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Jindrich Cinatl

Arzt

Name	Jindrich Cinatl
Place	Deutschland
Gender	männlich
Academic degree	Prof. Dr.
Profession	Arzt (characteristic profession) Hochschullehrer
Related	Institut für Medizinische Virologie (Frankfurt am Main)
Record type	Person
GND-Identifier	1275992072
Record ID	1275992072
Involved in show all A Monoclonal Human Alveolar Epithelial Cell Line (“Arlo”) with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections A Monoclonal Human Alveolar Epithelial Cell Line ("Arlo") with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform Identification of Z-Tyr-Ala-CHN2, a cathepsin L inhibitor with broad-spectrum cell-specific activity against coronaviruses, including SARS-CoV-2 Multifaceted roles of SAMHD1 in cancer Repurposing of the antibiotic nitroxoline for the treatment of mpox SARS-CoV-2 variants show different host cell proteome profiles with delayed immune response activation in Omicron-infected cells Increased HRD score in cisplatin resistant penile cancer cells USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING The routine use of LCD-Array hybridisation technique for HPV subtyping in the diagnosis of penile carcinoma compared to other methods Amygdalin exerts antitumor activity in taxane-resistant prostate cancer cells Bedeutung von SAMHD1 als Resistenzfaktor im humanen Neuroblastom Development and optimisation of a high-throughput screening assay for in vitro antiSARS-CoV-2 activity: evaluation of 5676 phase 1 passed structures Development and optimization of a high-throughput screening assay for in vitro anti-SARS-CoV-2 activity: Evaluation of 5676 Phase 1 Passed Structures Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform Impact of the COVID-19 pandemic on the circulation of other pathogens in England In vitro Charakterisierung von Cisplatin-resistenten Neuroblastom-Sublinien Omicron-induced interferon signalling prevents influenza A virus infection Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant SARS-CoV-2 isolates Repurposing of the antibiotic nitroxoline for the treatment of mpox SARS-CoV-2 Omicron variant virus isolates are highly sensitive to interferon treatment SARS-CoV-2 Omicron variant virus isolates are highly sensitive to interferon treatment Synergism of interferon-beta with antiviral drugs against SARS-CoV-2 variants The routine use of LCD-Array hybridisation technique for HPV subtyping in the diagnosis of penile carcinoma compared to other methods USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING Value of c-MET and Associated Signaling Elements for Predicting Outcomes and Targeted Therapy in Penile Cancer Metallodrug Profiling against SARS‐CoV‐2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain‐like Protease PL pro Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants Evaluation of stability and inactivation methods of SARS-CoV-2 in context of laboratory settings A potential role of the CD47/SIRPalpha axis in COVID-19 pathogenesis Assessment of PI3K/mTOR/AKT pathway elements to serve as biomarkers and therapeutic targets in penile cancer Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies CD47 as a potential biomarker for the early diagnosis of severe COVID-19 Characterization of ACE inhibitors and AT1R antagonists with regard to their effect on ACE2 expression and infection with SARS-CoV-2 using a Caco-2 cell model Constitutive Cell Proliferation Regulating Inhibitor of Protein Phosphatase 2A (CIP2A) Mediates Drug Resistance to Erlotinib in an EGFR Activating Mutated NSCLC Cell Line Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells Enisamium inhibits SARS-CoV-2 RNA synthesis Evaluation of stability and inactivation methods of SARS-CoV-2 in context of laboratory settings Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection Genome-scale integration of transcriptome and metabolome unveils squalene synthase and dihydrofolate reductase as targets against AML cells resistant to chemotherapy In vitro activity of itraconazole against SARS-CoV-2 Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants Infectivity of deceased COVID-19 patients Multifaceted roles of SAMHD1 in cancer Shikonin reduces growth of docetaxel-resistant prostate cancer cells mainly through necroptosis Shikonin reduces growth of docetaxel-resistant prostate cancer cells mainly through necroptosis Targeting the pentose phosphate pathway for SARS-CoV-2 therapy The COVID-19 PHARMACOME: a method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization Untersuchung synthetischer Letalität in Vincristin-resistenten Neuroblastomzellen Towards image-based cancer cell lines authentication using deep neural networks Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity Thiourea and Guanidine Compounds and Their Iridium Complexes in Drug‐Resistant Cancer Cell Lines: Structure‐Activity Relationships and Direct Luminescent Imaging Aprotinin inhibits SARS-CoV-2 replication Artesunate impairs growth in cisplatin-resistant bladder cancer cells by cell cycle arrest, apoptosis and autophagy induction Characterization of protease activity of Nsp3 from SARS-CoV-2 and its in vitro inhibition by nanobodies Charakterisierung von Neuroblastomzelllinien und ihrer platinresistenten Sublinien und Möglichkeit der Resistenzüberwindung mittels ausgewählter Substanzen der Connectivity Map COVID-19-related coagulopathy - is transferrin a missing link? COVID-19-related coagulopathy - is transferrin a missing link? Drug-adapted cancer cell lines reveal drug-induced heterogeneity and enable the identification of biomarker candidates for the acquired resistance setting

