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Person

Ralf Erdmann

Chemiker

Name	Ralf Erdmann
Place	Deutschland
Gender	männlich
Academic degree	Prof. Dr. rer. nat.
Profession	Chemiker (characteristic profession)
Further information	Ruhr-Universität Bochum, Institut für Physiologische Chemie, Abt. für Systembiochemie
Record type	Person
GND-Identifier	143280147
Record ID	143280147
Involved in show all Recent advances in glycosome biogenesis and its implications for drug discovery Struktur- und Funktionsanalyse von Komponenten der peroxisomalen Proteinimport-Maschinerie in Saccharomyces cerevisiae Modulation of peroxisomal import by the PEX13 SH3 domain and a proximal FxxxF binding motif PEX1 is essential for glycosome biogenesis and trypanosomatid parasite survival Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate Quantitative analysis of peroxisome tracks using a Hidden Markov Model Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis Distinct conformational and energetic features define the specific recognition of (di) aromatic peptide motifs by PEX14 Dynamics of the translocation pore of the human peroxisomal protein import machinery Membrane binding and pore forming insertion of PEX5 into horizontal lipid bilayer Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes Determining the targeting specificity of the selective peroxisomal targeting factor Pex9 Highlight: structure and function of the peroxisomal translocon Development of novel PEX5-PEX14 protein-protein interaction (PPI) inhibitors based on an oxopiperazine template Isolation of glycosomes from Trypanosoma brucei Molecular basis of the glycosomal targeting of PEX11 and its mislocalization to mitochondrion in trypanosomes Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma Systematic multi‐level analysis of an organelle proteome reveals new peroxisomal functions Current advances in the function and biogenesis of peroxisomes and their roles in health and disease Challenges of Using Expansion Microscopy for Super‐resolved Imaging of Cellular Organelles Computer-Aided Design and Synthesis of a New Class of PEX14 Inhibitors: Substituted 2,3,4,5-Tetrahydrobenzo[F][1,4]oxazepines as Potential New Trypanocidal Agents Edgetic Perturbations Contribute to Phenotypic Variability in PEX26 Deficiency Novel trypanocidal inhibitors that block glycosome biogenesis by targeting PEX3–PEX19 interaction Challenges of Using Expansion Microscopy for Super‐resolved Imaging of Cellular Organelles Fluidity and lipid composition of membranes of peroxisomes, mitochondria and the ER from oleic acid-induced \(\textit {Saccharomyces cerevisiae}\) Membrane processing and steady-state regulation of the alternative peroxisomal import receptor Pex9p Pex14p phosphorylation modulates import of citrate synthase 2 into peroxisomes in saccharomyces cerevisiae Current Advances in Protein Import into Peroxisomes Structure-Activity Relationship in Pyrazolo[4,3- c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity Funktion und Regulation der Peroxine Pex14p und Pex17p in der peroxisomalen Biogenese der Hefe Saccharomyces cerevisiae Untersuchungen zum peroxisomalen Matrixprotein-import der Hefe Saccharomyces cerevisiae Nucleotide-dependent assembly of the peroxisomal receptor export complex Cysteine-specific ubiquitination protects the peroxisomal import receptor Pex5p against proteasomal degradation Molecular snapshots of the Pex1/6 AAA + complex in action Peroxisomal import reduces the proapoptotic activity of deubiquitinating enzyme USP2 Structural insights into cargo recognition by the yeast PTS1 receptor The Peroxisomal Targeting Signal 1 in sterol carrier protein 2 is autonomous and essential for receptor recognition Untersuchungen zur Biogenese von Peroxisomen : proteomische Charakterisierung der Interaktome von Pex14p und Pex3p in \(\textit {Saccharomyces cerevisiae}\) A proteomic approach towards the identification of the matrix protein content of the two types of microbodies in Neurospora crassa Beteiligung der PTS-Rezeptoren von Saccharomyces cerevisiae an der Translokation von Matrixproteinen über die peroxisomale Membran Proteomics characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling Saccharomyces cerevisiae Pex3p and Pex19p are required for proper localization and stability of peroxisomal membrane proteins Untersuchungen zur Biogenese von Peroxisomen in der Hefe Saccharomyces cerevisiae Isolierung und Charakterisierung peroxisomaler Mutanten von Saccharomyces cerevisiae und deren Verwendung zur Untersuchung der Biogenese von Peroxisomen Isolierung und Charakterisierung peroxisomaler Mutanten von Saccharomyces cerevisiae und deren Verwendung zur Untersuchung der Biogenese von Peroxisomen

