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Jennifer Nina Andexer (1980-)

Biochemikerin

Name	Jennifer Nina Andexer
Time	1980- (Date of birth and death)
Place	Haan (Geburtsort) Freiburg im Breisgau (Wirkungsort) Deutschland
Academic degree	Jun.-Prof. Dr.
Profession	Biochemikerin (characteristic profession)
Variant	Jennifer Andexer Jennifer N. Andexer
Related	Albert-Ludwigs-Universität Freiburg. Pharmazeutische und Medizinische Chemie (2011-)
Further information	Diss. Fachbereich Biologie, Heinrich-Heine Universität Düsseldorf, Institut für Molekulare Enzymtechnologie (IMET) Juniorprofessorin am Institut für Pharmazeutische Wissenschaften, Lehrstuhl für Pharmazeutische und Medizinische Chemie, Freiburg
Record type	Person
GND-Identifier	13633105X
Record ID	13633105X
Involved in show all Rewiring Escherichia coli to transform formate into methyl groups Structural Insights into Broad‐Range Polyphosphate Kinase 2‐II Enzymes Applicable for Pyrimidine Nucleoside Diphosphate Synthesis Chemoselectivity of O- and N-Methyltransferases Dinucleoside polyphosphates in cellular signaling: function and evolution across life Doping in vivo alkylation in E. coli by introducing the direct sulfurylation pathway of S. cerevisiae How to tell an N from an O: controlling the chemoselectivity of methyltransferases In vitro characterization of the aromatic SAM-dependent C-methyltransferase NapB5 Inorganic polyphosphate: a chemical biology toolbox for an underexplored biopolymer Rewiring Escherichia coli to transform formate into methyl groups Structural insights into broad‐range polyphosphate kinase 2‐II enzymes applicable for pyrimidine nucleoside diphosphate synthesis Doping In Vivo Alkylation in E. coli by Introducing the Direct Sulfurylation Pathway of S. cerevisiae Doping In Vivo Alkylation in E. coli by Introducing the Direct Sulfurylation Pathway of S. cerevisiae Structures and Protein Engineering of the α‐Keto Acid C‐Methyltransferases SgvM and MrsA for Rational Substrate Transfer Enzymatic S‐methylation of thiols catalyzed by different O‐methyltransferases New inositol pyrophosphate prometabolites: specific organelle targeting, tissue penetration, and stable isotope labelling Nuclear actin assembly is required for chromatin reorganization after mitosis as well as androgen receptor signaling Structure, function and substrate preferences of archaeal S-adenosyl-l-homocysteine hydrolases Structures and protein engineering of the [alpha]‐keto acid C‐methyltransferases SgvM and MrsA for rational substrate transfer Enzymatic S ‐Methylation of Thiols Catalyzed by Different O ‐Methyltransferases Expanding the Substrate Scope of N ‐ and O ‐Methyltransferases from Plants for Chemoselective Alkylation Enzymatic Synthesis of l ‐Methionine Analogues and Application in a Methyltransferase Catalysed Alkylation Cascade Biomimetic S ‐Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes Biomimetic S-adenosylmethionine regeneration starting from multiple byproducts enables biocatalytic alkylation with radical sam enzymes Enzymatic synthesis of l‐methionine analogues and application in a methyltransferase catalysed alkylation cascade Expanding the substrate scope of N‐ and O‐methyltransferases from plants for chemoselective alkylation Funktionelle Charakterisierung der cobalaminabhängigen Radical SAM Methyltransferase QCMT aus Methanoculleus thermophilus Modifying the makers: release factor hydroxylation, non-canonical nucleosides, and their influence on translation Non‐canonical nucleosides: biomimetic triphosphorylation, incorporation into mRNA and effects on translation and structure Targeting the deacylases SmSirt2 and hSirt2: inhibitors discovery and optimization Using the CovPDB database as a basis for the HyperCys machine learning algorithm to simplify covalent drug design Biosynthesis of Menaquinone in E. coli: Identification of an Elusive Isomer of SEPHCHC Methyltransferases: Functions and Applications A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique C α ‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique C α ‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase Photoaffinity Capture Compounds to Profile the Magic Spot Nucleotide Interactomes Photoaffinity Capture Compounds to Profile the Magic Spot Nucleotide Interactomes A cobalamin‐dependent radical sam enzyme catalyzes the unique cα‐methylation of glutamine in methyl‐coenzyme m reductase A cobalamin‐dependent radical SAM enzyme catalyzes the unique Cα‐methylation of glutamine in methyl‐coenzyme M reductase Biosynthesis of menaquinone in E. coli: identification of an elusive isomer of SEPHCHC Characterisation of family 2 polyphosphate kinases Make or break: the thermodynamic equilibrium of polyphosphate kinase-catalysed reactions Methyltransferases : : functions and applications Photoaffinity capture compounds to profile the magic spot nucleotide interactomes Photoaffinity capture compounds to profile the magic spot nucleotide interactomes** Multienzyme One‐Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids Multienzyme One‐Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids A bicyclic S-adenosylmethionine regenerationsystem applicable with different nucleosidesor nucleotides as cofactor building blocks A multi-enzyme cascade reaction for the production of 2′3′-cGAMP Biosynthesis and utilisation of PRPP and application to a cofactor regeneration system Chorismate- and isochorismate converting enzymes: versatile catalysts acting on an important metabolic node Multienzyme one‐pot cascades incorporating methyltransferases for the strategic diversification of tetrahydroisoquinoline alkaloids Multienzyme one‐pot cascades incorporating methyltransferases for the strategic diversification of tetrahydroisoquinoline alkaloids S-Adenosylhomocysteine hydrolase as a bottleneck in the biomimetic regeneration cycle of S-adenosylmethionine and its analogues Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases Channeling C1 metabolism toward S-adenosylmethionine-dependent conversion of estrogens to androgens in estrogen-degrading bacteria Single-step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases Several Polyphosphate Kinase 2 Enzymes Catalyse the Production of Adenosine 5′‐Polyphosphates A Flexible Polyphosphate‐Driven Regeneration System for Coenzyme A Dependent Catalysis Catalytic Alkylation Using a Cyclic S ‐Adenosylmethionine Regeneration System Asymmetric C‐Alkylation by the S ‐Adenosylmethionine‐Dependent Methyltransferase SgvM

