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Olaf Groß (1976-)

Name	Olaf Groß
Time	1976- (Date of birth and death)
Place	Biedenkopf (Geburtsort) Deutschland
Gender	männlich
Academic degree	Dr. rer. nat. (am Lehrstuhl für Entwicklungsgenetik der TU München) (2008)
Further information	Habil.-Schr. im Fach Molekulare Medizin an der Medizinischen Fakultät der TU München, 2014
Source	AM Metadaten
Record type	Person
GND-Identifier	13556591X
Record ID	13556591X
Involved in show all Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations IL-6 trans-signaling: an overlooked driver of retinal neovascularization? Oncostatin M induced by STAT5-activating oncogenes promotes disease progression in hematologic malignancies Downregulation of TCF19 and ATAD2 causes endothelial cell cycle arrest at the transition from cardiac hypertrophy to heart failure NLRP3 mediates lipid-driven macrophage proliferation in established atherosclerosis Synthesis and Evaluation of Trehalose‐Based Mertansine Warheads for Bacillus Calmette–Guérin Delivery of Anticancer Agents Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation Downregulation of TCF19 and ATAD2 causes endothelial cell cycle arrest at the transition from cardiac hypertrophy to heart failure Externalized inflammasomes in visceral fat sustain obesity-related inflammation Identifying biomedical entities for datasets in scientific articles: 4-step cache-augmented generation approach using gpt-4o and pubtator 3.0 IL-6 trans-signaling: an overlooked driver of retinal neovascularization? Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease NLRP3 mediates lipid-driven macrophage proliferation in established atherosclerosis Oncostatin M induced by STAT5-activating oncogenes promotes disease progression in hematologic malignancies Synthesis and evaluation of trehalose-based mertansine warheads for Bacillus Calmette-Guérin delivery of anticancer agents A new silicon phthalocyanine dye induces pyroptosis in prostate cancer cells during photoimmunotherapy ADP-ribosylation factor-interacting protein 2 acts as a novel regulator of mitophagy and autophagy in podocytes in diabetic nephropathy Distinct sequential death complexes regulate pyroptosis and IL-1β release in response to Yersinia blockade of immune signaling = Distinct sequential death complexes regulate pyroptosis and IL-1[beta] release in response to Yersinia blockade of immune signaling DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress Dynamic modelling of signalling pathways when ODEs are not feasible Molecular mechanisms underlying NLRP3 inflammasome activation and IL-1β production in air pollution fine particulate matter (PM2.5)-primed macrophages Single-cell deconvolution reveals high lineage- and location-dependent heterogeneity in mesenchymal multivisceral stage IV colorectal cancer Size exclusion chromatography based proteomic and degradomic profiling of inflammasome-activated, murine bone marrow-derived dendritic cells highlights complex retention and release of cleavage products The tumour-promoting role of ZBTB18 N-terminal short form in glioblastoma progression and initial characterization of ZBTB18 C-terminal short form Development of first-in-class dual Sirt2/HDAC6 inhibitors as molecular tools for dual inhibition of tubulin deacetylation Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+T cells Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation Modification of dietary substrates impacts glucose homeostasis in very long-chain Acyl-CoA dehydrogenase deficient (VLCAD-/-) mice SPATA2 regulates inflammation and cell death independently of CYLD SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD The impact of metabolic stressors on mitochondrial homeostasis in a renal epithelial cell model of methylmalonic aciduria Tissue imprinting defines a functional mosaic of dermal macrophages β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner = [Beta]-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner Chemoproteomik‐basierte Identifikation von 4‐Oxo‐β‐lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9 Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9 Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9 Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9 Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia Paradoxical immunodeficiencies—When failures of innate immunity cause immunopathology An improved organotypic cell culture system to study tissue-resident macrophages ex vivo Chemoproteomics‐enabled identification of 4‐Oxo‐β‐lactams as inhibitors of dipeptidyl peptidases 8 and 9 Chemoproteomik‐basierte Identifikation von 4‐Oxo‐β‐lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9 = Chemoproteomik‐basierte Identifikation von 4‐Oxo‐[beta]‐lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9 Distinct regulatory pathways controlling NLRP3 inflammasome in infectious and non-infectious diseases Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia Interleukin-1[beta] suppression dampens inflammatory leukocyte production and uptake in atherosclerosis Paradoxical immunodeficiencies - when failures of innate immunity cause immunopathology Cardiomyocyte‐specific miR‐100 overexpression preserves heart function under pressure overload in mice and diminishes fatty acid uptake as well as ROS production by direct suppression of Nox4 and CD36 Lack of electron acceptors contributes to redox stress and growth arrest in asparagine-starved sarcoma cells Piezo1 channels contribute to the regulation of human atrial fibroblast mechanical properties and matrix stiffness sensing Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile Immune modulatory effects of oncogenic KRAS in cancer Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation Walking over the inflammasome The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes Toll-like receptor 7/8 agonists stimulate plasmacytoid dendritic cells to initiate TH17-deviated acute contact dermatitis in human subjects Specific surface modifications of silica nanoparticles diminish inflammasome activation and in vivo expression of selected inflammatory genes

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Katalog der Deutschen Nationalbibliothek

Olaf Groß (1976-)

Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations

Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface

Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations

IL-6 trans-signaling: an overlooked driver of retinal neovascularization?