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Katalog der Deutschen Nationalbibliothek

Jindrich Cinatl

A Monoclonal Human Alveolar Epithelial Cell Line (“Arlo”) with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections

A Monoclonal Human Alveolar Epithelial Cell Line ("Arlo") with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections

Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform

Identification of Z-Tyr-Ala-CHN2, a cathepsin L inhibitor with broad-spectrum cell-specific activity against coronaviruses, including SARS-CoV-2

Multifaceted roles of SAMHD1 in cancer

Repurposing of the antibiotic nitroxoline for the treatment of mpox

SARS-CoV-2 variants show different host cell proteome profiles with delayed immune response activation in Omicron-infected cells

Increased HRD score in cisplatin resistant penile cancer cells

USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING

The routine use of LCD-Array hybridisation technique for HPV subtyping in the diagnosis of penile carcinoma compared to other methods

Amygdalin exerts antitumor activity in taxane-resistant prostate cancer cells

Bedeutung von SAMHD1 als Resistenzfaktor im humanen Neuroblastom

Development and optimisation of a high-throughput screening assay for in vitro antiSARS-CoV-2 activity: evaluation of 5676 phase 1 passed structures

Development and optimization of a high-throughput screening assay for in vitro anti-SARS-CoV-2 activity: Evaluation of 5676 Phase 1 Passed Structures

Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform

Impact of the COVID-19 pandemic on the circulation of other pathogens in England

In vitro Charakterisierung von Cisplatin-resistenten Neuroblastom-Sublinien

Omicron-induced interferon signalling prevents influenza A virus infection

Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant SARS-CoV-2 isolates

Repurposing of the antibiotic nitroxoline for the treatment of mpox

SARS-CoV-2 Omicron variant virus isolates are highly sensitive to interferon treatment

SARS-CoV-2 Omicron variant virus isolates are highly sensitive to interferon treatment

Synergism of interferon-beta with antiviral drugs against SARS-CoV-2 variants

The routine use of LCD-Array hybridisation technique for HPV subtyping in the diagnosis of penile carcinoma compared to other methods

USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING

Value of c-MET and Associated Signaling Elements for Predicting Outcomes and Targeted Therapy in Penile Cancer

Metallodrug Profiling against SARS‐CoV‐2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain‐like Protease PL pro

Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells

Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants

Evaluation of stability and inactivation methods of SARS-CoV-2 in context of laboratory settings

A potential role of the CD47/SIRPalpha axis in COVID-19 pathogenesis

Assessment of PI3K/mTOR/AKT pathway elements to serve as biomarkers and therapeutic targets in penile cancer

Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies

CD47 as a potential biomarker for the early diagnosis of severe COVID-19

Characterization of ACE inhibitors and AT1R antagonists with regard to their effect on ACE2 expression and infection with SARS-CoV-2 using a Caco-2 cell model

Constitutive Cell Proliferation Regulating Inhibitor of Protein Phosphatase 2A (CIP2A) Mediates Drug Resistance to Erlotinib in an EGFR Activating Mutated NSCLC Cell Line

Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells

Enisamium inhibits SARS-CoV-2 RNA synthesis

Evaluation of stability and inactivation methods of SARS-CoV-2 in context of laboratory settings

Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection

Genome-scale integration of transcriptome and metabolome unveils squalene synthase and dihydrofolate reductase as targets against AML cells resistant to chemotherapy

In vitro activity of itraconazole against SARS-CoV-2

Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants

Infectivity of deceased COVID-19 patients

Multifaceted roles of SAMHD1 in cancer

Shikonin reduces growth of docetaxel-resistant prostate cancer cells mainly through necroptosis

Shikonin reduces growth of docetaxel-resistant prostate cancer cells mainly through necroptosis

Targeting the pentose phosphate pathway for SARS-CoV-2 therapy

The COVID-19 PHARMACOME: a method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization

Untersuchung synthetischer Letalität in Vincristin-resistenten Neuroblastomzellen

Towards image-based cancer cell lines authentication using deep neural networks

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

Thiourea and Guanidine Compounds and Their Iridium Complexes in Drug‐Resistant Cancer Cell Lines: Structure‐Activity Relationships and Direct Luminescent Imaging

Aprotinin inhibits SARS-CoV-2 replication

Artesunate impairs growth in cisplatin-resistant bladder cancer cells by cell cycle arrest, apoptosis and autophagy induction

Characterization of protease activity of Nsp3 from SARS-CoV-2 and its in vitro inhibition by nanobodies

Charakterisierung von Neuroblastomzelllinien und ihrer platinresistenten Sublinien und Möglichkeit der Resistenzüberwindung mittels ausgewählter Substanzen der Connectivity Map

COVID-19-related coagulopathy - is transferrin a missing link?

COVID-19-related coagulopathy - is transferrin a missing link?

Drug-adapted cancer cell lines reveal drug-induced heterogeneity and enable the identification of biomarker candidates for the acquired resistance setting