformations-supprimierender Bedeutung in vivo