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Dimitrios Tsikas

Pharmakologe

Name	Dimitrios Tsikas
Time	1987 (Wirkungsdaten)
Place	Hannover (Wirkungsort) Deutschland
Academic degree	Prof. Dr. rer. nat.
Profession	Pharmakologe (characteristic profession)
Related	Medizinische Hochschule Hannover Medizinische Hochschule Hannover. Institut für Klinische Pharmakologie
Record type	Person
GND-Identifier	130833401
Record ID	130833401
Involved in show all Drugs to affect the smooth musculature of the human ureter - an update with integrated information from basic science to the use in medical expulsion therapy (MET) Creatine homeostasis and the kidney: comparison between kidney transplant recipients and healthy controls GC–MS analysis of 4-hydroxyproline: elevated proline hydroxylation in metformin-associated lactic acidosis and metformin-treated Becker muscular dystrophy patients GC-MS-basierte Untersuchungen zur pathophysiologischen Bedeutung von post-translationalen Modifikationen von Lysin mit Fokus auf Glykation und Methylierung Amino acids, post-translational modifications, nitric oxide, and oxidative stress in serum and urine of long COVID and ex COVID human subjects Endocannabinergic modulation of central serotonergic activity in healthy human volunteers Potentiation of Lipotoxicity in Human EndoC‐βH1 β‐Cells by Glucose is Dependent on the Structure of Free Fatty Acids Effects of Short-Term Sodium Nitrate versus Sodium Chloride Supplementation on Energy and Lipid Metabolism during High-Intensity Intermittent Exercise in Athletes Possible role of SIRT1 and SIRT3 in post-translational modifications in human breast milk during the neonatal period N-Acetyl-L-cysteine in human rheumatoid arthritis and its effects on nitric oxide (NO) and malondialdehyde (MDA): analytical and clinical considerations Lysine and homoarginine are closely interrelated metabolites in the rat Specific and sensitive GC–MS analysis of hypusine, N ε-(4-amino-2-hydroxybutyl)lysine, a biomarker of hypusinated eukaryotic initiation factor eIF5A, and its application to the bi-ethnic ASOS study Short-Term Supplementation of Sodium Nitrate vs. Sodium Chloride Increases Homoarginine Synthesis in Young Men Independent of Exercise Urinary excretion of amino acids and their advanced glycation end-products (AGEs) in adult kidney transplant recipients with emphasis on lysine: furosine excretion is associated with cardiovascular and all-cause mortality Development, validation of a GC–MS method for the simultaneous measurement of amino acids, their PTM metabolites and AGEs in human urine, and application to the bi-ethnic ASOS study with special emphasis to lysine Profile of urinary amino acids and their post-translational modifications (PTM) including advanced glycation end-products (AGEs) of lysine, arginine and cysteine in lean and obese ZSF1 rats Homocysteine and copper ions: is their interaction responsible for cardiovascular-related damage? Whole-body arginine dimethylation is associated with all-cause mortality in adult renal transplant recipients Extra-platelet low-molecular-mass thiols mediate the inhibitory action of S-nitrosoalbumin on human platelet aggregation via S-transnitrosylation of the platelet surface Central systolic blood pressure relates inversely to nitric oxide synthesis in young black adults: the African-PREDICT study Urinary albumin-to-creatinine ratio is inversely related to nitric oxide synthesis in young black adults: the African-PREDICT study Nitric oxide-related markers link inversely to blood pressure in black boys and men: the ASOS and African-PREDICT studies Activated L-arginine/nitric oxide pathway in pediatric cystic fibrosis and its association with pancreatic insufficiency, liver involvement and nourishment : an overview and new results Enhanced nitric oxide (NO) and decreased ADMA synthesis in pediatric ADHD and selective potentiation of NO synthesis by methylphenidate Local and systemic alterations of the L-arginine/nitric oxide pathway in sputum, blood, and urine of pediatric cystic fibrosis patients and effects of antibiotic treatment Massenspektrometrie-basierte in vitro und in vivo Studien zu posttranslationalen Modifikationen von Arginin und Bestimmung der Ganzkörper-Arginin-Dimethylierung am Menschen Urinary Taurine Excretion and Risk of Late Graft Failure in Renal Transplant Recipients Asymmetric dimethylation and citrullination in the LEW.1AR1-iddm rat, an animal model of human type 1 diabetes, and effects of anti-TCR/anti-TNF-α antibody-based therapy Synthesis of homoagmatine