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The EBMT Handbook : Hematopoietic Cell Transplantation and Cellular Therapies / edited by Anna Sureda, Selim Corbacioglu, Raffaella Greco, Nicolaus Kröger, Enric Carreras

Cham: Springer International Publishing, Imprint: Springer
2024

8th ed. 2024

Online-Ressource, XL, 862 p. 62 illus., 47 illus. in color. : online resource.

Part I . Introduction -- 1. HCT: Historical Perspective -- 2. The EBMT: History, Present, and Future -- 3. Registries – a bridge between donor and recipient -- 4. The HCT Unit -- 5. JACIE Accreditation of HCT Programs -- 6. Statistical Methods in HCT and Cellular Therapies -- Part II . Biological Aspects -- 7. Biological Properties Of Hematopoietic Stem Cells: Scientific Basis For Hematopoietic Cell Transplantation -- 8. Biological Properties of Cells Other Than HSCs -- 9. Histocompatibility -- 10. Clinical and biological concepts for mastering immune reconstitution after hematopoietic cell transplantation: towards practical guidelines and greater harmonization -- Part III . Methodology and Clinical Aspects -- 11. Evaluation and Counseling of Candidates -- 12. Donor Selection for Adults and Pediatrics -- 13. Conditioning -- 14. Selection of stem cell source -- 15. Bone Marrow Harvesting for HCT -- 16. Mobilization and Collection of HSC -- 17. Mobilization and Collection of HSC in Children -- 18. Procurement and Management of Cord Blood Unit for allogeneic transplantation -- 19. Graft Manipulation -- 20. Processing, Cryopreserving and Controlling the Quality of HSC -- 21. Documentation of Engraftment and Chimerism After HCT -- 22. Short- and Long-Term Controls After HCT -- Part IV . General Management of the Patient -- 23. Vascular Access -- 24. Transfusion Support -- 25. Nutritional Support -- 26. GVHD Prophylaxis -- 27. Infection Control and Isolation Procedures -- 28. General Management of the Patient: Specific Aspects of Infectious Disease Supportive Care in Children -- 29. Vaccinations -- 30. Psychological Morbidity and Care -- 31. Clinically Relevant Drug Interactions in HCT -- 32. The Roles of the HCT Nurse -- 33. Ethical Issues in HCT -- 34. Quality of Life Assessment After HCT for Pediatric and Adults -- Part V. HCT Complications and Management -- 35. Neutropenic Fever -- 36. Bacterial Infections -- 37. Invasive fungal diseases -- 38. Viral Infections -- 39. Other Life-Threatening Infections -- 40. Bleeding and Thrombotic Complications -- 41. Graft Failure -- 42. Early complications of endothelial origin -- 43. Acute Graft-Versus-Host Disease -- 44. Chronic Graft-Versus-Host Disease -- 45. Post-transplant lymphoproliferative syndromes -- 46. Iron Overload -- 47. Secondary Neoplasia (Other than PTLPS) -- Part VI . Specific Organ Complications -- 48. Ocular and Oral Complications -- 49. Hepatic complications -- 50. Gastrointestinal Complications -- 51. Haemorrhagic Cystitis and Renal Dysfunction -- 52. Noninfectious Pulmonary Complications -- 53. Neurological Complications -- 54. Skin, Hair and Musculoskeletal Complications -- 55. Cardiovascular Diseases and Metabolic Syndrome -- 56. Endocrine Disorders, Fertility and Sexual Health -- Part VII . Prevention and Management of Relapse -- 57. Monitoring Measurable Residual Disease in ALL and AML -- 58. Prevention and Treatment of Relapse by Drugs -- 59. Delayed transfer of immune cells, or the art of donor lymphocyte infusion (DLI) 2.0 -- 60. Cellular Therapy with Engineered T Cells, Efficacy and Side Effects: Gene Editing/Gene Therapy -- 61. Mechanisms of Immune Resistance -- 62. Regulatory Aspects Of Atmp Versus Minimally Manipulated Immune Cells -- Part VIII . Specific Modalities of HCT and Management -- 63. At Home HCT -- 64. Role Of Umbilical Cord Blood Transplantation -- 65. Haploidentical HCT -- 66. Photopheresis in Adults and Pediatrics -- 67. Overweight and obese patients -- 68. HCT in Elderly Patients -- 69. Feasibility and Experiences of HCT in Resource-constrained Settings -- Part IX . Indications and Results -- 70. AML in adults -- 71. Acute Myeloid Leukemia in Children -- 72. Acute Lymphoblastic Leukemia in Adults -- 73. Acute Lymphoblastic Leukemia in Children and Adolescents -- 74. Myelodysplastic Neoplasms/Syndromes (MDS) -- 75. Allogeneic hematopoietic cell transplantation in pediatric MDS including refractory cytopenia of childhood and in juvenile myelomonocytic leukemia -- 76. Myelodysplastic/Myeloproliferative Neoplasms -- 77. Myeloproliferative Neoplasms -- 78. Acquired bone marrow failure: Severe Aplastic Anemia and Paroxysmal nocturnal hemoglobinuria -- 79. Fanconi Anemia and Other Hereditary Bone Marrow Failure Syndromes -- 80. Hemoglobinopathies (Sickle Cell Disease and Thalassemia) -- 81. Multiple Myeloma -- 82. Systemic Light Chain Amyloidosis -- 83. Poems Syndrome And Disease Produced By Other Monoclonal IGS -- 84. Indolent Lymphoma -- 85. CHRONIC LYMPHOCYTIC LEUKEMIA -- 86. Large B-Cell Lymphoma -- 87. Mantle Cell Lymphoma -- 88. Other B- and T-Aggressive Lymphomas & Lymphomas Associated with HIV -- 89. Classical Hodgkin’s Lymphoma -- 90. Inborn errors of immunity -- 91. Inborn Errors of Metabolism and Osteopetrosis -- 92. Autoimmune Disease -- 93. CART cells & other cell therapies (ie MSC, Tregs) in autoimmune diseases -- 94. Solid Tumours

978-3-031-44080-9

Englisch

Deutschland

Medizin, Gesundheit

Hematology.
Transplantation.
Internal Medicine.
Pediatric Surgery.
Cancer Therapy.

616.027

urn:nbn:de:101:1-2024041104184745812946 (URN)
10.1007/978-3-031-44080-9 (DOI)

1325802948