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Jennifer Nina Andexer (1980-)

Rewiring Escherichia coli to transform formate into methyl groups

Structural Insights into Broad‐Range Polyphosphate Kinase 2‐II Enzymes Applicable for Pyrimidine Nucleoside Diphosphate Synthesis

Chemoselectivity of O- and N-Methyltransferases

Dinucleoside polyphosphates in cellular signaling: function and evolution across life

Doping in vivo alkylation in E. coli by introducing the direct sulfurylation pathway of S. cerevisiae

How to tell an N from an O: controlling the chemoselectivity of methyltransferases

In vitro characterization of the aromatic SAM-dependent C-methyltransferase NapB5

Inorganic polyphosphate: a chemical biology toolbox for an underexplored biopolymer

Rewiring Escherichia coli to transform formate into methyl groups

Structural insights into broad‐range polyphosphate kinase 2‐II enzymes applicable for pyrimidine nucleoside diphosphate synthesis

Doping In Vivo Alkylation in E. coli by Introducing the Direct Sulfurylation Pathway of S. cerevisiae

Doping In Vivo Alkylation in E. coli by Introducing the Direct Sulfurylation Pathway of S. cerevisiae

Structures and Protein Engineering of the α‐Keto Acid C‐Methyltransferases SgvM and MrsA for Rational Substrate Transfer

Enzymatic S‐methylation of thiols catalyzed by different O‐methyltransferases

New inositol pyrophosphate prometabolites: specific organelle targeting, tissue penetration, and stable isotope labelling

Nuclear actin assembly is required for chromatin reorganization after mitosis as well as androgen receptor signaling

Structure, function and substrate preferences of archaeal S-adenosyl-l-homocysteine hydrolases

Structures and protein engineering of the [alpha]‐keto acid C‐methyltransferases SgvM and MrsA for rational substrate transfer