and GC–MS analysis of tissue homoagmatine and agmatine: evidence that homoagmatine but not agmatine is a metabolite of pharmacological L-homoarginine in the anesthetized rat GC–MS measurement of spermidine and putrescine in serum of elderly subjects: intriguing association between spermidine and homoarginine High plasma guanidinoacetate-to-homoarginine ratio is associated with high all-cause and cardiovascular mortality rate in adult renal transplant recipients Emerging drugs to target lower urinary tract symptomatology (LUTS)/benign prostatic hyperplasia (BPH): focus on the prostate Distinct associations between plasma osteoprotegerin, homoarginine and asymmetric dimethylarginine in chronic kidney disease male patients with coronary artery disease Asymmetric dimethylation and citrullination of proteinic arginine and homoarginine synthesis in human Helicobacter pylori infection Plasma ADMA, urinary ADMA excretion, and late mortality in renal transplant recipients GC–MS measurement of biological N G-hydroxy-l-arginine, a stepmotherly investigated endogenous nitric oxide synthase substrate and arginase inhibitor Effect of renal function on homeostasis of asymmetric dimethylarginine (ADMA): studies in donors and recipients of renal transplants Development and validation of GC–MS methods for the comprehensive analysis of amino acids in plasma and urine and applications to the HELLP syndrome and pediatric kidney transplantation: evidence of altered methylation, transamidination, and arginase activity Exercise-induced oxidative stress, nitric oxide and plasma amino acid profile in recreational runners with vegetarian and non-vegetarian dietary patterns Site-specific intracellular generation and detection of hydrogen peroxide and protection against oxidative stress in insulin-producing cells Pharmacological activation of dimethylarginine dimethylaminohydrolase (DDAH) activity by inorganic nitrate and DDAH inhibition by N G-hydroxy-l-arginine, N ω,N ω-dimethyl-l-citrulline and N ω,N ω-dimethyl-N δ-hydroxy-l-citrulline: results and overview Effects of single and combined metformin and l-citrulline supplementation on l-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and homoarginine (hArg): the ADMA, SDMA and hArg paradoxes Inverse correlation between maternal plasma asymmetric dimethylarginine (ADMA) and birthweight percentile in women with impaired placental perfusion: circulating ADMA as an NO-independent indicator of fetal growth restriction? Metabolism and distribution of pharmacological homoarginine in plasma and main organs of the anesthetized rat Low plasma homoarginine concentration is associated with high rates of all-cause mortality in renal transplant recipients The role of l-arginine/l-homoarginine/nitric oxide pathway for aortic distensibility and intima-media thickness in stroke patients Comprehensive analysis of the l-arginine/l-homoarginine/nitric oxide pathway in preterm neonates: potential roles for homoarginine and asymmetric dimethylarginine in foetal growth Carbonic anhydrases are producers of S-nitrosothiols from inorganic nitrite and modulators of soluble guanylyl cyclase in human platelets Untersuchung von Arzneimittelrückständen im Abwasser der Stadt Dresden High urinary homoarginine excretion is associated with low rates of all-cause mortality and graft failure in renal transplant recipients Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free l-arginine in humans Entwicklung und Etablierung eines Modells zur Bestimmung des oxidativen/nitrativen Stresses in vivo am Menschen auf der Basis der Nitrierung von oral verabreichtem Paracetamol In-vitro-Metabolismus des neuen lipophilen und Zellmembranen-permeablen NO-Donors S-Nitroso-N-Acetylcystein-Ethylester (SNACET) in Humanblut : mögliche Konsequenzen für pharmakokinetische Untersuchungen zu SNACET Entwicklung, Validierung und Anwendung einer HPLC-Methode zur Untersuchung der Nitrit-induzierten Oxidation von Glutathion (GSH) und Oxyhämoglobin in Human-Erythrozyten Developmental changes in the L-arginine/nitric oxide pathway from infancy to adulthood: plasma asymmetric dimethylarginine levels decrease with age Festschrift on the occasion of the 65th birthday of Professor Jürgen C. Frölich : [vascular NO: from bench to bedside ; an international symposium, Hannover, Germany, March 11 - 13, 2004] Asymmetric dimethylarginine (ADMA) and the risk for coronary heart disease: the multicenter CARDIAC study Circulating and excretory nitrite and nitrate as indicators of nitric oxide synthesis in humans: methods of analysis