Oncostatin M induced by STAT5-activating oncogenes promotes disease progression in hematologic malignancies

Downregulation of TCF19 and ATAD2 causes endothelial cell cycle arrest at the transition from cardiac hypertrophy to heart failure

NLRP3 mediates lipid-driven macrophage proliferation in established atherosclerosis

Synthesis and Evaluation of Trehalose‐Based Mertansine Warheads for Bacillus Calmette–Guérin Delivery of Anticancer Agents

Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation

Downregulation of TCF19 and ATAD2 causes endothelial cell cycle arrest at the transition from cardiac hypertrophy to heart failure

Externalized inflammasomes in visceral fat sustain obesity-related inflammation

Identifying biomedical entities for datasets in scientific articles: 4-step cache-augmented generation approach using gpt-4o and pubtator 3.0

IL-6 trans-signaling: an overlooked driver of retinal neovascularization?

Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease

NLRP3 mediates lipid-driven macrophage proliferation in established atherosclerosis

Oncostatin M induced by STAT5-activating oncogenes promotes disease progression in hematologic malignancies

Synthesis and evaluation of trehalose-based mertansine warheads for Bacillus Calmette-Guérin delivery of anticancer agents

A new silicon phthalocyanine dye induces pyroptosis in prostate cancer cells during photoimmunotherapy

ADP-ribosylation factor-interacting protein 2 acts as a novel regulator of mitophagy and autophagy in podocytes in diabetic nephropathy

Distinct sequential death complexes regulate pyroptosis and IL-1β release in response to Yersinia blockade of immune signaling = Distinct sequential death complexes regulate pyroptosis and IL-1[beta] release in response to Yersinia blockade of immune signaling

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Dynamic modelling of signalling pathways when ODEs are not feasible

Molecular mechanisms underlying NLRP3 inflammasome activation and IL-1β production in air pollution fine particulate matter (PM2.5)-primed macrophages

Single-cell deconvolution reveals high lineage- and location-dependent heterogeneity in mesenchymal multivisceral stage IV colorectal cancer

Size exclusion chromatography based proteomic and degradomic profiling of inflammasome-activated, murine bone marrow-derived dendritic cells highlights complex retention and release of cleavage products

The tumour-promoting role of ZBTB18 N-terminal short form in glioblastoma progression and initial characterization of ZBTB18 C-terminal short form

Development of first-in-class dual Sirt2/HDAC6 inhibitors as molecular tools for dual inhibition of tubulin deacetylation

Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+T cells

Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation

Modification of dietary substrates impacts glucose homeostasis in very long-chain Acyl-CoA dehydrogenase deficient (VLCAD-/-) mice

SPATA2 regulates inflammation and cell death independently of CYLD

SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD

The impact of metabolic stressors on mitochondrial homeostasis in a renal epithelial cell model of methylmalonic aciduria

Tissue imprinting defines a functional mosaic of dermal macrophages

β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner = [Beta]-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner

Chemoproteomik‐basierte Identifikation von 4‐Oxo‐β‐lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9

Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9

Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9

Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9

Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia

Paradoxical immunodeficiencies—When failures of innate immunity cause immunopathology

An improved organotypic cell culture system to study tissue-resident macrophages ex vivo

Chemoproteomics‐enabled identification of 4‐Oxo‐β‐lactams as inhibitors of dipeptidyl peptidases 8 and 9

Chemoproteomik‐basierte Identifikation von 4‐Oxo‐β‐lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9 = Chemoproteomik‐basierte Identifikation von 4‐Oxo‐[beta]‐lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9

Distinct regulatory pathways controlling NLRP3 inflammasome in infectious and non-infectious diseases

Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia

Interleukin-1[beta] suppression dampens inflammatory leukocyte production and uptake in atherosclerosis

Paradoxical immunodeficiencies - when failures of innate immunity cause immunopathology

Cardiomyocyte‐specific miR‐100 overexpression preserves heart function under pressure overload in mice and diminishes fatty acid uptake as well as ROS production by direct suppression of Nox4 and CD36

Lack of electron acceptors contributes to redox stress and growth arrest in asparagine-starved sarcoma cells

Piezo1 channels contribute to the regulation of human atrial fibroblast mechanical properties and matrix stiffness sensing

Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile

Immune modulatory effects of oncogenic KRAS in cancer

Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila

Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation

Walking over the inflammasome

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

Toll-like receptor 7/8 agonists stimulate plasmacytoid dendritic cells to initiate TH17-deviated acute contact dermatitis in human subjects

Specific surface modifications of silica nanoparticles diminish inflammasome activation and in vivo expression of selected inflammatory genes