Enzymatic S ‐Methylation of Thiols Catalyzed by Different O ‐Methyltransferases

Expanding the Substrate Scope of N ‐ and O ‐Methyltransferases from Plants for Chemoselective Alkylation **

Enzymatic Synthesis of l ‐Methionine Analogues and Application in a Methyltransferase Catalysed Alkylation Cascade **

Biomimetic S ‐Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes **

Biomimetic S-adenosylmethionine regeneration starting from multiple byproducts enables biocatalytic alkylation with radical sam enzymes

Enzymatic synthesis of l‐methionine analogues and application in a methyltransferase catalysed alkylation cascade

Expanding the substrate scope of N‐ and O‐methyltransferases from plants for chemoselective alkylation

Funktionelle Charakterisierung der cobalaminabhängigen Radical SAM Methyltransferase QCMT aus Methanoculleus thermophilus

Modifying the makers: release factor hydroxylation, non-canonical nucleosides, and their influence on translation

Non‐canonical nucleosides: biomimetic triphosphorylation, incorporation into mRNA and effects on translation and structure

Targeting the deacylases SmSirt2 and hSirt2: inhibitors discovery and optimization

Using the CovPDB database as a basis for the HyperCys machine learning algorithm to simplify covalent drug design

Biosynthesis of Menaquinone in E. coli: Identification of an Elusive Isomer of SEPHCHC

Methyltransferases: Functions and Applications

A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique C α ‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase

A Cobalamin‐Dependent Radical SAM Enzyme Catalyzes the Unique C α ‐Methylation of Glutamine in Methyl‐Coenzyme M Reductase

Photoaffinity Capture Compounds to Profile the Magic Spot Nucleotide Interactomes **

Photoaffinity Capture Compounds to Profile the Magic Spot Nucleotide Interactomes **

A cobalamin‐dependent radical sam enzyme catalyzes the unique cα‐methylation of glutamine in methyl‐coenzyme m reductase

A cobalamin‐dependent radical SAM enzyme catalyzes the unique Cα‐methylation of glutamine in methyl‐coenzyme M reductase

Biosynthesis of menaquinone in E. coli: identification of an elusive isomer of SEPHCHC

Characterisation of family 2 polyphosphate kinases

Make or break: the thermodynamic equilibrium of polyphosphate kinase-catalysed reactions

Methyltransferases : : functions and applications

Photoaffinity capture compounds to profile the magic spot nucleotide interactomes**

Photoaffinity capture compounds to profile the magic spot nucleotide interactomes**

Multienzyme One‐Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids

Multienzyme One‐Pot Cascades Incorporating Methyltransferases for the Strategic Diversification of Tetrahydroisoquinoline Alkaloids

A bicyclic S-adenosylmethionine regenerationsystem applicable with different nucleosidesor nucleotides as cofactor building blocks

A multi-enzyme cascade reaction for the production of 2′3′-cGAMP

Biosynthesis and utilisation of PRPP and application to a cofactor regeneration system

Chorismate- and isochorismate converting enzymes: versatile catalysts acting on an important metabolic node

Multienzyme one‐pot cascades incorporating methyltransferases for the strategic diversification of tetrahydroisoquinoline alkaloids

Multienzyme one‐pot cascades incorporating methyltransferases for the strategic diversification of tetrahydroisoquinoline alkaloids

S-Adenosylhomocysteine hydrolase as a bottleneck in the biomimetic regeneration cycle of S-adenosylmethionine and its analogues

Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases

Channeling C1 metabolism toward S-adenosylmethionine-dependent conversion of estrogens to androgens in estrogen-degrading bacteria

Single-step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases

Several Polyphosphate Kinase 2 Enzymes Catalyse the Production of Adenosine 5′‐Polyphosphates

A Flexible Polyphosphate‐Driven Regeneration System for Coenzyme A Dependent Catalysis

Catalytic Alkylation Using a Cyclic S ‐Adenosylmethionine Regeneration System

Asymmetric C‐Alkylation by the S ‐Adenosylmethionine‐Dependent Methyltransferase SgvM