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Katalog der Deutschen Nationalbibliothek

Dimitrios Tsikas

Drugs to affect the smooth musculature of the human ureter - an update with integrated information from basic science to the use in medical expulsion therapy (MET)

Creatine homeostasis and the kidney: comparison between kidney transplant recipients and healthy controls

GC–MS analysis of 4-hydroxyproline: elevated proline hydroxylation in metformin-associated lactic acidosis and metformin-treated Becker muscular dystrophy patients

GC-MS-basierte Untersuchungen zur pathophysiologischen Bedeutung von post-translationalen Modifikationen von Lysin mit Fokus auf Glykation und Methylierung

Amino acids, post-translational modifications, nitric oxide, and oxidative stress in serum and urine of long COVID and ex COVID human subjects

Endocannabinergic modulation of central serotonergic activity in healthy human volunteers

Potentiation of Lipotoxicity in Human EndoC‐βH1 β‐Cells by Glucose is Dependent on the Structure of Free Fatty Acids

Effects of Short-Term Sodium Nitrate versus Sodium Chloride Supplementation on Energy and Lipid Metabolism during High-Intensity Intermittent Exercise in Athletes

Possible role of SIRT1 and SIRT3 in post-translational modifications in human breast milk during the neonatal period

N-Acetyl-L-cysteine in human rheumatoid arthritis and its effects on nitric oxide (NO) and malondialdehyde (MDA): analytical and clinical considerations

Lysine and homoarginine are closely interrelated metabolites in the rat

Specific and sensitive GC–MS analysis of hypusine, N ε-(4-amino-2-hydroxybutyl)lysine, a biomarker of hypusinated eukaryotic initiation factor eIF5A, and its application to the bi-ethnic ASOS study

Short-Term Supplementation of Sodium Nitrate vs. Sodium Chloride Increases Homoarginine Synthesis in Young Men Independent of Exercise

Urinary excretion of amino acids and their advanced glycation end-products (AGEs) in adult kidney transplant recipients with emphasis on lysine: furosine excretion is associated with cardiovascular and all-cause mortality

Development, validation of a GC–MS method for the simultaneous measurement of amino acids, their PTM metabolites and AGEs in human urine, and application to the bi-ethnic ASOS study with special emphasis to lysine

Profile of urinary amino acids and their post-translational modifications (PTM) including advanced glycation end-products (AGEs) of lysine, arginine and cysteine in lean and obese ZSF1 rats

Homocysteine and copper ions: is their interaction responsible for cardiovascular-related damage?

Whole-body arginine dimethylation is associated with all-cause mortality in adult renal transplant recipients

Extra-platelet low-molecular-mass thiols mediate the inhibitory action of S-nitrosoalbumin on human platelet aggregation via S-transnitrosylation of the platelet surface

Central systolic blood pressure relates inversely to nitric oxide synthesis in young black adults: the African-PREDICT study

Urinary albumin-to-creatinine ratio is inversely related to nitric oxide synthesis in young black adults: the African-PREDICT study

Nitric oxide-related markers link inversely to blood pressure in black boys and men: the ASOS and African-PREDICT studies

Activated L-arginine/nitric oxide pathway in pediatric cystic fibrosis and its association with pancreatic insufficiency, liver involvement and nourishment : an overview and new results

Enhanced nitric oxide (NO) and decreased ADMA synthesis in pediatric ADHD and selective potentiation of NO synthesis by methylphenidate

Local and systemic alterations of the L-arginine/nitric oxide pathway in sputum, blood, and urine of pediatric cystic fibrosis patients and effects of antibiotic treatment

Massenspektrometrie-basierte in vitro und in vivo Studien zu posttranslationalen Modifikationen von Arginin und Bestimmung der Ganzkörper-Arginin-Dimethylierung am Menschen

Urinary Taurine Excretion and Risk of Late Graft Failure in Renal Transplant Recipients

Asymmetric dimethylation and citrullination in the LEW.1AR1-iddm rat, an animal model of human type 1 diabetes, and effects of anti-TCR/anti-TNF-α antibody-based therapy

Synthesis of homoagmatine and GC–MS analysis of tissue homoagmatine and agmatine: evidence that homoagmatine but not agmatine is a metabolite of pharmacological L-homoarginine in the anesthetized rat