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Katalog der Deutschen Nationalbibliothek

Ralf Erdmann

Recent advances in glycosome biogenesis and its implications for drug discovery

Struktur- und Funktionsanalyse von Komponenten der peroxisomalen Proteinimport-Maschinerie in Saccharomyces cerevisiae

Modulation of peroxisomal import by the PEX13 SH3 domain and a proximal FxxxF binding motif

PEX1 is essential for glycosome biogenesis and trypanosomatid parasite survival

Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate

Quantitative analysis of peroxisome tracks using a Hidden Markov Model

Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate

Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis

Distinct conformational and energetic features define the specific recognition of (di) aromatic peptide motifs by PEX14

Dynamics of the translocation pore of the human peroxisomal protein import machinery

Membrane binding and pore forming insertion of PEX5 into horizontal lipid bilayer

Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes

Determining the targeting specificity of the selective peroxisomal targeting factor Pex9

Highlight: structure and function of the peroxisomal translocon

Development of novel PEX5-PEX14 protein-protein interaction (PPI) inhibitors based on an oxopiperazine template

Isolation of glycosomes from Trypanosoma brucei

Molecular basis of the glycosomal targeting of PEX11 and its mislocalization to mitochondrion in trypanosomes

Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes

Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma

Systematic multi‐level analysis of an organelle proteome reveals new peroxisomal functions

Current advances in the function and biogenesis of peroxisomes and their roles in health and disease

Challenges of Using Expansion Microscopy for Super‐resolved Imaging of Cellular Organelles

Computer-Aided Design and Synthesis of a New Class of PEX14 Inhibitors: Substituted 2,3,4,5-Tetrahydrobenzo[F][1,4]oxazepines as Potential New Trypanocidal Agents

Edgetic Perturbations Contribute to Phenotypic Variability in PEX26 Deficiency

Novel trypanocidal inhibitors that block glycosome biogenesis by targeting PEX3–PEX19 interaction

Challenges of Using Expansion Microscopy for Super‐resolved Imaging of Cellular Organelles

Fluidity and lipid composition of membranes of peroxisomes, mitochondria and the ER from oleic acid-induced \(\textit {Saccharomyces cerevisiae}\)

Membrane processing and steady-state regulation of the alternative peroxisomal import receptor Pex9p

Pex14p phosphorylation modulates import of citrate synthase 2 into peroxisomes in saccharomyces cerevisiae

Current Advances in Protein Import into Peroxisomes

Structure-Activity Relationship in Pyrazolo[4,3- c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity

Funktion und Regulation der Peroxine Pex14p und Pex17p in der peroxisomalen Biogenese der Hefe Saccharomyces cerevisiae

Untersuchungen zum peroxisomalen Matrixprotein-import der Hefe Saccharomyces cerevisiae

Nucleotide-dependent assembly of the peroxisomal receptor export complex

Cysteine-specific ubiquitination protects the peroxisomal import receptor Pex5p against proteasomal degradation

Molecular snapshots of the Pex1/6 AAA + complex in action

Peroxisomal import reduces the proapoptotic activity of deubiquitinating enzyme USP2

Structural insights into cargo recognition by the yeast PTS1 receptor

The Peroxisomal Targeting Signal 1 in sterol carrier protein 2 is autonomous and essential for receptor recognition

Untersuchungen zur Biogenese von Peroxisomen : proteomische Charakterisierung der Interaktome von Pex14p und Pex3p in \(\textit {Saccharomyces cerevisiae}\)

A proteomic approach towards the identification of the matrix protein content of the two types of microbodies in Neurospora crassa

Beteiligung der PTS-Rezeptoren von Saccharomyces cerevisiae an der Translokation von Matrixproteinen über die peroxisomale Membran

Proteomics characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling

Saccharomyces cerevisiae Pex3p and Pex19p are required for proper localization and stability of peroxisomal membrane proteins

Untersuchungen zur Biogenese von Peroxisomen in der Hefe Saccharomyces cerevisiae

Isolierung und Charakterisierung peroxisomaler Mutanten von Saccharomyces cerevisiae und deren Verwendung zur Untersuchung der Biogenese von Peroxisomen

Isolierung und Charakterisierung peroxisomaler Mutanten von Saccharomyces cerevisiae und deren Verwendung zur Untersuchung der Biogenese von Peroxisomen