GC–MS measurement of spermidine and putrescine in serum of elderly subjects: intriguing association between spermidine and homoarginine

High plasma guanidinoacetate-to-homoarginine ratio is associated with high all-cause and cardiovascular mortality rate in adult renal transplant recipients

Emerging drugs to target lower urinary tract symptomatology (LUTS)/benign prostatic hyperplasia (BPH): focus on the prostate

Distinct associations between plasma osteoprotegerin, homoarginine and asymmetric dimethylarginine in chronic kidney disease male patients with coronary artery disease

Asymmetric dimethylation and citrullination of proteinic arginine and homoarginine synthesis in human Helicobacter pylori infection

Plasma ADMA, urinary ADMA excretion, and late mortality in renal transplant recipients

GC–MS measurement of biological N G-hydroxy-l-arginine, a stepmotherly investigated endogenous nitric oxide synthase substrate and arginase inhibitor

Effect of renal function on homeostasis of asymmetric dimethylarginine (ADMA): studies in donors and recipients of renal transplants

Development and validation of GC–MS methods for the comprehensive analysis of amino acids in plasma and urine and applications to the HELLP syndrome and pediatric kidney transplantation: evidence of altered methylation, transamidination, and arginase activity

Exercise-induced oxidative stress, nitric oxide and plasma amino acid profile in recreational runners with vegetarian and non-vegetarian dietary patterns

Site-specific intracellular generation and detection of hydrogen peroxide and protection against oxidative stress in insulin-producing cells

Pharmacological activation of dimethylarginine dimethylaminohydrolase (DDAH) activity by inorganic nitrate and DDAH inhibition by N G-hydroxy-l-arginine, N ω,N ω-dimethyl-l-citrulline and N ω,N ω-dimethyl-N δ-hydroxy-l-citrulline: results and overview

Effects of single and combined metformin and l-citrulline supplementation on l-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications

Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings

Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and homoarginine (hArg): the ADMA, SDMA and hArg paradoxes

Inverse correlation between maternal plasma asymmetric dimethylarginine (ADMA) and birthweight percentile in women with impaired placental perfusion: circulating ADMA as an NO-independent indicator of fetal growth restriction?

Metabolism and distribution of pharmacological homoarginine in plasma and main organs of the anesthetized rat

Low plasma homoarginine concentration is associated with high rates of all-cause mortality in renal transplant recipients

The role of l-arginine/l-homoarginine/nitric oxide pathway for aortic distensibility and intima-media thickness in stroke patients

Comprehensive analysis of the l-arginine/l-homoarginine/nitric oxide pathway in preterm neonates: potential roles for homoarginine and asymmetric dimethylarginine in foetal growth

Carbonic anhydrases are producers of S-nitrosothiols from inorganic nitrite and modulators of soluble guanylyl cyclase in human platelets

Untersuchung von Arzneimittelrückständen im Abwasser der Stadt Dresden

High urinary homoarginine excretion is associated with low rates of all-cause mortality and graft failure in renal transplant recipients

Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free l-arginine in humans

Entwicklung und Etablierung eines Modells zur Bestimmung des oxidativen/nitrativen Stresses in vivo am Menschen auf der Basis der Nitrierung von oral verabreichtem Paracetamol

In-vitro-Metabolismus des neuen lipophilen und Zellmembranen-permeablen NO-Donors S-Nitroso-N-Acetylcystein-Ethylester (SNACET) in Humanblut : mögliche Konsequenzen für pharmakokinetische Untersuchungen zu SNACET

Entwicklung, Validierung und Anwendung einer HPLC-Methode zur Untersuchung der Nitrit-induzierten Oxidation von Glutathion (GSH) und Oxyhämoglobin in Human-Erythrozyten

Developmental changes in the L-arginine/nitric oxide pathway from infancy to adulthood: plasma asymmetric dimethylarginine levels decrease with age

Festschrift on the occasion of the 65th birthday of Professor Jürgen C. Frölich : [vascular NO: from bench to bedside ; an international symposium, Hannover, Germany, March 11 - 13, 2004]

Asymmetric dimethylarginine (ADMA) and the risk for coronary heart disease: the multicenter CARDIAC study

Circulating and excretory nitrite and nitrate as indicators of nitric oxide synthesis in humans: methods of analysis